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Severe Cholinesterase Reduction Associated With Rivastigmine Patch: Two Case Reports

AI Summary
  • Two case reports describe severe cholinesterase reduction temporally associated with rivastigmine transdermal patch use.
  • Marked enzyme decline produced clinically significant cholinergic effects necessitating dose reduction or discontinuation.
  • Advocate cholinesterase monitoring, vigilance for interactions and caution in hepatic impairment or frail patients when prescribing rivastigmine patches.
Summarise with AI (MRCPsych/FRANZCP)

Am J Ther. 2026 Oct 28. doi: 10.1097/MJT.0000000000002254. Online ahead of print.

NO ABSTRACT

PMID:42950131 | DOI:10.1097/MJT.0000000000002254

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