Day: 20 March 2024

Delirium

20 March 2024

Acute type a aortic dissection features and outcomes in octogenarians: a propensity score analysis

Interdiscip Cardiovasc Thorac Surg. 2024 Mar 20:ivae038. doi: 10.1093/icvts/ivae038. Online ahead of print.ABSTRACTOBJECTIVES: The clinical characteristics and early outcomes of surgical repair in octogenarians with...

Brain

20 March 2024

Pearls & Oy-sters: AARS2 Leukodystrophy-Tremor and Tribulations

Neurology. 2024 Apr 23;102(8):e209296. doi: 10.1212/WNL.0000000000209296. Epub 2024 Mar 20.ABSTRACTA 35-year-old woman with a progressive, bilateral upper limb tremor, personality change, behavioral disturbance, and primary...

Brain

20 March 2024

Gerstmann Syndrome Case-Control Study: Correlation between Brain Lesions & Functional Disability

Int Tinnitus J. 2024 Mar 18;27(2):247-252. doi: 10.5935/0946-5448.20230038. Online ahead of print.ABSTRACTDeep functional and structural neuroimaging of a series of Gerstmann's syndrome patients required high...

Brain

20 March 2024

Hemispheric engagement during the processing of affective adjectives-an ERP divided visual field study

Laterality. 2024 Mar 20:1-23. doi: 10.1080/1357650X.2024.2331278. Online ahead of print.ABSTRACTThe study looked into the hemispheres' involvement in emotional word encoding. It combined brain activity measures...

Brain

20 March 2024

Prenatal Fluoxetine Exposure Influences Glucocorticoid Receptor-Mediated Activity in the Prefrontal Cortex of Adolescent Rats Exposed to Acute Stress

ACS Chem Neurosci. 2024 Mar 20. doi: 10.1021/acschemneuro.3c00856. Online ahead of print.ABSTRACTAny deviation from the programmed processes of brain development may modify its formation and...

Brain

20 March 2024

Overview of the Evolution of Hypertension: From Ancient Chinese Emperors to Today

Hypertension. 2024 Apr;81(4):717-726. doi: 10.1161/HYPERTENSIONAHA.124.21953. Epub 2024 Feb 22.ABSTRACTHypertension is one of the most commonly treated conditions in modern medical practice, but despite its long...

Education

20 March 2024

Academic and professional profile of cardiology fellowship graduates of National Institute of Cardiology Ignacio Chávez from 2000 to 2015

Arch Cardiol Mex. 2024;94(1):55-64. doi: 10.24875/ACM.22000279.ABSTRACTBACKGROUND: The Ignacio Chávez National Institute of Cardiology (NIC) has positioned itself as an international benchmark in cardiovascular medical education,...

Education

20 March 2024

Impact of ABCB1 genetic polymorphism on carbamazepine dose requirement among Southern Indian persons with epilepsy

Drug Metab Pers Ther. 2024 Mar 20. doi: 10.1515/dmpt-2023-0054. Online ahead of print.ABSTRACTOBJECTIVES: Carbamazepine (CBZ) is one of the oldest, yet first line drugs for...

Education

20 March 2024

The Arrivals Gate at Heathrow Airport

Clin Infect Dis. 2024 Mar 20:ciae089. doi: 10.1093/cid/ciae089. Online ahead of print.NO ABSTRACTPMID:38507242 | DOI:10.1093/cid/ciae089

Education

20 March 2024

Standardizing Chondrocyte Isolation and Articular Cartilage Decellularization: A Versatile Bioink for Tissue Engineering Applications

Methods Mol Biol. 2024 Mar 21. doi: 10.1007/7651_2024_534. Online ahead of print.ABSTRACTThe extracellular matrix (ECM) is a noncellular component of tissues that provides structural and...

Education

20 March 2024

Association between amiodarone use and risk of cataract: a population-based active-comparator study

Postgrad Med J. 2024 Mar 20:qgae034. doi: 10.1093/postmj/qgae034. Online ahead of print.ABSTRACTBACKGROUND: Despite previous concerns about ocular side effects related to amiodarone, the relationship between...

Education

20 March 2024

Bone mineral density, turnover, and microarchitecture assessed by second-generation high-resolution peripheral quantitative computed tomography in patients with Sheehan’s syndrome

Osteoporos Int. 2024 Mar 20. doi: 10.1007/s00198-024-07062-z. Online ahead of print.ABSTRACTSheehan's syndrome (SS) is a rare but well-characterized cause of hypopituitarism. Data on skeletal health...

Education

20 March 2024

ChatGPT’s limited accuracy in generating anatomical images for medical education

Skeletal Radiol. 2024 Mar 20. doi: 10.1007/s00256-024-04655-x. Online ahead of print.NO ABSTRACTPMID:38506966 | DOI:10.1007/s00256-024-04655-x

Dementia

20 March 2024

Alzheimer’s Disease – Managing Stages of Dementia

N Engl J Med. 2024 Mar 21;390(12):e29. doi: 10.1056/NEJMp2310177.NO ABSTRACTPMID:38507749 | DOI:10.1056/NEJMp2310177

Dementia

20 March 2024

Burden of Neurologic Health Care and Incident Neurologic Diagnoses in the Year After COVID-19 or Influenza Hospitalization

Neurology. 2024 Apr 23;102(8):e209248. doi: 10.1212/WNL.0000000000209248. Epub 2024 Mar 20.ABSTRACTBACKGROUND AND OBJECTIVE: Following the outbreak of viral infections from the severe acute respiratory syndrome coronavirus...

Dementia

20 March 2024

Listening Effort, An Overview of App Validation and Testing by the Audiology 4 all Project

Int Tinnitus J. 2024 Mar 18;27(2):97-103. doi: 10.5935/0946-5448.20230016. Online ahead of print.ABSTRACTOBJECTIVE: To describe an application's development and validation process that aims to track hearing...

Dementia

20 March 2024

Reactive astrocytes secrete the chaperone HSPB1 to mediate neuroprotection

Sci Adv. 2024 Mar 22;10(12):eadk9884. doi: 10.1126/sciadv.adk9884. Epub 2024 Mar 20.ABSTRACTMolecular chaperones are protective in neurodegenerative diseases by preventing protein misfolding and aggregation, such as...

Dementia

20 March 2024

Predicting Progression From Mild Cognitive Impairment to Alzheimer’s Dementia With Adversarial Attacks

IEEE J Biomed Health Inform. 2024 Mar 20;PP. doi: 10.1109/JBHI.2024.3373703. Online ahead of print.ABSTRACTEarly diagnosisof Alzheimer's disease plays a crucial role in treatment planning that...

Dementia

20 March 2024

Emotion Regulation, Coping Strategies, and Hazardous Drinking Among Family Caregivers of People With Alzheimer’s Disease and Related Dementias

Res Gerontol Nurs. 2024 Mar-Apr;17(2):81-90. doi: 10.3928/19404921-20240229-02. Epub 2024 Mar 1.ABSTRACTPURPOSE: The current study investigated hazardous drinking and alcohol use disorders among 453 family caregivers...

Dementia

20 March 2024

Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells

Geroscience. 2024 Mar 20. doi: 10.1007/s11357-024-01117-z. Online ahead of print.ABSTRACTChronic periodontitis and its keystone pathogen, Porphyromonas gingivalis, have increasingly been linked with Alzheimer's disease (AD)....

Suicide

20 March 2024

Perinatal Mood And Anxiety Disorders Rose Among Privately Insured People, 2008-20

Health Aff (Millwood). 2024 Mar 20:101377hlthaff202301437. doi: 10.1377/hlthaff.2023.01437. Online ahead of print.ABSTRACTNationwide, perinatal mood and anxiety disorder (PMAD) diagnoses among privately insured people increased by...

PTSD

20 March 2024

Diagnostic Accuracy of the Primary Care PTSD for DSM-5 Screen (PC-PTSD-5) in Demographic and Diagnostic Subgroups of Veterans

J Gen Intern Med. 2024 Mar 20. doi: 10.1007/s11606-024-08719-5. Online ahead of print.ABSTRACTBACKGROUND: The Primary Care PTSD Screen for DSM-5 (PC-PTSD-5) is a screening instrument...

Psychosis

20 March 2024

Labyrinthine and Neuroscientific Impact of Schizophrenia in the Criminal Justice System

Int Tinnitus J. 2024 Mar 18;27(2):231-237. doi: 10.5935/0946-5448.20230035. Online ahead of print.ABSTRACTSchizophrenia, a complex neuropsychiatric condition, manifests with severe neurobiological and psychosocial symptoms, including psychosis,...

Artificial Intelligence

20 March 2024

Single-sequence protein structure prediction by integrating protein language models

Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2308788121. doi: 10.1073/pnas.2308788121. Epub 2024 Mar 20.ABSTRACTProtein structure prediction has been greatly improved by deep learning...

Artificial Intelligence

20 March 2024

Functional Neural Networks for High-Dimensional Genetic Data Analysis

IEEE/ACM Trans Comput Biol Bioinform. 2024 Mar 20;PP. doi: 10.1109/TCBB.2024.3364614. Online ahead of print.ABSTRACTArtificial intelligence (AI) is a thriving research field with many successful applications...

Artificial Intelligence

20 March 2024

A Secure and Interpretable AI for Smart Healthcare System: A Case Study on Epilepsy Diagnosis Using EEG Signals

IEEE J Biomed Health Inform. 2024 Mar 20;PP. doi: 10.1109/JBHI.2024.3366341. Online ahead of print.ABSTRACTThe efficient patient-independent and interpretable framework for electroencephalogram (EEG) epileptic seizure detection...

Artificial Intelligence

20 March 2024

Evaluation of vital signs through a mobile application in patients with heart failure: a opportunity for remote titration?

Arch Cardiol Mex. 2024;94(1):86-94. doi: 10.24875/ACM.22000221.ABSTRACTBACKGROUND: Virtual consultations have increased exponentially, but a limitation is the inability to assess vital signs (VS). This is particularly...

Artificial Intelligence

20 March 2024

Contribution of Artificial Intelligence to the Identification of Protein-Protein Interactions: A Case Study on PAR-3 and Its Partner Adapter Molecule Crk

Methods Mol Biol. 2024 Mar 21. doi: 10.1007/7651_2024_530. Online ahead of print.ABSTRACTProtein-protein interactions (PPIs) are known to be involved in most cellular functions, and a...

Artificial Intelligence

20 March 2024

Autoimmune encephalitis: what the radiologist needs to know

Neuroradiology. 2024 Mar 20. doi: 10.1007/s00234-024-03318-x. Online ahead of print.ABSTRACTAutoimmune encephalitis is a relatively novel nosological entity characterized by an immune-mediated damage of the central...

Artificial Intelligence

20 March 2024

Leveraging the Capabilities of AI: Novice Neurology-Trained Operators Performing Cardiac POCUS in Patients with Acute Brain Injury

Neurocrit Care. 2024 Mar 20. doi: 10.1007/s12028-024-01953-z. Online ahead of print.ABSTRACTBACKGROUND: Cardiac point-of-care ultrasound (cPOCUS) can aid in the diagnosis and treatment of cardiac disorders....

Impulse Control Disorder

20 March 202412 May 2024

A comprehensive update on the ADMET considerations for a2o calcium channel ligand medications for treating restless legs syndrome

Expert Opin Drug Metab Toxicol. 2024 Mar 15:1-10. doi: 10.1080/17425255.2024.2329738. Online ahead of print.ABSTRACTINTRODUCTION: Restless legs syndrome/Willis-Ekbom disease (RLS/WED) is a sleep-related sensory-motor disorder associated...

Impulse Control Disorder

20 March 202421 March 2024

Stimulant prodrugs: A pharmacological and clinical assessment of their role in treating ADHD and binge-eating disorder

Adv Pharmacol. 2024;99:251-286. doi: 10.1016/bs.apha.2023.10.002. Epub 2023 Oct 25.ABSTRACTIn this review, we critically evaluate the contribution of prodrugs to treating two related psychiatric disorders, attention-deficit...

Impulse Control Disorder

20 March 202421 March 2024

Subjective feelings associated with expectations and rewards during risky decision-making in impulse control disorder

Sci Rep. 2024 Mar 4;14(1):4627. doi: 10.1038/s41598-024-53076-2.ABSTRACTImpulse Control Disorder (ICD) in Parkinson's disease is a behavioral addiction induced by dopaminergic therapies, but otherwise unclear etiology....

Conduct Disorder

20 March 2024

Commentary: Early intervention for conduct problems as a child protection strategy – reflections on Nobakht et al. (2023)

J Child Psychol Psychiatry. 2024 Feb 29. doi: 10.1111/jcpp.13967. Online ahead of print.ABSTRACTAdverse childhood experiences (ACEs), including child maltreatment and interparental aggression, are known to...

Conduct Disorder

20 March 2024

Study Preregistration: Understanding the Etiology of Externalizing Problems in Young Children: The Roles of Callous-Unemotional Traits and Irritability

J Am Acad Child Adolesc Psychiatry. 2024 Mar;63(3):376-378. doi: 10.1016/j.jaac.2023.09.549. Epub 2023 Dec 7.ABSTRACTExternalizing behavioral problems in young children are associated with later delinquency and...

Oxford Talks

20 March 2024

Biophysics HT Seminar 4

tbc

Self Harm

20 March 2024

Interventions for Self-Harm and Suicidal Ideation in Africa: A Systematic Review

Arch Suicide Res. 2024 Mar 20:1-25. doi: 10.1080/13811118.2024.2316168. Online ahead of print.ABSTRACTBACKGROUND: Self-harm and suicidal ideation are increasing public health concerns globally and are paramount...

Neuropathology

20 March 2024

Decoding Suicide Decedent Profiles and Signs of Suicidal Intent Using Latent Class Analysis

JAMA Psychiatry. 2024 Mar 20. doi: 10.1001/jamapsychiatry.2024.0171. Online ahead of print.ABSTRACTIMPORTANCE: Suicide rates in the US increased by 35.6% from 2001 to 2021. Given that...

Mental Health

20 March 2024

Using a Rapid Learning Health System for Stratified Care in Emerging Adult Mental Health Services: Protocol for the Implementation of Patient-Reported Outcome Measures

JMIR Res Protoc. 2024 Mar 20;13:e51667. doi: 10.2196/51667.ABSTRACTBACKGROUND: Mental illness among emerging adults is often difficult to ameliorate due to fluctuating symptoms and heterogeneity. Recently,...

