AI Summary
- Genetic polymorphisms significantly modulate salivary cortisol variability and can confound associations with psychiatric outcomes.
- Incorporate genotyping of candidate loci and polygenic scores to improve reproducibility and mechanistic interpretation of cortisol psychiatry studies.
- Future studies should adopt standardised sampling, larger cohorts, report genetic covariates, and address ethical and logistical implications of genotyping.
Psychoneuroendocrinology. 2026 Oct 5:108026. doi: 10.1016/j.psyneuen.2026.108026. Online ahead of print.
NO ABSTRACT
PMID:42830247 | DOI:10.1016/j.psyneuen.2026.108026
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