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Beyond Binary-The Case for Amyloid Centiloid Quantification

AI Summary
  • Amyloid Centiloid quantification provides a continuous, standardised scale improving accuracy and comparability across PET tracers and centres.
  • Continuous Centiloid values detect early pathological change and sensitively track longitudinal and treatment related amyloid dynamics.
  • Adopting Centiloids supports harmonised thresholds for clinical decision making, research comparability and regulatory endpoints.
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JAMA. 2026 Jun 17. doi: 10.1001/jama.2026.10733. Online ahead of print.

NO ABSTRACT

PMID:42307963 | DOI:10.1001/jama.2026.10733

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