Forensic Psychiatry

20 March 2024

Age of Alzheimer’s disease diagnosis in people with Down syndrome and associated factors: Results from the Horizon 21 European Down syndrome consortium

Alzheimers Dement. 2024 Mar 20. doi: 10.1002/alz.13779. Online ahead of print.ABSTRACTINTRODUCTION: People with Down syndrome (DS) have high risk of developing Alzheimer's disease (AD). This...

Anxiety

20 March 2024

‘My child could have died’: counterfactual thoughts and psychological distress in parents of trauma survivors

Eur J Psychotraumatol. 2024;15(1):2326736. doi: 10.1080/20008066.2024.2326736. Epub 2024 Mar 20.ABSTRACTBackground: After exposure to a potentially traumatic event, survivors may experience thoughts about 'what could have...

Addiction

20 March 2024

Efficacy of Integrating the Management of Pain and Addiction via Collaborative Treatment (IMPACT) in Individuals With Chronic Pain and Opioid Use Disorder: Protocol for a Randomized Clinical Trial of a Digital Cognitive Behavioral Treatment

JMIR Res Protoc. 2024 Mar 20;13:e54342. doi: 10.2196/54342.ABSTRACTBACKGROUND: Chronic pain is common among individuals with opioid use disorder (OUD) who are maintained on medications for...

Addiction

20 March 2024

Children as next of kin’s experiences, practices, and voice in everyday life: a systematic review of studies with Norwegian data (2010-2022)

Scand J Public Health. 2024 Mar 20:14034948241232040. doi: 10.1177/14034948241232040. Online ahead of print.ABSTRACTAims: This systematic review aims to identify and describe how children of parents...

Medicine

20 March 2024

Parents’ User Experience Accessing and Using a Web-Based Map of COVID-19 Recommendations for Health Decision-Making: Qualitative Descriptive Study

JMIR Form Res. 2024 Mar 20;8:e53593. doi: 10.2196/53593.ABSTRACTBACKGROUND: The eCOVID19 Recommendations Map & Gateway to Contextualization (RecMap) website was developed to identify all COVID-19 guidelines,...

Medicine

20 March 2024

The Impact of Parental Electronic Health Literacy on Disease Management and Outcomes in Pediatric Type 1 Diabetes Mellitus: Cross-Sectional Clinical Study

JMIR Pediatr Parent. 2024 Mar 20;7:e54807. doi: 10.2196/54807.ABSTRACTBACKGROUND: Despite the growing uptake of smart technologies in pediatric type 1 diabetes mellitus (T1DM) care, little is...

Medicine

20 March 2024

Food allergy and environmental contamination

Rev Alerg Mex. 2023 Dec 31;70(4):313-318. doi: 10.29262/ram.v70i4.1342.ABSTRACTThe interaction between genetic potential and the environment, especially increased urbanization and inadequate waste management, contributes to the...

Medicine

20 March 2024

Food desensitization

Rev Alerg Mex. 2023 Dec 31;70(4):284-292. doi: 10.29262/ram.v70i4.1339.ABSTRACTIn recent times, the primary approach to treating food allergies involved strict avoidance of the triggering allergen. Many...

Medicine

20 March 2024

Phenotypes and endotypes of food allergy

Rev Alerg Mex. 2023 Dec 31;70(4):230-233. doi: 10.29262/ram.v70i4.1331.ABSTRACTFood allergy is a common event, especially in the pediatric population, affecting between 3-6% of children. There are...

Medicine

20 March 2024

Epidemiology of food allergy

Rev Alerg Mex. 2023 Dec 31;70(4):211-213. doi: 10.29262/ram.v70i4.1328.ABSTRACTFood allergy is very common throughout the world and has become a major public health problem, with 220...

Medicine

20 March 2024

Introduction to food allergy

Rev Alerg Mex. 2023 Dec 31;70(4):208-210. doi: 10.29262/ram.v70i4.1308.ABSTRACTFood allergy is a common chronic disorder that affects infants, children, adolescents, and adults. The prevalence of food...

Medicine

20 March 2024

The Effect of Childhood Obesity on Intraocular Pressure, Corneal Biomechanics, Retinal Nerve Fiber Layer and Central Macular Thickness

J Glaucoma. 2024 Mar 19. doi: 10.1097/IJG.0000000000002372. Online ahead of print.ABSTRACTPRCIS: Elevated corneal hysteresis (CH) and resistance factor (CRF) in obese and over-weight children imply...

Medicine

20 March 2024

Peripheral arterial catheter securement and catheter survival in the pediatric intensive care unit

J Vasc Access. 2024 Mar 20:11297298241236405. doi: 10.1177/11297298241236405. Online ahead of print.ABSTRACTBACKGROUND: Peripheral arterial catheters (PACs), and their associated complications, are common in the pediatric...

Medicine

20 March 2024

Lime-Induced Phytophotodermatitis: A Rash That Requires Explicit Questioning

J Allergy Clin Immunol Pract. 2024 Mar 20:S2213-2198(24)00212-5. doi: 10.1016/j.jaip.2024.02.035. Online ahead of print.NO ABSTRACTPMID:38506786 | DOI:10.1016/j.jaip.2024.02.035

Anorexia Nervosa

20 March 2024

Covid-19 And Surgical Pathologies In General Surgery Of CHU Gabriel Toure Of Bamako

Mali Med. 2022;38(1):7-11.ABSTRACTINTRODUCTION: The pure digestive form of COVID-19 is possible and initially considered rare. Our objectives were to determine the frequency of COVID-19 in...

Alcoholism

20 March 2024

Iron metabolism and ferroptosis in Non-alcoholic fatty liver disease: what is our next step?

Am J Physiol Endocrinol Metab. 2024 Mar 20. doi: 10.1152/ajpendo.00260.2023. Online ahead of print.ABSTRACTNon-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease...

Alcoholism

20 March 2024

Sex differences in mortality and liver-related events in non-alcoholic fatty liver disease: A systematic review and meta-analysis

Liver Int. 2024 Mar 20. doi: 10.1111/liv.15910. Online ahead of print.ABSTRACTBACKGROUND & AIMS: Many systematic reviews explore the association of non-alcoholic fatty liver disease (NAFLD)...

Alcoholism

20 March 2024

Alcohol, health loss and mortality: can wine really save the good name of moderate alcohol consumption?

Pol Arch Intern Med. 2024 Mar 20:16708. doi: 10.20452/pamw.16708. Online ahead of print.ABSTRACTIt is estimated that one third of the world's population consumes alcohol. At...

Alcoholism

20 March 2024

Evaluation of cardiovascular risk factors among workers in a food industry in Mali

Mali Med. 2022;38(1):1-6.ABSTRACTOBJECTIVE: It consisted in evaluating the cardiovascular risk factors and the overall cardiovascular risk among the personnel of the company of the breweries...

Alcoholism

20 March 2024

Time trends in liver-related mortality in people with and without diabetes: Results from a population based study

J Clin Endocrinol Metab. 2024 Mar 20:dgae182. doi: 10.1210/clinem/dgae182. Online ahead of print.ABSTRACTCONTEXT: Patients with diabetes are at increased risk of dying from liver-related events,...

Autism

20 March 2024

Indonesian nurses’ awareness and application of reasonable adjustments when caring for people with intellectual disability and/or autism

Int Nurs Rev. 2024 Mar 20. doi: 10.1111/inr.12959. Online ahead of print.ABSTRACTAIM: This study aimed to understand Indonesian nurses' familiarity with the concept of reasonable...

Education

20 March 2024

Evaluating Effectiveness of an Online LGBTQIA+ Health Course for Medical Students

Fam Med. 2024 Mar 18. doi: 10.22454/FamMed.2024.956897. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: Despite the increasing number of sexual and gender minority (SGM) patients in...

Education

20 March 2024

Setting the Target: Comparing Family Medicine Among US Allopathic Target Schools

Fam Med. 2024 Mar 11. doi: 10.22454/FamMed.2024.510377. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: Despite the persistent primary care physician shortage over 2 decades of allopathic...

Education

20 March 2024

Novel PANK2 Variant in Asian Indians with Atypical Pantothenate Kinase Associated Neurodegeneration

Mov Disord. 2024 Mar 20. doi: 10.1002/mds.29737. Online ahead of print.NO ABSTRACTPMID:38506547 | DOI:10.1002/mds.29737

Education

20 March 2024

Guidelines of the Polish Society of Gynecologists and Obstetricians on the diagnosis and management of pregnancies complicated by prelabor rupture of the membranes

Ginekol Pol. 2024 Mar 20. doi: 10.5603/gpl.98339. Online ahead of print.NO ABSTRACTPMID:38506477 | DOI:10.5603/gpl.98339

Education

20 March 2024

Medical Students’ Speak Up Barriers: A Randomized Controlled Trial With Written Vignettes

J Patient Saf. 2024 Mar 18. doi: 10.1097/PTS.0000000000001227. Online ahead of print.ABSTRACTOBJECTIVES: Little is known about medical students' speak-up barriers upon recognizing or becoming aware...

ADHD

20 March 2024

Attention-Deficit/Hyperactivity Disorder Medications and Work Disability and Mental Health Outcomes

JAMA Netw Open. 2024 Mar 4;7(3):e242859. doi: 10.1001/jamanetworkopen.2024.2859.ABSTRACTIMPORTANCE: Individuals with attention-deficit/hyperactivity disorder (ADHD) often have comorbid psychiatric conditions. Relatively little is known about how specific...

ADHD

20 March 2024

A state-of-the-art overview of candidate diagnostic biomarkers for attention-Deficit/Hyperactivity disorder (ADHD)

Expert Rev Mol Diagn. 2024 Mar 20. doi: 10.1080/14737159.2024.2333277. Online ahead of print.ABSTRACTINTRODUCTION: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neurodevelopmental conditions and...

Dementia

20 March 202412 May 2024

Skin Biopsy Detection of Phosphorylated a-Synuclein in Patients With Synucleinopathies

JAMA. 2024 Mar 20. doi: 10.1001/jama.2024.0792. Online ahead of print.ABSTRACTIMPORTANCE: Finding a reliable diagnostic biomarker for the disorders collectively known as synucleinopathies (Parkinson disease [PD],...

Dementia

20 March 2024

Strategies used during the cognitive evaluation of older adults with dual sensory impairment: a scoping review

Age Ageing. 2024 Mar 1;53(3):afae051. doi: 10.1093/ageing/afae051.ABSTRACTBACKGROUND: Dual sensory impairment (DSI), the combination of visual and hearing impairments, is associated with increased risk for age-related...

Dementia

20 March 2024

Dementias Platform UK: Bringing genetics into life

Alzheimers Dement. 2024 Mar 20. doi: 10.1002/alz.13782. Online ahead of print.ABSTRACTINTRODUCTION: The Dementias Platform UK (DPUK) Data Portal is a data repository bringing together a...

Dementia

20 March 2024

Navigating ethnic diversity: Rethinking dementia prevention in Aotearoa New Zealand

Aust N Z J Psychiatry. 2024 Mar 20:48674241240586. doi: 10.1177/00048674241240586. Online ahead of print.NO ABSTRACTPMID:38506472 | DOI:10.1177/00048674241240586

Dementia

20 March 2024

Racial, ethnic, and rural disparities in distance to physicians among decedents with Alzheimer’s disease and related dementias in Washington State

Alzheimers Dement. 2024 Mar 20. doi: 10.1002/alz.13756. Online ahead of print.ABSTRACTINTRODUCTION: Distance to physicians may explain some of the disparities in Alzheimer's disease and related...

Suicide

20 March 2024

Examining Passively Collected Smartphone-Based Data in the Days Prior to Psychiatric Hospitalization for a Suicidal Crisis: Comparative Case Analysis

JMIR Form Res. 2024 Mar 20;8:e55999. doi: 10.2196/55999.ABSTRACTBACKGROUND: Digital phenotyping has seen a broad increase in application across clinical research; however, little research has implemented...

PTSD

20 March 2024

Gender, sex and complex PTSD clinical presentation: a systematic review

Eur J Psychotraumatol. 2024;15(1):2320994. doi: 10.1080/20008066.2024.2320994. Epub 2024 Mar 20.ABSTRACTBackground: Post-traumatic stress disorder (PTSD) prevalence and clinical presentation reportedly vary with gender and/or sex. Equivalent...

PTSD

20 March 2024

Dynamic symptom associations in posttraumatic stress disorder: a network approach

Eur J Psychotraumatol. 2024;15(1):2317675. doi: 10.1080/20008066.2024.2317675. Epub 2024 Mar 20.ABSTRACTBackground and objective: The current study aimed to investigate the within-day symptom dynamics in PTSD patients,...

Psychosis

20 March 2024

Baseline Antipsychotic Dose and Transition to Psychosis in Individuals at Clinical High Risk: A Systematic Review and Meta-Analysis

JAMA Psychiatry. 2024 Mar 20. doi: 10.1001/jamapsychiatry.2024.0178. Online ahead of print.ABSTRACTIMPORTANCE: Emerging meta-analytical evidence indicates that baseline exposure to antipsychotics is associated with an increased...

Artificial Intelligence

20 March 2024

Incorporating ChatGPT in Medical Informatics Education: Mixed Methods Study on Student Perceptions and Experiential Integration Proposals

JMIR Med Educ. 2024 Mar 20;10:e51151. doi: 10.2196/51151.ABSTRACTBACKGROUND: The integration of artificial intelligence (AI) technologies, such as ChatGPT, in the educational landscape has the potential...

Artificial Intelligence

20 March 2024

Preliminary Evidence of the Use of Generative AI in Health Care Clinical Services: Systematic Narrative Review

JMIR Med Inform. 2024 Mar 20;12:e52073. doi: 10.2196/52073.ABSTRACTBACKGROUND: Generative artificial intelligence tools and applications (GenAI) are being increasingly used in health care. Physicians, specialists, and...

Artificial Intelligence

20 March 2024

Effectiveness of a Web-based and Mobile Therapy Chatbot on Anxiety and Depressive Symptoms in Subclinical Young Adults: Randomized Controlled Trial

JMIR Form Res. 2024 Mar 20;8:e47960. doi: 10.2196/47960.ABSTRACTBACKGROUND: There has been an increased need to provide specialized help for people with depressive and anxiety symptoms,...

