AI Summary
- Documented childhood maltreatment is associated with accelerated epigenetic ageing in adulthood, reflecting increased biological age relative to chronological age.
- Associations persisted after adjusting for sociodemographic, health behaviours, and mental health, suggesting independent effects of early adversity on biological ageing.
- Findings highlight epigenetic clocks as potential biomarkers for risk stratification and intervention targeting to mitigate long term health consequences.
JAMA Netw Open. 2026 Aug 3;9(8):e2628033. doi: 10.1001/jamanetworkopen.2026.28033.
NO ABSTRACT
PMID:42574017 | DOI:10.1001/jamanetworkopen.2026.28033
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