- In 334 people with MS, 14.7% declined neurocognitive testing.
- Progressive MS and anxiety-related disorders independently predicted higher odds of declining neurocognitive testing (ORs 2.1 and 2.5).
- Absence of self-reported cognitive concerns associated with lower odds of declining testing (OR 0.3, 95% CI 0.2 to 0.7, p=0.004).
Mult Scler. 2026 Oct 17:13524585261491122. doi: 10.1177/13524585261491122. Online ahead of print.
ABSTRACT
In 334 people with multiple sclerosis, a backward stepwise regression analysis was conducted to identify clinical characteristics that predict who declines neurocognitive testing (p < 0.05), from demographics, disease-related variables, psychiatric diagnoses, and self-reported cognitive concerns. The mean age was 44.1 years (standard deviation = 11.4), the median Expanded Disability Status Scale was 2.5 (1.5-4.0), 79.8% had relapsing-remitting MS, and 14.7% declined testing. Independent correlates of declining neurocognitive testing included progressive MS (odds ratio = 2.1, 95% confidence interval = [1.0, 4.4], p = 0.046), anxiety-related disorders (odds ratio = 2.5, 95% confidence interval = [1.3, 4.9], p = 0.007), and the absence of self-reported cognitive concerns (odds ratio = 0.3, 95% confidence interval = [0.2, 0.7], p = 0.004). People with multiple sclerosis with these clinical characteristics are more likely to decline neurocognitive testing.
PMID:42891507 | DOI:10.1177/13524585261491122
Share Evidence Blueprint
Save to Google Notes
Search Google Scholar
Save as PDF
⭐ My Revision List