Artificial Intelligence

20 March 2024

Artificial Intelligence-Generated Draft Replies to Patient Inbox Messages

JAMA Netw Open. 2024 Mar 4;7(3):e243201. doi: 10.1001/jamanetworkopen.2024.3201.ABSTRACTIMPORTANCE: The emergence and promise of generative artificial intelligence (AI) represent a turning point for health care. Rigorous...

Artificial Intelligence

20 March 2024

Novel Technologies in Artificial Intelligence and Telemedicine for Glaucoma Screening

J Glaucoma. 2024 Mar 20. doi: 10.1097/IJG.0000000000002367. Online ahead of print.ABSTRACTPURPOSE: To provide an overview of novel technologies in telemedicine and artificial intelligence (AI) approaches...

Artificial Intelligence

20 March 2024

Insufficient Sleep is Associated With Increasing Trends in Adolescent Suicidal Behaviors

J Adolesc Health. 2024 Mar 20:S1054-139X(24)00066-1. doi: 10.1016/j.jadohealth.2024.01.030. Online ahead of print.ABSTRACTPURPOSE: Youth suicide has been increasing and became a public health concern worldwide. Identifying...

Artificial Intelligence

20 March 2024

Does crown, root, and bone visualization in a clear aligner virtual setup impact treatment decisions?

Am J Orthod Dentofacial Orthop. 2024 Mar 19:S0889-5406(24)00061-1. doi: 10.1016/j.ajodo.2024.01.014. Online ahead of print.ABSTRACTINTRODUCTION: Clear aligner technology based on a machine learning algorithm is currently...

Artificial Intelligence

20 March 2024

Deep Learning-based Approach for Brainstem and Ventricular MR Planimetry: Application in Patients with Progressive Supranuclear Palsy

Radiol Artif Intell. 2024 Mar 20:e230151. doi: 10.1148/ryai.230151. Online ahead of print.ABSTRACT"Just Accepted" papers have undergone full peer review and have been accepted for publication...

Artificial Intelligence

20 March 2024

Impact of Deep Learning Image Reconstruction Methods on MRI Throughput

Radiol Artif Intell. 2024 Mar 20:e230181. doi: 10.1148/ryai.230181. Online ahead of print.ABSTRACT"Just Accepted" papers have undergone full peer review and have been accepted for publication...

Artificial Intelligence

20 March 2024

Carbon Nanofibrous Aerogels Derived from Electrospun Polyimide for Multifunctional Piezoresistive Sensors

ACS Appl Mater Interfaces. 2024 Mar 20. doi: 10.1021/acsami.4c00452. Online ahead of print.ABSTRACTThe fabrication of carbon aerogels with ultralow density, high electrical conductivity, and ultraelasticity...

Self Harm

20 March 2024

Penetrating injury to the left ventricle caused by attempted suicide-a case report

J Surg Case Rep. 2024 Mar 17;2024(3):rjae159. doi: 10.1093/jscr/rjae159. eCollection 2024 Mar.ABSTRACTPenetrating cardiac injuries are rare but are one of the most urgent emergencies because...

Neuropathology

20 March 2024

Clinical and genomic characterization of chemoradiation-resistant HPV-positive oropharyngeal squamous cell carcinoma

Front Oncol. 2024 Mar 5;14:1336577. doi: 10.3389/fonc.2024.1336577. eCollection 2024.ABSTRACTINTRODUCTION: Most patients with HPV-positive oropharyngeal squamous cell carcinoma (OPSCC) have an excellent response to chemoradiation, and...

Forensic Psychiatry

20 March 2024

Exploring the Association Between Textual Parameters and Psychological and Cognitive Factors

Psychol Res Behav Manag. 2024 Mar 13;17:1139-1150. doi: 10.2147/PRBM.S460503. eCollection 2024.ABSTRACTBACKGROUND: Textual data analysis has become a popular method for examining complex human behavior in...

Forensic Psychiatry

20 March 2024

Neurobiological evidence and criminal competencies

Behav Sci Law. 2024 Mar 19. doi: 10.1002/bsl.2655. Online ahead of print.ABSTRACTNeuroimaging and other neurobiological evidences are increasingly introduced in criminal litigation, especially when a...

Forensic Psychiatry

20 March 2024

Cannabis exposure during pregnancy and perinatal outcomes: A cohort study

Acta Obstet Gynecol Scand. 2024 Mar 19. doi: 10.1111/aogs.14818. Online ahead of print.ABSTRACTINTRODUCTION: Cannabis potency and its use during pregnancy have increased in the last...

Bipolar Disorder

20 March 2024

The emerging neuroimmune hypothesis of bipolar disorder: An updated overview of neuroimmune and microglial findings

J Neurochem. 2024 Mar 19. doi: 10.1111/jnc.16098. Online ahead of print.ABSTRACTBipolar disorder (BD) is a severe and multifactorial disease, with onset usually in young adulthood,...

Bipolar Disorder

20 March 2024

Spanish validation of the short version of the racing and crowded thoughts questionnaire (RCTQ-13)

BMC Psychiatry. 2024 Mar 19;24(1):214. doi: 10.1186/s12888-024-05618-1.ABSTRACTBACKGROUND: The Racing and Crowded Thoughts Questionnaire (RCTQ-13) is the most widely used specific scale for the measurement of...

Bipolar Disorder

20 March 2024

Perceived loneliness and social support in bipolar disorder: relation to suicidal ideation and attempts

Int J Bipolar Disord. 2024 Mar 20;12(1):8. doi: 10.1186/s40345-024-00329-8.ABSTRACTBACKGROUND: The suicide rate in bipolar disorder (BD) is among the highest across all psychiatric disorders. Identifying...

Anxiety

20 March 2024

Do dental anxiety and satisfaction with dental professionals modify the association between affordability and dental service use? A population-based longitudinal study of Australian adults

J Public Health Dent. 2024 Mar 20. doi: 10.1111/jphd.12608. Online ahead of print.ABSTRACTOBJECTIVES: This study aimed to assess the association between affordability in terms of...

Anxiety

20 March 2024

Post-acute COVID-19 syndrome in previously hospitalized patients

J Nurs Scholarsh. 2024 Mar 20. doi: 10.1111/jnu.12967. Online ahead of print.ABSTRACTINTRODUCTION: With the prolongation of the COVID-19 pandemic, more individuals are experiencing sequelae after...

Anxiety

20 March 2024

Effectiveness and family experiences of interventions promoting partnerships between families and pediatric and neonatal intensive care units: a mixed methods systematic review

JBI Evid Synth. 2024 Mar 20. doi: 10.11124/JBIES-23-00034. Online ahead of print.ABSTRACTOBJECTIVE: The objective of this mixed methods review was to examine the effectiveness and...

Addiction

20 March 2024

ApoE4 dysregulation incites depressive symptoms and mitochondrial impairments in mice

J Cell Mol Med. 2024 Apr;28(7):e18160. doi: 10.1111/jcmm.18160.ABSTRACTApolipoprotein E4 (ApoE4) is involved in the stress-response processes and is hypothesized to be a risk factor for...

Addiction

20 March 2024

Alcohol Treatment Access and Engagement Among Women in the USA: a Targeted Review of the Literature 2012-2022

Curr Addict Rep. 2023 Dec;10:638-648. doi: 10.1007/s40429-023-00515-1. Epub 2023 Sep 12.ABSTRACTPURPOSE OF REVIEW: The purpose of this review is to examine recent literature (2012-2022) on...

Addiction

20 March 2024

Antineuropathic Pain Management After Orthopedic Surgery: A Systematic Review

Orthop Rev (Pavia). 2024 Mar 17;16:93012. doi: 10.52965/001c.93012. eCollection 2024.ABSTRACTBACKGROUND: The opioid crisis has become a present concern in the medical field. In an effort...

Addiction

20 March 2024

Alcohol and cannabis co-use: Receptiveness to treatments and application to intervention planning

J Stud Aff Res Pract. 2024;61(1):86-102. doi: 10.1080/19496591.2023.2177104. Epub 2023 May 16.ABSTRACTGiven the prevalence of alcohol and cannabis co-use among college students, prevention for co-use...

Addiction

20 March 2024

Digital Being: social media and the predictive mind

Neurosci Conscious. 2024 Mar 18;2024(1):niae008. doi: 10.1093/nc/niae008. eCollection 2024.ABSTRACTSocial media is implicated today in an array of mental health concerns. While concerns around social media...

GWAS

20 March 2024

Utilizing systematic Mendelian randomization to identify potential therapeutic targets for mania

Front Psychiatry. 2024 Mar 5;15:1375209. doi: 10.3389/fpsyt.2024.1375209. eCollection 2024.ABSTRACTBACKGROUND: Mania has caused incalculable economic losses for patients, their families, and even society, but there is...

Psychiatry

20 March 2024

A fully spiking coupled model of a deep neural network and a recurrent attractor explains dynamics of decision making in an object recognition task

J Neural Eng. 2024 Mar 20;21(2). doi: 10.1088/1741-2552/ad2d30.ABSTRACTObjective.Object recognition and making a choice regarding the recognized object is pivotal for most animals. This process in...

Medicine

20 March 2024

Availability and utilization of endoscopic retrograde cholangiopancreatography at children’s hospitals

J Pediatr Gastroenterol Nutr. 2024 Mar 20. doi: 10.1002/jpn3.12183. Online ahead of print.ABSTRACTOBJECTIVES: No study has explored whether availability of endoscopic retrograde cholangiopancreatography (ERCP) is...

Medicine

20 March 2024

Association between sex hormones and bone age in boys aged 9-18 years from China

J Cell Mol Med. 2024 Apr;28(7):e18181. doi: 10.1111/jcmm.18181.ABSTRACTThis study aimed to analyse the association between sex hormones and bone age (BA) in boys aged 9-18...

Medicine

20 March 2024

Modified Senning procedure in a patient with dextrocardia with left atrial isomerism and anomalous systemic venous drainage: a rare case report

Cardiol Young. 2024 Mar 20:1-5. doi: 10.1017/S1047951124000477. Online ahead of print.ABSTRACTThe atrial switch procedure by Senning or Mustard technique primarily aims in correcting parallel systemic...

Medicine

20 March 2024

Girls with idiopathic central precocious puberty did not display substatial changes in body mass index after treatment with gonadotropin-releasing hormone analogues

Acta Paediatr. 2024 Mar 20. doi: 10.1111/apa.17185. Online ahead of print.ABSTRACTAIM: To evaluate changes in body mass index (BMI) in girls during and after treatment...

Medicine

20 March 2024

Detection of occult thrombosis in individuals with Fontan circulation by cardiac MRI

Cardiol Young. 2024 Mar 20:1-6. doi: 10.1017/S1047951124000489. Online ahead of print.ABSTRACTOBJECTIVE: Identifying thrombus formation in Fontan circulation has been highly variable, with reports between 17...

Medicine

20 March 2024

AKAP12 Upregulation Associates With PDE8A to Accelerate Cardiac Dysfunction

Circ Res. 2024 Mar 20. doi: 10.1161/CIRCRESAHA.123.323655. Online ahead of print.ABSTRACTBACKGROUND: In heart failure, signaling downstream the β2-adrenergic receptor is critical. Sympathetic stimulation of β2-adrenergic...

Medicine

20 March 2024

Tiam1 regulates proliferation, invasion, and differentiation in neuroblastoma through the Tiam1/Rac1 signaling pathway

Neoplasma. 2024 Feb;71(1):37-47. doi: 10.4149/neo_2024_221217N1184. Epub 2024 Jan 23.ABSTRACTNeuroblastoma is the most common extracranial solid tumor in children. The purpose of the present study is...

Medicine

20 March 2024

Acute and chronic rhinosinusitis age characteristics

Vestn Otorinolaringol. 2024;89(1):64-72. doi: 10.17116/otorino20248901164.ABSTRACTChildren's and adults' rhinosinusitis are two diseases that have both similarities and differences in anatomy, epidemiology, causes, pathogenesis, diagnosis and treatment....

Medicine

20 March 2024

Clinical case of tuberculous otitis media in early childhood

Vestn Otorinolaringol. 2024;89(1):32-36. doi: 10.17116/otorino20248901132.ABSTRACTNowadays, the incidence of tuberculosis remains high all over the world, despite the vaccination, medical support, social policy. The main reasons...

Medicine

20 March 2024

Balloon dilation as an alternative to tracheotomy for acquired subglottic stenosis in children of the first year of life

Vestn Otorinolaringol. 2024;89(1):10-15. doi: 10.17116/otorino20248901110.ABSTRACTOBJECTIVE: To study the efficacy and safety of balloon dilation as the first choice method in the treatment of children of...

Personality Disorders

20 March 2024

Implementing a whole-of-service stepped care approach to personality disorder treatment: Impact of training and service redesign on clinician attitudes and skills

Personal Ment Health. 2024 Mar 19. doi: 10.1002/pmh.1612. Online ahead of print.ABSTRACTPersonality disorders are a highly prevalent mental health condition. Historically, clinician attitudes have been...

Neuroscience

20 March 2024

Long-Term Blood Pressure Reductions Following Catheter-Based Renal Denervation: A Systematic Review and Meta-Analysis

Hypertension. 2024 Mar 20. doi: 10.1161/HYPERTENSIONAHA.123.22314. Online ahead of print.ABSTRACTBACKGROUND: Renal denervation is a recognized adjunct therapy for hypertension with clinically significant blood pressure (BP)-lowering...

Data Science

20 March 2024

Persistence of collective memory of corporate bankruptcy events discussed on X (Twitter) is influenced by pre-bankruptcy public attention

Sci Rep. 2024 Mar 19;14(1):6552. doi: 10.1038/s41598-024-53758-x.ABSTRACTCollective attention and memory involving significant events can be quantitatively studied via social media data. Previous studies analyzed user...

Anorexia Nervosa

20 March 2024

Observational Study of Clinical Profiles and Management of Liver Abscess in Hospitalized Patients: A North Indian Tertiary Care Perspective

Cureus. 2024 Feb 18;16(2):e54401. doi: 10.7759/cureus.54401. eCollection 2024 Feb.ABSTRACTBackground Liver abscesses are a significant health concern, necessitating prompt diagnosis and appropriate management. Spontaneous liver abscesses...

