Baseline Mental Health Status and Early Psychiatric Outcomes after Metabolic-Bariatric Surgery: A Retrospective Cohort Study

30/08/2026

AI Summary

Preoperative mental health conditions linked to higher odds of early postoperative suicidal ideation (OR 6.75; p = 0.042).
Self-harm events were more frequent in MH patients; association directionally similar but not statistically significant (OR 5.10; p = 0.086).
Metabolic and weight-loss outcomes comparable between groups; causality cannot be inferred, and structured postoperative MH follow-up is advised.

AI Summary

OBJECTIVE: To evaluate whether documented preoperative mental health (MH) conditions were associated with early postoperative psychiatric events and metabolic outcomes after primary metabolic-bariatric surgery (MBS).

During 2-year follow-up, suicidal ideation was recorded in 6/217 (2.8%) in the MH group versus 1/265 (0.4%) in the non-MH group and self-harm (including suicide attempt) in 5/217 (2.3%) versus 1/265 (0.4%), respectively.

Basic summary

Obes Surg. 2026 Aug 29. doi: 10.1007/s11695-026-08918-5. Online ahead of print.

ABSTRACT

METHODS: A retrospective cohort study of adults who underwent primary MBS at a tertiary UK bariatric centre between April 2021 and March 2024 was conducted. Preoperative MH conditions and postoperative outcomes were identified via review of electronic health records. Comparisons between groups were analysed using Fisher’s exact test and regression models adjusted for age, sex, preoperative BMI, and surgery type.

RESULTS: Among 482 patients, 217 (45.0%) had at least one documented preoperative MH condition. During 2-year follow-up, suicidal ideation was recorded in 6/217 (2.8%) in the MH group versus 1/265 (0.4%) in the non-MH group and self-harm (including suicide attempt) in 5/217 (2.3%) versus 1/265 (0.4%), respectively. Preoperative MH conditions were associated with higher odds of postoperative suicidal ideation (OR 6.75, 95% CI 1.09-41.86; p = 0.0420), while the association with self-harm was directionally similar but not statistically significant (OR 5.10, 95% CI 0.80-32.72; p = 0.0860). Weight-loss and metabolic outcomes did not differ materially by baseline MH status.

CONCLUSIONS: In this single-centre cohort, patients with documented preoperative MH conditions achieved comparable metabolic benefit after surgery but had higher recorded early suicidality-related events. Although causality cannot be inferred, these findings support structured postoperative MH follow-up.

PMID:42667565 | DOI:10.1007/s11695-026-08918-5

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