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Age-Stratified Patterns of Suicide Methods in Bipolar Disorder: A Nationwide Cohort Study

AI Summary
  • People with bipolar disorder who die by suicide display distinct, age-dependent method patterns compared with the general population.
  • Higher adjusted odds of drowning (aOR 1.70, 95% CI 1.44 to 2.00) and jumping from a high place (aOR 1.31) in bipolar decedents.
  • Lower adjusted odds for charcoal burning and other gas poisoning (aOR 0.69) and for hanging (aOR 0.87); charcoal burning concentrated in younger and middle-aged decedents.
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Acta Psychiatr Scand. 2026 Aug 5. doi: 10.1111/acps.70132. Online ahead of print.

ABSTRACT

OBJECTIVES: Age-stratified suicide methods in bipolar disorder remain underexplored. This study compared method selection between suicide decedents with bipolar disorder and the general population.

METHODS: We identified 47,488 individuals with bipolar disorder between 2003 and 2023 from Taiwan’s nationwide health database and linked mortality records to ascertain suicide deaths. Using a decedent-only design, we compared the distribution of suicide methods between suicide decedents with bipolar disorder and those from the general population. Age-stratified (< 30, 30-49, 50-64, and ≥ 65 years) multivariable logistic regression analyses were performed with adjustment for sex, age at death, urbanization level, and employment status.

RESULTS: Among 1452 suicide deaths over 478,729 person-years (incidence: 303.3 per 100,000), the most common methods were hanging (28.0%), charcoal burning and other gas poisoning (20.9%), jumping from a high place (18.0%), drug overdose (16.9%), and drowning (11.4%). Suicide decedents in the bipolar cohort had higher odds of drowning (adjusted odds ratio [aOR]: 1.70, 95% confidence interval [CI]: 1.44-2.00) and jumping from a high place (aOR: 1.31, 95% CI: 1.14-1.50) but lower odds of charcoal burning and other gas poisoning (aOR: 0.69, 95% CI: 0.60-0.79) and hanging (aOR: 0.87, 95% CI: 0.77-0.98) than did general-population decedents (n = 81,159). Age-stratified analyses showed charcoal burning concentrated in younger and middle-aged decedents, drowning consistently elevated across age strata, and jumping elevated in middle-aged and older decedents.

CONCLUSION: Individuals with bipolar disorder who die by suicide exhibit distinct, age-dependent patterns of suicide methods. Therefore, prevention strategies should be tailored to both age groups and methods.

PMID:42555151 | DOI:10.1111/acps.70132

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