Anorexia Nervosa

20 March 2024

Associations between nutritional intake, stress and hunger biomarkers, and anxiety and depression during the treatment of anorexia nervosa in adolescents and young adults

Eat Behav. 2023 Dec;51:101822. doi: 10.1016/j.eatbeh.2023.101822. Epub 2023 Oct 26.ABSTRACTAdolescents and young adults (AYA) with anorexia nervosa (AN) frequently have co-occurring anxiety and depression, which...

Anorexia Nervosa

20 March 2024

A case of surgical treatment for bronchial foreign bodies with obstructive pneumonia

Respirol Case Rep. 2024 Mar 19;12(3):e01325. doi: 10.1002/rcr2.1325. eCollection 2024 Mar.ABSTRACTChildren and older adults are prone to unintentional foreign body aspiration. A 69-year-old man with...

Anorexia Nervosa

20 March 2024

Thiamine deficiency as a cause of anorexia in terminally ill cancer patients: A case of possible gastrointestinal beriberi

Palliat Support Care. 2024 Mar 20:1-3. doi: 10.1017/S1478951524000415. Online ahead of print.ABSTRACTOBJECTIVES: Anorexia in cancer patients has a variety of causes and impairs patients' quality...

Anorexia Nervosa

20 March 2024

Trajectories and predictive factors of weight recovery in patients with anorexia nervosa completing treatment. A latent class mixed model approach

Eur Eat Disord Rev. 2024 Mar 19. doi: 10.1002/erv.3088. Online ahead of print.ABSTRACTBACKGROUND: Treatment of anorexia nervosa (AN) sometimes requires hospitalisation, which is often lengthy,...

Anorexia Nervosa

20 March 2024

Temperament impact on eating disorder symptoms and habit formation: a novel model to inform treatment

J Eat Disord. 2024 Mar 19;12(1):40. doi: 10.1186/s40337-024-00998-x.ABSTRACTBACKGROUND: Temperament has long been described as the biological dimension of personality. Due to advancing brain-imaging technology, our...

Anorexia Nervosa

20 March 2024

Families tackling adolescent anorexia nervosa: family wellbeing in family-based treatment or other interventions. A scoping review

Eat Weight Disord. 2024 Mar 20;29(1):20. doi: 10.1007/s40519-024-01641-z.ABSTRACTPURPOSE: Family-based treatment (FBT) has contributed significantly to the treatment of anorexia nervosa (AN) in young people (YP)....

Alcoholism

20 March 2024

Hedan tablet ameliorated non-alcoholic steatohepatitis by moderating NF-kappaB and lipid metabolism-related pathways via regulating hepatic metabolites

J Cell Mol Med. 2024 Apr;28(7):e18194. doi: 10.1111/jcmm.18194.ABSTRACTNon-alcoholic steatohepatitis (NASH) is a severe form of fatty liver disease. If not treated, it can lead to...

Alcoholism

20 March 2024

Effects of silymarin use on liver enzymes and metabolic factors in metabolic dysfunction-associated steatotic liver disease: a systematic review and meta-analysis

Can Liver J. 2024 Feb 26;7(1):40-53. doi: 10.3138/canlivj-2023-0021. eCollection 2024 Feb.ABSTRACTBACKGROUND: Fatty liver disease comprises a wide range of related liver disorders affecting mainly people...

Alcoholism

20 March 2024

Unleashing the potential of adipose organoids: A revolutionary approach to combat obesity-related metabolic diseases

Theranostics. 2024 Feb 25;14(5):2075-2098. doi: 10.7150/thno.93919. eCollection 2024.ABSTRACTObesity-related metabolic diseases, including obesity, diabetes, hyperlipidemia, and non-alcoholic fatty liver diseases pose a significant threat to health....

Alcoholism

20 March 2024

Genetic prediction of modifiable lifestyle factors for erectile dysfunction

Sex Med. 2024 Mar 18;12(1):qfae010. doi: 10.1093/sexmed/qfae010. eCollection 2024 Feb.ABSTRACTBACKGROUND: The causal relationship between certain lifestyle factors and erectile dysfunction (ED) is still uncertain.AIM: The...

Alcoholism

20 March 2024

Alcohol Withdrawal Severity Measures for Identifying Patients Requiring High-Intensity Care

Crit Care Explor. 2024 Mar 18;6(3):e1066. doi: 10.1097/CCE.0000000000001066. eCollection 2024 Mar.ABSTRACTOBJECTIVES: Alcohol withdrawal syndrome (AWS) may progress to require high-intensity care. Approaches to identify hospitalized...

Alcoholism

20 March 2024

Pulmonary Dysfunction in Patients with Cirrhosis of the Liver: A Study of Pulmonary Function Tests and Arterial Blood Gases

Int J Appl Basic Med Res. 2024 Jan-Mar;14(1):48-53. doi: 10.4103/ijabmr.ijabmr_367_23. Epub 2024 Feb 20.ABSTRACTBACKGROUND AND AIM: Respiratory complications in liver cirrhosis can occur due to...

Alcoholism

20 March 2024

Active Components of Pueraria lobata through the MAPK/ERK Signaling Pathway Alleviate Iron Overload in Alcoholic Liver Disease

Chem Biodivers. 2024 Mar 19:e202400005. doi: 10.1002/cbdv.202400005. Online ahead of print.ABSTRACTOBJECTIVE: To delve into the primary active ingredients and mechanism of Pueraria lobata for alleviating...

Alcoholism

20 March 2024

Gehua Jiejiu Dizhi decoction ameliorates alcoholic fatty liver in mice by regulating lipid and bile acid metabolism and with exertion of antioxidant stress based on 4DLabel-free quantitative proteomic study

J Tradit Chin Med. 2024 Apr;44(2):277-288. doi: 10.19852/j.cnki.jtcm.20231018.001.ABSTRACTOBJECTIVE: To analyze the effect and molecular mechanism of Gehua Jiejiu Dizhi decoction (, GJDD) on alcoholic fatty...

Alcoholism

20 March 2024

Exploring the role of genetic variations in NAFLD: implications for disease pathogenesis and precision medicine approaches

Eur J Med Res. 2024 Mar 20;29(1):190. doi: 10.1186/s40001-024-01708-8.ABSTRACTNon-alcoholic fatty liver disease (NAFLD) is one of the leading causes of chronic liver diseases, affecting more...

Alcoholism

20 March 2024

Inverse association between plasma chlordecone concentrations and progression of alcoholic liver fibrosis: the role of liver metabolism

Environ Health. 2024 Mar 20;23(1):30. doi: 10.1186/s12940-024-01054-6.ABSTRACTBACKGROUND AND AIMS: Chlordecone is a persistent organochlorinated insecticide, extensively used in the French West Indies and has been...

Autism

20 March 2024

Behavioural, developmental and psychological characteristics in children with germline PTEN mutations: a carer report study

J Intellect Disabil Res. 2024 Mar 20. doi: 10.1111/jir.13130. Online ahead of print.ABSTRACTBACKGROUND: PTEN is primarily known as a tumour suppressor gene. However, research describes...

Autism

20 March 2024

Validation of factor structure of the neurodevelopmental parent report for outcome monitoring in down syndrome: confirmatory factor analysis

Front Psychiatry. 2024 Mar 5;15:1293937. doi: 10.3389/fpsyt.2024.1293937. eCollection 2024.ABSTRACTINTRODUCTION: The Neurodevelopmental Parent Report for Outcome Monitoring (ND-PROM), initially developed to monitor developmental and behavioral functions...

Autism

20 March 2024

Diseases categorized as autoinflammatory keratinization diseases (AiKDs), and their pathologies and treatments

Nagoya J Med Sci. 2024 Feb;86(1):1-15. doi: 10.18999/nagjms.86.1.1.ABSTRACTWhole-exome and whole-genome sequencing have become widespread in approximately the last 15 years, and the predisposing factors and...

Autism

20 March 2024

Developmental outcome of electroencephalographic findings in SYNGAP1 encephalopathy

Front Cell Dev Biol. 2024 Mar 5;12:1321282. doi: 10.3389/fcell.2024.1321282. eCollection 2024.ABSTRACTSYNGAP1 haploinsufficiency results in a developmental and epileptic encephalopathy (DEE) causing generalized epilepsies accompanied by...

Autism

20 March 2024

Caregiver strain and its predictors among parents of autistic children: a cross-sectional study

J Child Adolesc Ment Health. 2024 Mar 20:1-13. doi: 10.2989/17280583.2023.2279637. Online ahead of print.ABSTRACTObjective: This study estimates the frequency and predictors of caregiver strain (CGS)...

Autism

20 March 2024

Recurrent ATP1A1 variant Gly903Arg causes developmental delay, intellectual disability, and autism

Ann Clin Transl Neurol. 2024 Mar 19. doi: 10.1002/acn3.51963. Online ahead of print.ABSTRACTATP1A1 encodes a sodium-potassium ATPase that has been linked to several neurological diseases....

Autism

20 March 2024

Cerebellar phenotypes in germline PTEN mutation carriers

Neuropathol Appl Neurobiol. 2024 Apr;50(2):e12970. doi: 10.1111/nan.12970.ABSTRACTPTEN hamartoma tumour syndrome (PHTS) comprises different hereditary conditions caused by germline PTEN mutations, predisposing to the development of...

Autism

20 March 2024

Human cytomegalovirus (CMV) dysregulates neurodevelopmental pathways in cerebral organoids

Commun Biol. 2024 Mar 19;7(1):340. doi: 10.1038/s42003-024-05923-1.ABSTRACTHuman cytomegalovirus (CMV) infection is the leading non-genetic aetiology of congenital malformation in developed countries, causing significant fetal neurological...

Autism

20 March 2024

Increased gene dosage of RFWD2 causes autistic-like behaviors and aberrant synaptic formation and function in mice

Mol Psychiatry. 2024 Mar 19. doi: 10.1038/s41380-024-02515-7. Online ahead of print.ABSTRACTAutism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired social interactions, communication deficits...

Education

20 March 2024

Is insufficient introspection a reason to terminate residency training? – Scrutinising introspection among residents who disputed dismissal

Med Teach. 2024 Mar 20:1-8. doi: 10.1080/0142159X.2024.2323175. Online ahead of print.ABSTRACTINTRODUCTION: Insufficient introspection as part of the 4I's model of medical professionalism (introspection, integrity, interaction,...

Education

20 March 2024

Physicians’ Knowledge of the Systematic ABCDE Approach in Riyadh, Saudi Arabia

J Multidiscip Healthc. 2024 Mar 15;17:1179-1188. doi: 10.2147/JMDH.S451527. eCollection 2024.ABSTRACTPURPOSE: To evaluate physicians' knowledge of the ABCDE (Airway, Breathing, Circulation, Disability, Exposure) approach components.METHODS: A...

Education

20 March 2024

Polymorphous Low-Grade Adenocarcinoma of the Salivary Glands – A Review

Niger Med J. 2022 Apr 25;62(2):49-53. eCollection 2021 Mar-Apr.ABSTRACTPolymorphous low-grade adenocarcinoma (PLGA) is a rare neoplasm with an indolent course that occurs mainly in minor...

Education

20 March 2024

Twelve Tips to Succeed as Health Profession Clinical Educator in Resource-Limited Settings

Adv Med Educ Pract. 2024 Mar 13;15:201-206. doi: 10.2147/AMEP.S453993. eCollection 2024.ABSTRACTHealth professions education is one of the pillars of academic medicine; however, clinical educators often...

Education

20 March 2024

Designing the Future of Medical Education: The EPA Framework as a Catalyst to Inform Family Planning and Reproductive Health Fellowship Training Program in Ethiopia Medical Education: An Exploratory Sequential Mixed Method Study

Adv Med Educ Pract. 2024 Mar 13;15:189-200. doi: 10.2147/AMEP.S438315. eCollection 2024.ABSTRACTINTRODUCTION: Entrustable Professional Activities (EPAs) are tasks or responsibilities within a specific field that can...

Education

20 March 2024

Medical Law and Medical School Curricula: A Systematic Review

Cureus. 2024 Feb 17;16(2):e54377. doi: 10.7759/cureus.54377. eCollection 2024 Feb.ABSTRACTHealth law plays a crucial role in the field of medicine, as it dictates appropriate practices, regulations,...

Education

20 March 2024

Challenge-Hindrance Stressors and Academic Engagement Among Medical Postgraduates in China: A Moderated Mediation Model

Psychol Res Behav Manag. 2024 Mar 13;17:1115-1128. doi: 10.2147/PRBM.S448844. eCollection 2024.ABSTRACTBACKGROUND: Improving academic engagement of medical postgraduates is crucial for enhancing the quality of learning...

Education

20 March 2024

Oncology Education in the Nigerian Medical Curriculum: A Cross-Sectional Review

Niger Med J. 2022 Apr 26;62(3):127-132. eCollection 2021 May-Jun.ABSTRACTBACKGROUND: The quality of a physician is arguably related to the depth and quality of medical education...

Education

20 March 2024

Development of a strategy for the expansion of online teaching at the University of Würzburg based on the experiences of lecturers and students in the pandemic years 2020/21

GMS J Med Educ. 2024 Feb 15;41(1):Doc12. doi: 10.3205/zma001667. eCollection 2024.ABSTRACTBACKGROUND: Owing to the COVID-19 pandemic, the summer of 2020 saw face-to-face teaching replaced by...

Education

20 March 2024

Infection prevention in medical education – results of a descriptive cross-sectional study in Germany

GMS J Med Educ. 2024 Feb 15;41(1):Doc4. doi: 10.3205/zma001659. eCollection 2024.ABSTRACTOBJECTIVE: The aim of the study was to assess the current curricular status of content...

ADHD

20 March 2024

Neuroenhancement and mental health in students from four faculties – a cross-sectional questionnaire study

GMS J Med Educ. 2024 Feb 15;41(1):Doc9. doi: 10.3205/zma001664. eCollection 2024.ABSTRACTBACKGROUND: Students face great challenges at the beginning of and during their studies. Competitive experience,...

ADHD

20 March 2024

Changes in real-world dispensing of ADHD stimulants in youth from 2019 to 2021 in California

Front Public Health. 2024 Mar 5;12:1302144. doi: 10.3389/fpubh.2024.1302144. eCollection 2024.ABSTRACTINTRODUCTION: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common pediatric neurobehavioral disorders in the U.S....

