AI Summary
- Rising kratom use in the United States means physicians will increasingly encounter patients using unregulated, unstudied products.
- Safety remains uncertain due to lack of regulation, limited evidence, and potential harms from contamination, opioid effects, and withdrawal.
- Physicians should assess kratom use, manage withdrawal and toxicity, and counsel patients about unknown risks and treatment options.
Cleve Clin J Med. 2026 Aug 3;93(8):487-492. doi: 10.3949/ccjm.93a.25088.
ABSTRACT
As kratom products become more widely used in the United States, physicians will be more likely to encounter patients who are using these unregulated and unstudied substances. This focused review addresses questions such as what kratom is, whether it is safe, who is using it (and why), how to treat patients who are using it, and what to tell them.
PMID:42547284 | DOI:10.3949/ccjm.93a.25088
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