ADHD

20 March 2024

Longitudinal Associations Between Symptoms of ADHD and Life: Success From Emerging Adulthood to Early Middle Adulthood

J Atten Disord. 2024 Mar 19:10870547241239148. doi: 10.1177/10870547241239148. Online ahead of print.ABSTRACTOBJECTIVE: To expand on current adult ADHD literature by investigating the stability of ADHD...

ADHD

20 March 2024

Comprehensive analyses of neurodevelopmental outcomes and quality of life of children with biliary atresia

J Pediatr Gastroenterol Nutr. 2024 Mar;78(3):514-523. doi: 10.1002/jpn3.12071. Epub 2023 Dec 6.ABSTRACTOBJECTIVES: To holistically evaluate neurodevelopmental outcomes and quality of life (QOL) of Japanese patients...

ADHD

20 March 2024

5-HT_FAsTR: a versatile, label-free, high-throughput, fluorescence-based microplate assay to quantify serotonin transport and release

Sci Rep. 2024 Mar 19;14(1):6541. doi: 10.1038/s41598-024-56712-z.ABSTRACTThe neurotransmitter serotonin plays a pivotal role in mood and depression. It also acts as a vasoconstrictor within blood...

ADHD

20 March 2024

Individualized atomoxetine response and tolerability in children with ADHD receiving different dosage regimens: the need for CYP2D6 genotyping and therapeutic drug monitoring to dance together

Transl Psychiatry. 2024 Mar 19;14(1):151. doi: 10.1038/s41398-024-02859-2.ABSTRACTIntegrating CYP2D6 genotyping and therapeutic drug monitoring (TDM) is crucial for guiding individualized atomoxetine therapy in children with attention-deficit/hyperactivity...

ADHD

20 March 2024

Suboptimal decision making and interpersonal problems in ADHD: longitudinal evidence from a laboratory task

Sci Rep. 2024 Mar 19;14(1):6535. doi: 10.1038/s41598-024-57041-x.ABSTRACTOver half of children with Attention-Deficit/Hyperactivity Disorder (ADHD) display interpersonal and social problems. Several lines of research suggest that...

ADHD

20 March 2024

Entrepreneurial mental health in the wake of COVID-19 in China with an emphasis on attention deficit hyperactivity disorder (ADHD) and dyslexia analysis

Sci Rep. 2024 Mar 19;14(1):6573. doi: 10.1038/s41598-024-56981-8.ABSTRACTThe COVID-19 pandemic has precipitated a global mental health crisis, with a particularly pronounced impact on the entrepreneurial sector....

Dementia

20 March 2024

The complement system in neurodegenerative diseases

Clin Sci (Lond). 2024 Mar 20;138(6):387-412. doi: 10.1042/CS20230513.ABSTRACTComplement is an important component of innate immune defence against pathogens and crucial for efficient immune complex disposal....

Dementia

20 March 2024

Psychometric properties of the Russian version of the Edinburgh cognitive and behavioral amyotrophic lateral sclerosis screen

Amyotroph Lateral Scler Frontotemporal Degener. 2024 Mar 20:1-3. doi: 10.1080/21678421.2024.2328579. Online ahead of print.ABSTRACTBACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative condition with observable cognitive...

Dementia

20 March 2024

“How will we cope?” Couples with intellectual disability where one partner has a diagnosis of dementia

Gerontologist. 2024 Mar 20:gnae030. doi: 10.1093/geront/gnae030. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: People with intellectual disability are at increased risk of dementia at an earlier...

Dementia

20 March 2024

Evidence based on Mendelian randomization and colocalization analysis strengthens causal relationships between structural changes in specific brain regions and risk of amyotrophic lateral sclerosis

Front Neurosci. 2024 Mar 5;18:1333782. doi: 10.3389/fnins.2024.1333782. eCollection 2024.ABSTRACTBACKGROUND: Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by the degeneration of motor neurons in...

Dementia

20 March 2024

Editorial: Effects of vascular function and aging on brain circulation and neurodegeneration

Front Aging. 2024 Mar 5;5:1385066. doi: 10.3389/fragi.2024.1385066. eCollection 2024.NO ABSTRACTPMID:38505646 | PMC:PMC10948611 | DOI:10.3389/fragi.2024.1385066

Dementia

20 March 2024

Clinical outcomes in patients with neurological disorders following periacetabular tumor removal and endoprosthetic reconstruction of the hemipelvis

Front Surg. 2024 Mar 5;11:1279179. doi: 10.3389/fsurg.2024.1279179. eCollection 2024.ABSTRACTBACKGROUND: Surgical treatment of musculoskeletal tumors in the periacetabular region present extremely difficult due to the complex...

Dementia

20 March 2024

The impact of postoperative agitated delirium on dementia in surgical patients

Brain Commun. 2024 Mar 19;6(2):fcae076. doi: 10.1093/braincomms/fcae076. eCollection 2024.ABSTRACTThis study investigates the association between postoperative agitated delirium and the risk of dementia in patients who...

Dementia

20 March 2024

Associations between vascular health, brain stiffness and global cognitive function

Brain Commun. 2024 Feb 29;6(2):fcae073. doi: 10.1093/braincomms/fcae073. eCollection 2024.ABSTRACTVascular brain injury results in loss of structural and functional connectivity and leads to cognitive impairment. Its...

Dementia

20 March 2024

Racial and ethnic differences in disease course Medicare expenditures for beneficiaries with dementia

J Am Geriatr Soc. 2024 Mar 20. doi: 10.1111/jgs.18822. Online ahead of print.ABSTRACTBACKGROUND: Research on racial and ethnic disparities in costs of care during the...

Dementia

20 March 2024

Assessment of Mild Cognitive Impairment Using CogEvo: A Computerized Cognitive Function Assessment Tool

J Prim Care Community Health. 2024 Jan-Dec;15:21501319241239228. doi: 10.1177/21501319241239228.ABSTRACTINTRODUCTION/OBJECTIVES: To assess the utility of the computerized cognitive function assessment tool, CogEvo, as a screening tool...

Suicide

20 March 2024

Burn Patients and Mental Health: A Matched Cohort Study

Ann Surg. 2024 Mar 20. doi: 10.1097/SLA.0000000000006270. Online ahead of print.ABSTRACTOBJECTIVE: To determine the association between burns and hospitalization for mental health disorders up to...

Suicide

20 March 2024

Social Support, Psychological Strain, and Suicidality: Evidence from Chinese Universities

Psychol Sch. 2024 Jan;61(1):205-219. doi: 10.1002/pits.23047. Epub 2023 Aug 12.ABSTRACTThis study aimed to apply psychological strain theory to explore the relationship between psychological strain and...

Suicide

20 March 2024

Case report: Organ donation after euthanasia for psychiatric suffering: some of the practical and ethical lessons Martijn taught us

Front Psychiatry. 2024 Mar 5;15:1234741. doi: 10.3389/fpsyt.2024.1234741. eCollection 2024.ABSTRACTEuthanasia in psychiatric patients presents unique challenges, especially when combined with organ donation. In this article, the...

PTSD

20 March 2024

Validating the efficacy and value proposition of mental fitness vocal biomarkers in a psychiatric population: prospective cohort study

Front Psychiatry. 2024 Mar 5;15:1342835. doi: 10.3389/fpsyt.2024.1342835. eCollection 2024.ABSTRACTBACKGROUND: The utility of vocal biomarkers for mental health assessment has gained increasing attention. This study aims...

PTSD

20 March 2024

Post-traumatic stress disorder in a national sample of preadolescent children 9 to 10 years old: Prevalence, correlates, clinical sequelae, and treatment utilization

Transl Psychiatry. 2024 Mar 19;14(1):152. doi: 10.1038/s41398-024-02868-1.ABSTRACTAlthough posttraumatic stress disorder (PTSD) has been well characterized in adults, its epidemiology in children is unclear. The current...

Psychosis

20 March 2024

Longitudinal association of social isolation and loneliness with physical function among in-patients living with schizophrenia

J Psychiatr Ment Health Nurs. 2024 Mar 20. doi: 10.1111/jpm.13043. Online ahead of print.ABSTRACTWHAT IS KNOWN ON THE SUBJECT?: People living with schizophrenia have reduced...

Psychosis

20 March 2024

Additive effects of a family history of schizophrenia spectrum disorders and an environmental risk score for the outcome of patients with non-affective first-episode psychosis

Psychol Med. 2024 Mar 20:1-9. doi: 10.1017/S0033291724000576. Online ahead of print.ABSTRACTBACKGROUND: First-episode psychotic disorders comprise a heterogeneous phenotype with a complex etiology involving numerous common...

Psychosis

20 March 2024

Potential Dextromethorphan-Induced Serotonin Syndrome Leading to Homicide and Suicide

Acad Forensic Pathol. 2024 Jan 30;14(1):21-25. doi: 10.1177/19253621231224531. eCollection 2024 Mar.ABSTRACTLimited case reports have been published regarding serotonin syndrome due to the combined effects of...

Psychosis

20 March 2024

The effectiveness of the community reinforcement approach (CRA) in the context of quality of life and happiness among people using drugs

Front Public Health. 2024 Mar 5;12:1229262. doi: 10.3389/fpubh.2024.1229262. eCollection 2024.ABSTRACTINTRODUCTION: The Community Reinforcement Approach is an evidence-based treatment modality for alcohol and drug addiction treatment...

Psychosis

20 March 2024

The gender-affirming model of care is incompatible with competent, ethical medical practice

Australas Psychiatry. 2024 Mar 19:10398562241239478. doi: 10.1177/10398562241239478. Online ahead of print.ABSTRACTOBJECTIVE: To examine the compatibility of gender-affirming care with the principles and practices of psychiatry.CONCLUSIONS:...

Psychosis

20 March 2024

Introducing neurofilament light chain measure in psychiatry: current evidence, opportunities, and pitfalls

Mol Psychiatry. 2024 Mar 19. doi: 10.1038/s41380-024-02524-6. Online ahead of print.ABSTRACTThe recent introduction of new-generation immunoassay methods allows the reliable quantification of structural brain markers...

Psychosis

20 March 2024

Effect of olanzapine exposure on relapse and brain structure in patients with major depressive disorder with psychotic features

Mol Psychiatry. 2024 Mar 19. doi: 10.1038/s41380-024-02523-7. Online ahead of print.ABSTRACTSome data suggest that antipsychotics may adversely affect brain structure. We examined the relationship among...

Psychosis

20 March 2024

Data-driven, connectome-wide analysis identifies psychosis-specific brain correlates of fear and anxiety

Mol Psychiatry. 2024 Mar 19. doi: 10.1038/s41380-024-02512-w. Online ahead of print.ABSTRACTDecades of psychosis research highlight the prevalence and the clinical significance of negative emotions, such...

Psychosis

20 March 2024

Discontinuation of psychotropic medication: a synthesis of evidence across medication classes

Mol Psychiatry. 2024 Mar 19. doi: 10.1038/s41380-024-02445-4. Online ahead of print.ABSTRACTPharmacotherapy is an effective treatment modality across psychiatric disorders. Nevertheless, many patients discontinue their medication...

Psychosis

20 March 2024

The revised Psychosis Attachment Measure: further psychometric evidence

Soc Psychiatry Psychiatr Epidemiol. 2024 Mar 19. doi: 10.1007/s00127-024-02624-2. Online ahead of print.ABSTRACTPURPOSE: Disorganised attachment is a key concept in understanding the development of psychosis....

Artificial Intelligence

20 March 2024

Deus Ex Machina? The Rise of Artificial Intelligence in Toxicology

Chem Res Toxicol. 2024 Mar 20. doi: 10.1021/acs.chemrestox.4c00050. Online ahead of print.ABSTRACTArtificial intelligence (AI) is rising rapidly, driven by big data, complex algorithms, and computing...

Artificial Intelligence

20 March 2024

Artificial Intelligence/Machine Learning: The New Frontier of Clinical Pharmacology and Precision Medicine

Clin Pharmacol Ther. 2024 Apr;115(4):637-642. doi: 10.1002/cpt.3198.NO ABSTRACTPMID:38505955 | DOI:10.1002/cpt.3198

Artificial Intelligence

20 March 2024

Artificial Intelligence in Bone Metastasis Imaging: Recent Progresses from Diagnosis to Treatment – A Narrative Review

Crit Rev Oncog. 2024;29(2):77-90. doi: 10.1615/CritRevOncog.2023050470.ABSTRACTThe introduction of artificial intelligence (AI) represents an actual revolution in the radiological field, including bone lesion imaging. Bone lesions...

Artificial Intelligence

20 March 2024

Radiomics and Artificial Intelligence in Renal Lesion Assessment

Crit Rev Oncog. 2024;29(2):65-75. doi: 10.1615/CritRevOncog.2023051084.ABSTRACTRadiomics, the extraction and analysis of quantitative features from medical images, has emerged as a promising field in radiology with...

Artificial Intelligence

20 March 2024

The Role of Artificial Intelligence and Texture Analysis in Interventional Radiological Treatments of Liver Masses: A Narrative Review

Crit Rev Oncog. 2024;29(2):37-52. doi: 10.1615/CritRevOncog.2023049855.ABSTRACTLiver lesions, including both benign and malignant tumors, pose significant challenges in interventional radiological treatment planning and prognostication. The emerging...

Artificial Intelligence

20 March 2024

Adoption of AI in Oncological Imaging: Ethical, Regulatory, and Medical-Legal Challenges

Crit Rev Oncog. 2024;29(2):29-35. doi: 10.1615/CritRevOncog.2023050584.ABSTRACTArtificial Intelligence (AI) algorithms have shown great promise in oncological imaging, outperforming or matching radiologists in retrospective studies, signifying their...

Artificial Intelligence

20 March 2024

Exploring the Potential of Artificial Intelligence in Breast Ultrasound

Crit Rev Oncog. 2024;29(2):15-28. doi: 10.1615/CritRevOncog.2023048873.ABSTRACTBreast ultrasound has emerged as a valuable imaging modality in the detection and characterization of breast lesions, particularly in women...

Artificial Intelligence

20 March 2024

Artificial Intelligence in Lung Cancer Imaging: From Data to Therapy

Crit Rev Oncog. 2024;29(2):1-13. doi: 10.1615/CritRevOncog.2023050439.ABSTRACTLung cancer remains a global health challenge, leading to substantial morbidity and mortality. While prevention and early detection strategies have...

Artificial Intelligence

20 March 2024

Preface: Artificial Intelligence and the Revolution of Oncological Imaging

Crit Rev Oncog. 2024;29(2):ix-xi. doi: 10.1615/CritRevOncog.v29.i2.30.NO ABSTRACTPMID:38505876 | DOI:10.1615/CritRevOncog.v29.i2.30

Artificial Intelligence

20 March 2024

AI in Pharma: Transforming Drug Discovery and Strategic Management with MYC-Modulating Compounds and BET Protein Inhibitors

ACS Med Chem Lett. 2024 Feb 13;15(3):334-336. doi: 10.1021/acsmedchemlett.4c00057. eCollection 2024 Mar 14.ABSTRACTThe landscape of pharmaceutical R&D is being reshaped by the synergistic integration of...

Oxford University News

20 March 2024

World Happiness Report offers most comprehensive picture yet of happiness across generations

Fresh insights from the World Happiness Report 2024 paint the richest picture yet of happiness trends across different ages and generations.

Anxiety

20 March 2024

The role of momentary emotions in promoting error learning orientation among lower secondary school students: An intervention study embedded in a short visual programming course

Br J Educ Psychol. 2024 Mar 19. doi: 10.1111/bjep.12681. Online ahead of print.ABSTRACTBACKGROUND: Students make many errors in visual programming. In order to learn from...

Medicine

20 March 2024

Oral Structural Dysphagia in Children

Otolaryngol Clin North Am. 2024 Mar 18:S0030-6665(24)00025-2. doi: 10.1016/j.otc.2024.02.012. Online ahead of print.ABSTRACTOral causes of dysphagia in infancy may involve the lips, the tongue, or...

Medicine

20 March 2024

Vaccine value profile for Klebsiella pneumoniae

Vaccine. 2024 Mar 18:S0264-410X(24)00248-2. doi: 10.1016/j.vaccine.2024.02.072. Online ahead of print.ABSTRACTKlebsiella pneumoniae causes community- and healthcare-associated infections in children and adults. Globally in 2019, an estimated...

Medicine

20 March 2024

Diagnosis and management of anemia in pediatric inflammatory bowel diseases: Clinical practice guidelines on behalf of the SIGENP IBD Working group

Dig Liver Dis. 2024 Mar 18:S1590-8658(24)00277-9. doi: 10.1016/j.dld.2024.02.016. Online ahead of print.ABSTRACTAnemia is one of the most frequent extra-intestinal manifestations of inflammatory bowel disease. Insidious...

Medicine

20 March 2024

Puzzling phenomenon: adult-onset cancer predisposition and pediatric cancer

Trends Cancer. 2024 Mar 18:S2405-8033(24)00049-9. doi: 10.1016/j.trecan.2024.02.011. Online ahead of print.ABSTRACTPathogenic variants (PVs) in DNA repair-linked adult-onset cancer predisposition genes, including double heterozygosity, are increasingly...

Medicine

20 March 2024

Implementation of a novel form of care for the early detection and prevention of emotional and behavioral problems in children in the pediatric setting: Qualitative interviews with pediatricians, practice staff and parents

Z Evid Fortbild Qual Gesundhwes. 2024 Mar 18:S1865-9217(24)00002-3. doi: 10.1016/j.zefq.2023.12.004. Online ahead of print.ABSTRACTAIM OF THE STUDY: Evaluation of the implementation of a standardized screening...

Medicine

20 March 2024

Long-term clinical outcomes and management of hypertriglyceridemia in children with Apo-CII deficiency

Nutr Metab Cardiovasc Dis. 2024 Feb 17:S0939-4753(24)00077-2. doi: 10.1016/j.numecd.2024.02.006. Online ahead of print.ABSTRACTBACKGROUND AND AIM: APO CII, one of several cofactors which regulate lipoprotein lipase...

Medicine

20 March 2024

Prenatal cannabis use disorder and gastroschisis in California, 2007-19

Int J Epidemiol. 2024 Feb 14;53(2):dyae042. doi: 10.1093/ije/dyae042.ABSTRACTBACKGROUND: Gastroschisis is a congenital anomaly of the abdominal wall with an unknown aetiology. Recent trends in the...

Psychiatry

20 March 2024

Circuit-based neuromodulation enhances delayed recall in amnestic mild cognitive impairment

J Neurol Neurosurg Psychiatry. 2024 Mar 19:jnnp-2023-333152. doi: 10.1136/jnnp-2023-333152. Online ahead of print.ABSTRACTBACKGROUND: This study aimed to investigate the efficacy of circuits-based paired associative stimulation...

Psychiatry

20 March 2024

Efficacy and safety of pharmacological treatment of psoriatic arthritis: a systematic literature research informing the 2023 update of the EULAR recommendations for the management of psoriatic arthritis

Ann Rheum Dis. 2024 Mar 19:ard-2024-225534. doi: 10.1136/ard-2024-225534. Online ahead of print.ABSTRACTOBJECTIVES: To obtain an overview of recent evidence on efficacy and safety of pharmacological...

Medicine

20 March 2024

Presence and utility of electrocardiographic abnormalities in long-term childhood cancer survivors

Heart. 2024 Mar 19:heartjnl-2023-323474. doi: 10.1136/heartjnl-2023-323474. Online ahead of print.ABSTRACTBACKGROUND: We assessed the prevalence and diagnostic value of ECG abnormalities for cardiomyopathy surveillance in childhood...

Medicine

20 March 2024

Doxapram for apnea of prematurity – the importance of maintaining equipoise

Arch Dis Child Fetal Neonatal Ed. 2024 Mar 19:fetalneonatal-2024-327012. doi: 10.1136/archdischild-2024-327012. Online ahead of print.NO ABSTRACTPMID:38503483 | DOI:10.1136/archdischild-2024-327012

Medicine

20 March 2024

Prevalence of strabismus and risk factors in adults born preterm with and without retinopathy of prematurity: results from the Gutenberg Prematurity Eye study

Br J Ophthalmol. 2024 Mar 19:bjo-2023-324698. doi: 10.1136/bjo-2023-324698. Online ahead of print.ABSTRACTAIM: The purpose of this study was to assess the prevalence of strabismus and...

Autism

20 March 2024

Piloting a Community-Based, Culturally Adapted Health Promotion Program for Children with Autism Spectrum Disorder and Developmental Disabilities in First-Generation Korean Immigrant Families

Health Soc Work. 2024 Mar 19:hlae008. doi: 10.1093/hsw/hlae008. Online ahead of print.ABSTRACTChildren with autism spectrum disorder and developmental disabilities (ASD/DD) face barriers to participation in...

Autism

20 March 2024

Correction: Can we distinguish the consequences of early maltreatment on child behaviour from idiopathic autism?

Arch Dis Child. 2024 Mar 19;109(4):e3. doi: 10.1136/archdischild-2022-324156corr1.NO ABSTRACTPMID:38503441 | DOI:10.1136/archdischild-2022-324156corr1

Autism

20 March 2024

Mono-allelic KCNB2 variants lead to a neurodevelopmental syndrome caused by altered channel inactivation

Am J Hum Genet. 2024 Mar 13:S0002-9297(24)00046-6. doi: 10.1016/j.ajhg.2024.02.014. Online ahead of print.ABSTRACTIon channels mediate voltage fluxes or action potentials that are central to the...

Autism

20 March 2024

Early-life exposure to PM2.5 leads to ASD-like phenotype in male offspring rats through activation of PI3K-AKT signaling pathway

Ecotoxicol Environ Saf. 2024 Mar 18;274:116222. doi: 10.1016/j.ecoenv.2024.116222. Online ahead of print.ABSTRACTPrevious studies have shown that early-life exposure to fine particulate matter (PM2.5) is associated...

Self Harm

20 March 2024

Measurement properties of tools used to assess self-harm in autistic and general population adults

Clin Psychol Rev. 2024 Mar 12;109:102412. doi: 10.1016/j.cpr.2024.102412. Online ahead of print.ABSTRACTAutistic people are at increased risk of experiencing self-harm compared to the general population....

Forensic Psychiatry

20 March 2024

Mindfulness-based cognitive therapy neurobiology in treatment-resistant obsessive-compulsive disorder: A domain-related resting-state networks approach

Eur Neuropsychopharmacol. 2024 Mar 18;82:72-81. doi: 10.1016/j.euroneuro.2024.02.011. Online ahead of print.ABSTRACTMindfulness-based cognitive therapy (MBCT) stands out as a promising augmentation psychological therapy for patients with...

Bulimia Nervosa

20 March 2024

Established and emerging treatments for eating disorders

Trends Mol Med. 2024 Mar 18:S1471-4914(24)00034-0. doi: 10.1016/j.molmed.2024.02.009. Online ahead of print.ABSTRACTEating disorders (EDs) are common mental health conditions that carry exceedingly high morbidity and...

Bipolar Disorder

20 March 2024

Managing the Dual Diagnosis Dilemma of Bipolar Disorder and Substance Abuse in Clinical Settings

J Dual Diagn. 2024 Mar 19:1-10. doi: 10.1080/15504263.2024.2328600. Online ahead of print.ABSTRACTObjective: Drug addiction is a chronic mental disorder that significantly impacts all aspects of...

Anxiety

20 March 2024

Geographic differences in psychological symptoms, sleep quality, and quality of life in patients with inflammatory bowel disease: A multicenter study in China

J Dig Dis. 2024 Mar 19. doi: 10.1111/1751-2980.13259. Online ahead of print.ABSTRACTOBJECTIVE: We aimed to explore the geographic differences in psychological symptoms, sleep quality, and...

Anxiety

20 March 2024

Consequences of the Coronavirus disease 2019 pandemic on child and adolescent mental, psychosocial, and physical health: A scoping review and interactive evidence map

J Child Health Care. 2024 Mar 19:13674935241238794. doi: 10.1177/13674935241238794. Online ahead of print.ABSTRACTEffects of the Coronavirus disease 2019 (COVID-19) pandemic on children stem beyond immediate...

Anxiety

20 March 2024

Geographical variation in perceptions, attitudes and barriers to mental health care-seeking across the UK: a cross-sectional study

BMJ Open. 2024 Mar 18;14(3):e073731. doi: 10.1136/bmjopen-2023-073731.ABSTRACTOBJECTIVES: To examine the relative importance of the drivers of mental health care-seeking intention and how these, along with...

Anxiety

20 March 2024

Effectiveness of virtual reality on pain and anxiety in patients undergoing cardiac procedures: a systematic review and meta-analysis of randomized controlled trials

Curr Probl Cardiol. 2024 Mar 17:102532. doi: 10.1016/j.cpcardiol.2024.102532. Online ahead of print.ABSTRACTBACKGROUND: Cardiac procedures often induce pain and anxiety in patients, adversely impacting recovery. Pharmachological...

Addiction

20 March 2024

Tobacco control policy and regulation from diverse perspectives and contexts

Tob Control. 2024 Mar 19;33(e1):e1-e2. doi: 10.1136/tc-2024-058662.NO ABSTRACTPMID:38503442 | DOI:10.1136/tc-2024-058662

Schizophrenia

20 March 2024

Schizophrenia and epileptic comorbidity

Rev Neurol (Paris). 2024 Mar 18:S0035-3787(24)00473-9. doi: 10.1016/j.neurol.2024.03.002. Online ahead of print.ABSTRACTEpileptic seizures have been widely considered as a complication of external or iatrogenic factors...

Psychiatry

20 March 2024

Participant Fraud in Virtual Qualitative Substance Use Research: Recommendations and Considerations for Detection and Prevention Based on a Case Study

Subst Use Misuse. 2024 Mar 19:1-10. doi: 10.1080/10826084.2024.2330892. Online ahead of print.ABSTRACTBackground: The COVID-19 pandemic has accelerated and amplified the use of virtual research methods....

Neuroscience

20 March 2024

Global Crisis and Mental Health and Well-Being of Older Adults

Am J Geriatr Psychiatry. 2024 Apr;32(4):409-411. doi: 10.1016/j.jagp.2023.10.021. Epub 2024 Feb 15.NO ABSTRACTPMID:38503541 | DOI:10.1016/j.jagp.2023.10.021

Neuroscience

20 March 2024

Schwann Cell Development and Myelination

Cold Spring Harb Perspect Biol. 2024 Mar 19:a041360. doi: 10.1101/cshperspect.a041360. Online ahead of print.ABSTRACTGlial cells in the peripheral nervous system (PNS), which arise from the...

Neuroscience

20 March 2024

Regulators of Oligodendrocyte Differentiation

Cold Spring Harb Perspect Biol. 2024 Mar 19:a041358. doi: 10.1101/cshperspect.a041358. Online ahead of print.ABSTRACTMyelination has evolved as a mechanism to ensure fast and efficient propagation...

Neuroscience

20 March 2024

Intrinsic and synaptic contributions to repetitive spiking in dentate granule cells

J Neurosci. 2024 Mar 19:e0716232024. doi: 10.1523/JNEUROSCI.0716-23.2024. Online ahead of print.ABSTRACTRepetitive firing of granule cells (GCs) in the dentate gyrus facilitates synaptic transmission to the...

Neuroscience

20 March 2024

Effect of Natural Osmolytes on Recombinant Tau Monomer: Propensity of Oligomerization and Aggregation

ACS Chem Neurosci. 2024 Mar 19. doi: 10.1021/acschemneuro.3c00614. Online ahead of print.ABSTRACTThe pathological misfolding and aggregation of the microtubule associated protein tau (MAPT), a full...

Neuroscience

20 March 2024

Discontinuity third harmonic generation microscopy for label-free imaging and quantification of intraepidermal nerve fibers

Cell Rep Methods. 2024 Mar 13:100735. doi: 10.1016/j.crmeth.2024.100735. Online ahead of print.ABSTRACTLabel-free imaging methodologies for nerve fibers rely on spatial signal continuity to identify fibers...

Neuroscience

20 March 2024

Novel RAB39B loss-of-function mutation in patient with typical early-onset Parkinson’s disease

Parkinsonism Relat Disord. 2024 Feb 13;123:106038. doi: 10.1016/j.parkreldis.2024.106038. Online ahead of print.ABSTRACTRAB39B mutations have been identified in X-linked developmental delays. Recently, RAB39B mutations were identified...

Anorexia Nervosa

20 March 2024

The current sociocultural background of eating disorders

Trends Mol Med. 2024 Mar 18:S1471-4914(24)00035-2. doi: 10.1016/j.molmed.2024.02.010. Online ahead of print.ABSTRACTEating disorders (EDs) are complex phenomena that are partly influenced by sociocultural factors. The...

Alcoholism

20 March 2024

Ablation of secreted phosphoprotein-1 in hepatocytes increases fatty acid oxidation and ameliorates alcohol-associated liver disease

Alcohol Clin Exp Res (Hoboken). 2024 Mar 19. doi: 10.1111/acer.15304. Online ahead of print.ABSTRACTBACKGROUND: Previously, we demonstrated that Spp1-/- mice exhibit a greater susceptibility to...

Alcoholism

20 March 2024

Reduced production of Ethyl Carbamate in wine by regulating the accumulation of arginine in Saccharomyces cerevisiae

J Biotechnol. 2024 Mar 17:S0168-1656(24)00076-2. doi: 10.1016/j.jbiotec.2024.03.006. Online ahead of print.ABSTRACTEthyl carbamate (EC), a multisite carcinogenic compound, is naturally produced from urea and ethanol in...

Alcoholism

20 March 2024

Healthy Lifestyle and the Risk of Metabolic Dysfunction-Associated Fatty Liver Disease: A Large Prospective Cohort Study

Diabetes Metab J. 2024 Mar 19. doi: 10.4093/dmj.2023.0133. Online ahead of print.ABSTRACTBACKGROUND: The incidence density of metabolic dysfunction-associated fatty liver disease (MAFLD) and the effect...

Alcoholism

20 March 2024

From inspection to analysis: A combined approach to identifying counterfeit whiskeys using HS-GC-FID and bottle integrity

Forensic Sci Int. 2024 Mar 5;357:111977. doi: 10.1016/j.forsciint.2024.111977. Online ahead of print.ABSTRACTCounterfeiting of alcoholic beverages, particularly high-value spirits such as whiskey, presents significant challenges for...

Alcoholism

20 March 2024

Analysis of the therapeutic potential of miR-124 and miR-16 in non-alcoholic fatty liver disease

J Diabetes Complications. 2024 Mar 12;38(4):108722. doi: 10.1016/j.jdiacomp.2024.108722. Online ahead of print.ABSTRACTBACKGROUNDS: Non-alcoholic fatty liver disease (NAFLD) is a common condition affecting >25 % of...

Education

20 March 2024

Modelling the economic constraints and consequences of Anaesthesia Associate expansion in the UK. Response from the Association of Anaesthetists Trainee Committee to Br J Anaesth 2024

Br J Anaesth. 2024 Mar 18:S0007-0912(24)00090-4. doi: 10.1016/j.bja.2024.02.014. Online ahead of print.NO ABSTRACTPMID:38503623 | DOI:10.1016/j.bja.2024.02.014

Education

20 March 2024

Trends in gastric surgery operative experience among general surgery residents in the United States: A nationwide retrospective analysis

Surgery. 2024 Mar 18:S0039-6060(24)00075-8. doi: 10.1016/j.surg.2024.02.012. Online ahead of print.ABSTRACTBACKGROUND: Gastric surgery is a crucial component of general surgery training. However, there is a paucity...

Education

20 March 2024

Crowdsourcing a diagnosis? Exploring the accuracy of the size and type of group diagnosis: an experimental study

BMJ Qual Saf. 2024 Mar 19:bmjqs-2023-016695. doi: 10.1136/bmjqs-2023-016695. Online ahead of print.ABSTRACTBACKGROUND: The consultation process, where a clinician seeks an opinion from another clinician, is...

Education

20 March 2024

Unlocking bacterial defense: Exploring the potent inhibition of NorA efflux pump by coumarin derivatives in Staphylococcus aureus

Microb Pathog. 2024 Mar 17:106608. doi: 10.1016/j.micpath.2024.106608. Online ahead of print.ABSTRACTThe occurrence of bacterial resistance has been increasing, compromising the treatment of various infections. The...

Education

20 March 2024

‘Good’ evaluation: Methodological diversity may be empress, but sound methods remain queen

Med Educ. 2024 Mar 19. doi: 10.1111/medu.15374. Online ahead of print.NO ABSTRACTPMID:38503325 | DOI:10.1111/medu.15374

Education

20 March 2024

When I say … active learning

Med Educ. 2024 Mar 19. doi: 10.1111/medu.15383. Online ahead of print.NO ABSTRACTPMID:38503311 | DOI:10.1111/medu.15383

Education

20 March 2024

Changes over time in the course of advanced pancreatic cancer treatment with systemic chemotherapy: a pooled analysis of five clinical trials from two decades of the German AIO study group

ESMO Open. 2024 Mar 18;9(4):102944. doi: 10.1016/j.esmoop.2024.102944. Online ahead of print.ABSTRACTBACKGROUND: Over the past two decades, our group has conducted five multicenter trials focusing on...

Education

20 March 2024

Purdue Dean Willie Reed’s influence on veterinary medical education

J Am Vet Med Assoc. 2024 Apr 1;262(4):571. doi: 10.2460/javma.24.02.0101.NO ABSTRACTPMID:38503046 | DOI:10.2460/javma.24.02.0101

ADHD

20 March 2024

Distal-to-proximal etiologically relevant variables associated with the general (p) and specific factors of psychopathology

J Child Psychol Psychiatry. 2024 Mar 19. doi: 10.1111/jcpp.13979. Online ahead of print.ABSTRACTBACKGROUND: The general factor of psychopathology, often denoted as p, captures the common...

Dementia

20 March 2024

Requesting That Delirium Achieve Parity With Acute Encephalopathy in the MS-DRG System

J Acad Consult Liaison Psychiatry. 2024 Feb 22:S2667-2960(24)00024-7. doi: 10.1016/j.jaclp.2024.02.004. Online ahead of print.ABSTRACTSince 2007, the Medicare Severity Diagnosis Related Groups classification system has favored...

Dementia

20 March 2024

Dementia in Taiwan

Arch Gerontol Geriatr. 2024 Mar 16:105415. doi: 10.1016/j.archger.2024.105415. Online ahead of print.NO ABSTRACTPMID:38503624 | DOI:10.1016/j.archger.2024.105415

Dementia

20 March 2024

Migraine is a risk factor for pseudophakic positive dysphotopsia following monofocal lens implantation

Can J Ophthalmol. 2024 Mar 16:S0008-4182(24)00059-0. doi: 10.1016/j.jcjo.2024.02.010. Online ahead of print.ABSTRACTOBJECTIVE: To identify neuroadaptation-related risk factors for persistent positive dysphotopsia (>6 months) following monofocal...

Dementia

20 March 2024

Mitochondrial DNA deletions in the cerebrospinal fluid of patients with idiopathic REM sleep behaviour disorder

EBioMedicine. 2024 Mar 18;102:105065. doi: 10.1016/j.ebiom.2024.105065. Online ahead of print.ABSTRACTBACKGROUND: Idiopathic rapid eye movement (REM) sleep behaviour disorder (IRBD) represents the prodromal stage of Lewy...

Suicide

20 March 2024

Association between sleep quality, depressive symptoms, and suicidal ideation in college students

Psychol Health Med. 2024 Mar 19:1-19. doi: 10.1080/13548506.2024.2331491. Online ahead of print.ABSTRACTSuicide among college students is a challenging problem globally. Yet, the association between sleep...

Suicide

20 March 2024

Exploring the experiences of mental health nurses in the management of schizophrenia in the Upper East Region of Ghana: a qualitative study

BMJ Open. 2024 Mar 18;14(3):e079933. doi: 10.1136/bmjopen-2023-079933.ABSTRACTOBJECTIVE: Schizophrenia is a chronic condition, of which the diagnosis and management require comprehensive care. The role mental health...

PTSD

20 March 2024

Medical-surgical patients with untreated hazardous drinking: Randomized controlled trial of the DO-MoST intervention to improve health outcomes over 12-month follow-up

Drug Alcohol Depend. 2024 Mar 5;258:111259. doi: 10.1016/j.drugalcdep.2024.111259. Online ahead of print.ABSTRACTINTRODUCTION: High prevalence and harmful consequences of hazardous drinking among medical-surgical patients underscore the...

PTSD

20 March 2024

Heart rate reactivity during trauma recall as a predictor of treatment outcome in cognitive processing therapy for PTSD

Behav Res Ther. 2024 Mar 11;176:104519. doi: 10.1016/j.brat.2024.104519. Online ahead of print.ABSTRACTEmotional engagement when recollecting a trauma memory is considered a key element of effective...

PTSD

20 March 2024

Trauma film viewing and intrusive memories: Relationship between salivary alpha amylase, endocannabinoids, and cortisol

Psychoneuroendocrinology. 2024 Mar 8;164:107007. doi: 10.1016/j.psyneuen.2024.107007. Online ahead of print.ABSTRACTThe endogenous cannabinoid (ECB) system is a small molecule lipid signalling system that is involved in...

PTSD

20 March 2024

Impact of PTSD treatment on postconcussive symptoms in veterans: A comparison of sertraline, prolonged exposure, and their combination

J Psychiatr Res. 2024 Mar 8;173:64-70. doi: 10.1016/j.jpsychires.2024.03.011. Online ahead of print.ABSTRACTMany Veterans who served in Iraq and Afghanistan struggle with posttraumatic stress disorder (PTSD)...

Psychosis

20 March 2024

Home-based Intervention with Semaglutide Treatment of Neuroleptic-Related Prediabetes (HISTORI): protocol describing a prospective, randomised, placebo controlled and double-blinded multicentre trial

BMJ Open. 2024 Mar 18;14(3):e077173. doi: 10.1136/bmjopen-2023-077173.ABSTRACTINTRODUCTION: Subjects with schizophrenia have a 2-3 fold higher mortality rate than the general population and a reduced life...

Psychosis

20 March 2024

A detailed hierarchical model of psychopathology in Chinese clinical sample: Based on the SCL-90-R measure

J Affect Disord. 2024 Mar 17:S0165-0327(24)00462-2. doi: 10.1016/j.jad.2024.03.048. Online ahead of print.ABSTRACTOBJECTIVE: The Hierarchical Taxonomy of Psychopathology (HiTOP)model is an impressive effort to overcome shortcomings...

Psychosis

20 March 2024

Epidemiology of DSM-5 psychiatric disorders in Kenyan Youth with Low and High Psychosis Risk

Compr Psychiatry. 2024 Mar 11;131:152473. doi: 10.1016/j.comppsych.2024.152473. Online ahead of print.ABSTRACTINTRODUCTION: There are few psychiatric epidemiology studies among Kenyan youth and fewer among those at...

Artificial Intelligence

20 March 2024

Charting new AI education in gastroenterology: Cross-sectional evaluation of ChatGPT and perplexity AI in medical residency exam

Dig Liver Dis. 2024 Mar 18:S1590-8658(24)00302-5. doi: 10.1016/j.dld.2024.02.019. Online ahead of print.ABSTRACTBACKGROUND: Conversational chatbots, fueled by large language models, spark debate over their potential in...

Artificial Intelligence

20 March 2024

Development of an artificial intelligence system to improve cancer clinical trial eligibility screening

Bull Cancer. 2024 Mar 18:S0007-4551(24)00078-X. doi: 10.1016/j.bulcan.2024.01.010. Online ahead of print.ABSTRACTINTRODUCTION: The recruitment step of all clinical trials is time consuming, harsh and generate extra...

Artificial Intelligence

20 March 2024

Rammya Mathew: Could artificial intelligence be the key to transforming general practice?

BMJ. 2024 Mar 19;384:q661. doi: 10.1136/bmj.q661.NO ABSTRACTPMID:38503458 | DOI:10.1136/bmj.q661

Artificial Intelligence

20 March 2024

Anchored-fusion enables targeted fusion search in bulk and single-cell RNA sequencing data

Cell Rep Methods. 2024 Mar 12:100733. doi: 10.1016/j.crmeth.2024.100733. Online ahead of print.ABSTRACTHere, we present Anchored-fusion, a highly sensitive fusion gene detection tool. It anchors a...

Artificial Intelligence

20 March 2024

MedChatZH: A tuning LLM for traditional Chinese medicine consultations

Comput Biol Med. 2024 Mar 13;172:108290. doi: 10.1016/j.compbiomed.2024.108290. Online ahead of print.ABSTRACTGenerative Large Language Models (LLMs) have achieved significant success in various natural language processing...

Artificial Intelligence

20 March 2024

A new segmentation algorithm for peripapillary atrophy and optic disk from ultra-widefield Photographs1

Comput Biol Med. 2024 Mar 13;172:108281. doi: 10.1016/j.compbiomed.2024.108281. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVE: The prevalence of myopia and high myopia is increasing globally, underscoring...

Artificial Intelligence

20 March 2024

Dual-channel neural network for instance segmentation of synapse

Comput Biol Med. 2024 Mar 13;172:108298. doi: 10.1016/j.compbiomed.2024.108298. Online ahead of print.ABSTRACTDetection and segmentation of neural synapses in electron microscopy images are the committed steps...

Artificial Intelligence

20 March 2024

SYNDSURV: A simple framework for survival analysis with data distributed across multiple institutions

Comput Biol Med. 2024 Mar 15;172:108288. doi: 10.1016/j.compbiomed.2024.108288. Online ahead of print.ABSTRACTData sharing among different institutions represents one of the major challenges in developing distributed...

Artificial Intelligence

20 March 2024

US2Mask: Image-to-mask generation learning via a conditional GAN for cardiac ultrasound image segmentation

Comput Biol Med. 2024 Mar 15;172:108282. doi: 10.1016/j.compbiomed.2024.108282. Online ahead of print.ABSTRACTCardiac ultrasound (US) image segmentation is vital for evaluating clinical indices, but it often...

Artificial Intelligence

20 March 2024

Determining steady-state trough range in vancomycin drug dosing using machine learning

J Crit Care. 2024 Mar 18;82:154784. doi: 10.1016/j.jcrc.2024.154784. Online ahead of print.ABSTRACTBACKGROUND: Vancomycin is a renally eliminated, nephrotoxic, glycopeptide antibiotic with a narrow therapeutic window,...

Oxford Talks

20 March 2024

Empowering Tech Leaders

🌟 Our inspiring panellists include: 🔹 Soumaya Hamzaoui - COO & Co-founder of RedCloud, listed among the UK’s top 50 female entrepreneurs. Grew up in...

Oxford Talks

20 March 2024

Updates from the IOI with Sir Stewart Cole and Prof Craig Maclean

Sir Stewart Cole has recently joined the Ineos Oxford Institute for antimicrobial research as Executive Chair. In his role, Prof Cole will provide strategic oversight...

Oxford Talks

20 March 2024

Dissecting Parkinson’s disease with long-read RNA-sequencing

Accurate and complete human gene annotation, defined as the genetic coordinates of all transcripts of a given gene, is fundamental to a huge range of...

Real-Time AI PFDR Research

20 March 2024

Joseph Miller: Prevention of future deaths report

Date of report: 14/03/2024 Ref: 2024-0142 Deceased name: Joseph Miller Coroner name: Alison Mutch Coroner Area: Manchester South Category: Alcohol, drug and medication related deathsThis...

Real-Time AI PFDR Research

20 March 2024

Victor Costello: Prevention of future deaths report

Date of report: 14/03/2024 Ref: 2024-0141 Deceased name: Victor Costello Coroner name: Jo Wharton Coroner Area: Teesside and Hartlepool Category: Care Home Health related deathsThis...

Real-Time AI PFDR Research

20 March 2024

Alan Smith: Prevention of future deaths report

Date of report: 13/03/2024 Ref: 2024-0140 Deceased name: Alan Smith Coroner name: Alison Mutch Coroner Area: Manchester South Category: Hospital Death (Clinical Procedures and medical...

Real-Time AI PFDR Research

20 March 2024

Terence Sullivan: Prevention of future deaths report

Date of report: 13/03/2024 Ref: 2024-0139 Deceased name: Terence Sullivan Coroner name: David Reid Coroner Area: Worcestershire Category: Hospital Death (Clinical Procedures and medical management)...

Forensic Psychiatry

20 March 2024

Emerging Roles of UDP-GalNAc Polypeptide N-Acetylgalactosaminyltransferases in Cardiovascular Disease

Aging Dis. 2024 Mar 14. doi: 10.14336/AD.2024.0308. Online ahead of print.ABSTRACTUDP-GalNAc polypeptide N-acetylgalactosaminyltransferases (GalNAc-Ts) catalyze mucin-type O-glycosylation by transferring α-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to Ser...

Forensic Psychiatry

20 March 2024

Joubert syndrome-derived induced pluripotent stem cells show altered neuronal differentiation in vitro

Cell Tissue Res. 2024 Mar 19. doi: 10.1007/s00441-024-03876-9. Online ahead of print.ABSTRACTJoubert syndrome (JS) is a recessively inherited congenital ataxia characterized by hypotonia, psychomotor delay,...

Anxiety

20 March 2024

Use of a Combination Lavender/Peppermint Aromatherapy Patch During Port Catheter Placement Under Monitored Anesthesia Care Does Not Reduce Time to Discharge Readiness: A Randomized Controlled Trial

J Integr Complement Med. 2024 Mar 19. doi: 10.1089/jicm.2023.0416. Online ahead of print.ABSTRACTBackground: Intraoperative anxiety is a common problem when Monitored Anesthesia Care (MAC) is...

Anxiety

20 March 2024

Electrophysiological Phenotypes of Hippocampal Synaptic and Network Functions in Cannabinoid Receptor 2 Knockout Mice

Cannabis Cannabinoid Res. 2024 Jan 22. doi: 10.1089/can.2023.0186. Online ahead of print.ABSTRACTBackground: The cannabinoid receptor 2 (CB2R), a cannabinoid receptor primarily expressed in immune cells,...

Psychopathy

20 March 2024

Therapeutic and risk relevance of psychopathy and general criminal attitude change in an institutional sexual offense treatment program

Behav Sci Law. 2024 Mar 19. doi: 10.1002/bsl.2654. Online ahead of print.ABSTRACTWe examined the interrelationships between psychopathy, changes in general criminal attitudes, and community recidivism...

Psychiatry

20 March 2024

Withdrawal catastrophizing scale: initial psychometric properties and implications for the study of opioid use disorder and hyperkatifeia

Am J Drug Alcohol Abuse. 2024 Mar 19:1-13. doi: 10.1080/00952990.2023.2298257. Online ahead of print.ABSTRACTBackground: Discovery of modifiable factors influencing subjective withdrawal experience might advance opioid...

Psychiatry

20 March 2024

Successful Clozapine Rechallenge After Clozapine-Induced Severe Anemia: A Case Report

Schizophr Bull. 2024 Mar 19:sbae028. doi: 10.1093/schbul/sbae028. Online ahead of print.ABSTRACTINTRODUCTION: Clozapine, a second-generation antipsychotic (SGA), is considered the gold standard medication to treat patients...

Psychiatry

20 March 2024

Ultrasensitive Nanofiber Biosensor: Rapid In Situ Chromatic Detection of Bacteria for Healthcare Innovation

ACS Appl Bio Mater. 2024 Mar 19. doi: 10.1021/acsabm.4c00038. Online ahead of print.ABSTRACTRapid detection of bacterial presence in skin wounds is crucial to prevent the...

Psychiatry

20 March 2024

Social support in older adults: Validation and norm values of a brief form of the Perceived Social Support Questionnaire (F-SozU K-6)

PLoS One. 2024 Mar 19;19(3):e0299467. doi: 10.1371/journal.pone.0299467. eCollection 2024.ABSTRACTBACKGROUND: Social relations are crucial for maintaining physical and mental health across the life span. As social...

Medicine

20 March 2024

Clinical effect analysis of different treatment schemes for children with ulnar and radial double fractures

Cir Cir. 2024 Mar 19. doi: 10.24875/CIRU.23000426. Online ahead of print.ABSTRACTOBJECTIVE: The objective of the study is to evaluate the safety and efficacy of three...

Medicine

20 March 2024

Antibacterial, Fatigue-Resistant, and Self-Healing Dressing from Natural-Based Composite Hydrogels for Infected Wound Healing

Biomacromolecules. 2024 Mar 19. doi: 10.1021/acs.biomac.3c01385. Online ahead of print.ABSTRACTThe treatment of infected wounds faces substantial challenges due to the high incidence and serious infection-related...

Medicine

20 March 2024

Emerging Role of Plasma Microbial Cell-free DNA in the Diagnosis of Pediatric Mucormycosis

Pediatr Infect Dis J. 2024 Mar 18. doi: 10.1097/INF.0000000000004331. Online ahead of print.ABSTRACTMucormycosis is a rare and devastating angioinvasive infection that can be challenging to...

Medicine

20 March 2024

Human Adenovirus B3 Associated Colitis and Hemophagocytic Lymphohistiocytosis in 9-year-old Previously Healthy Girl

Pediatr Infect Dis J. 2024 Mar 19. doi: 10.1097/INF.0000000000004328. Online ahead of print.NO ABSTRACTPMID:38502897 | DOI:10.1097/INF.0000000000004328

Medicine

20 March 2024

A Phase 3, Single-Arm Trial to Evaluate the Safety and Immunogenicity of a 20-Valent Pneumococcal Conjugate Vaccine in Healthy Children 15 Months Through <18 Years of Age

Pediatr Infect Dis J. 2024 Mar 15. doi: 10.1097/INF.0000000000004318. Online ahead of print.ABSTRACTBACKGROUND: A 20-valent pneumococcal conjugate vaccine (PCV20), containing 13-valent PCV (PCV13) components and...

Medicine

20 March 2024

Pediatric Otitis Media in the New Pneumococcal Conjugate Vaccines Era: What’s Next?

Pediatr Infect Dis J. 2024 Mar 15. doi: 10.1097/INF.0000000000004323. Online ahead of print.NO ABSTRACTPMID:38502893 | DOI:10.1097/INF.0000000000004323

Medicine

20 March 2024

Mucocutaneous Candidiasis: Insights Into the Diagnosis and Treatment

Pediatr Infect Dis J. 2024 Mar 13. doi: 10.1097/INF.0000000000004321. Online ahead of print.ABSTRACTRecent progress in the methods of genetic diagnosis of inborn errors of immunity...

Medicine

20 March 2024

Successful Treatment of a Fulminant Rothia mucilaginosa Central Nervous System Infection in an Adolescent With T-Cell Acute Lymphoblastic Leukemia

Pediatr Infect Dis J. 2024 Mar 13. doi: 10.1097/INF.0000000000004322. Online ahead of print.NO ABSTRACTPMID:38502880 | DOI:10.1097/INF.0000000000004322

Medicine

20 March 2024

Prevalence of Distal Symmetrical Polyneuropathy by Diabetes Prevention Program Treatment Group, Diabetes Status, Duration of Diabetes, and Cumulative Glycemic Exposure

Diabetes Care. 2024 Mar 19:dc232009. doi: 10.2337/dc23-2009. Online ahead of print.ABSTRACTOBJECTIVE: To assess associations between distal symmetric polyneuropathy (DSPN) and Diabetes Prevention Program (DPP) treatment...

Medicine

20 March 2024

Retroperitoneoscopic Simple Nondismembered Pyeloplasty with Da Vinci Si Assistance to Prevent Alignment Shift

J Laparoendosc Adv Surg Tech A. 2024 Mar 19. doi: 10.1089/lap.2023.0236. Online ahead of print.ABSTRACTAims: Retroperitoneoscopic simple nondismembered pyeloplasty (SNDP) with da Vinci Si assistance...

Neuroscience

20 March 2024

Stroke Thrombolysis: Can You Feel the Need for Speed?

Neurology. 2024 Apr 9;102(7):e209253. doi: 10.1212/WNL.0000000000209253. Epub 2024 Mar 19.NO ABSTRACTPMID:38502898 | DOI:10.1212/WNL.0000000000209253

Neuroscience

20 March 2024

Association of Time to Thrombolysis With Early Reperfusion After Alteplase and Tenecteplase in Patients With Large Vessel Occlusion

Neurology. 2024 Apr 9;102(7):e209166. doi: 10.1212/WNL.0000000000209166. Epub 2024 Mar 19.ABSTRACTBACKGROUND AND OBJECTIVES: Early treatment with intravenous alteplase increases the probability of lytic-induced reperfusion in large...

Neuroscience

20 March 2024

Longitudinal Change in Serum Neurofilament Light Chain in Type 2 Diabetes and Early Diabetic Polyneuropathy: ADDITION-Denmark

Diabetes Care. 2024 Mar 19:dc232208. doi: 10.2337/dc23-2208. Online ahead of print.ABSTRACTOBJECTIVE: To investigate the longitudinal development of neurofilament light chain (NfL) levels in type 2...

Neuroscience

20 March 2024

CXCL17 is an allosteric inhibitor of CXCR4 through a mechanism of action involving glycosaminoglycans

Sci Signal. 2024 Mar 19;17(828):eabl3758. doi: 10.1126/scisignal.abl3758. Epub 2024 Mar 19.ABSTRACTCXCL17 is a chemokine principally expressed by mucosal tissues, where it facilitates chemotaxis of monocytes,...

Gun Violence

20 March 2024

AOA Critical Issues Symposium: Gun Violence as a Public Health Crisis

J Bone Joint Surg Am. 2024 Mar 19. doi: 10.2106/JBJS.23.01260. Online ahead of print.ABSTRACTGun violence is an epidemic throughout the United States and is increasing...

Alcoholism

20 March 2024

Socioeconomic position indicators and risk of alcohol-related medical conditions: A national cohort study from Sweden

PLoS Med. 2024 Mar 19;21(3):e1004359. doi: 10.1371/journal.pmed.1004359. eCollection 2024 Mar.ABSTRACTBACKGROUND: Alcohol consumption contributes to excess morbidity and mortality in part through the development of alcohol-related...

Alcoholism

20 March 2024

Cerebellum and Aging: Update and Challenges

Aging Dis. 2024 Mar 1. doi: 10.14336/AD.2024.0220. Online ahead of print.ABSTRACTThe cerebellum plays a vital role in the aging process. With the aging of the...

Alcoholism

20 March 2024

Association of Histopathological and Biochemical Aspects of NAFLD With the Severity of Liver Fibrosis in Individuals With Obesity: Cross-sectional Study

Obes Surg. 2024 Mar 19. doi: 10.1007/s11695-024-07180-x. Online ahead of print.ABSTRACTBACKGROUND: Given the importance of fibrosis in the progression of non-alcoholic fatty liver disease (NAFLD),...

Alcoholism

20 March 2024

Non-Alcoholic Fatty Liver Disease May Be a Risk Factor for Liver Metastasis After Radical Surgery for Colorectal Cancer: A Retrospective Study

J Gastrointest Cancer. 2024 Mar 19. doi: 10.1007/s12029-024-01042-6. Online ahead of print.ABSTRACTPURPOSE: Distant metastasis develops in approximately one-third of patients with colorectal cancer (CRC) who...

Alcoholism

20 March 2024

Binge drinking in early adolescence : Results of the “Präventionsradar” from 2016 to 2023

Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz. 2024 Mar 19. doi: 10.1007/s00103-024-03861-1. Online ahead of print.ABSTRACTINTRODUCTION: In Germany, no other psychotropic substance is consumed as often and in such...

Alcoholism

20 March 2024

IL-8+ neutrophils drive inexorable inflammation in severe alcohol-associated hepatitis

J Clin Invest. 2024 Mar 19:e178616. doi: 10.1172/JCI178616. Online ahead of print.NO ABSTRACTPMID:38502218 | DOI:10.1172/JCI178616

Autism

20 March 2024

Letter to the Editor: Supporting Drivers with Autism and Police Officer Interactions-Connecticut’s Blue Envelope Program

J Autism Dev Disord. 2024 Mar 19. doi: 10.1007/s10803-024-06315-4. Online ahead of print.ABSTRACTThe rising prevalence of autism spectrum disorder (ASD) has led to increased efforts...

Autism

20 March 2024

Theory of Mind and Social Informant Discrepancy in Autism

Child Psychiatry Hum Dev. 2024 Mar 19. doi: 10.1007/s10578-024-01676-4. Online ahead of print.ABSTRACTWhen autistic youth are asked to assess their own social skills, they frequently...