Category: Schizophrenia

How concerns about the naming and the diagnostic concept of “schizophrenia” subtly reinforce each other, and what could be done in this respect

World Psychiatry. 2026 Oct;25(3):345-346. doi: 10.1002/wps.70116.NO ABSTRACTPMID:42742607 | DOI:10.1002/wps.70116

RAISR4D Schizophrenia

Advancing mental health for all as a response to global change: WPA achievements under the Action Plan 2023-2026

World Psychiatry. 2026 Oct;25(3):493-494. doi: 10.1002/wps.70110.NO ABSTRACTPMID:42742603 | DOI:10.1002/wps.70110

RAISR4D Schizophrenia

Consensus-based clinical and research recommendations for use of glucagon-like peptide-1 receptor agonists in the context of eating disorders: a modified Delphi study

World Psychiatry. 2026 Oct;25(3):465-474. doi: 10.1002/wps.70096.ABSTRACTGlucagon-like peptide-1 receptor agonists (GLP-1RAs), initially developed for type 2 diabetes management and later expanded to obesity treatment, have shown...

RAISR4D Schizophrenia

Network analysis of the genetic relationships between twenty psychiatric and substance use disorders

World Psychiatry. 2026 Oct;25(3):444-453. doi: 10.1002/wps.70094.ABSTRACTWe sought to clarify, using network analysis, the structure of genetic risk factors for a wide range of psychiatric and...

RAISR4D Schizophrenia

Metformin, but Not Aripiprazole, Was Associated With Attenuation of Weight Gain in Clozapine-Treated Inpatients With Concurrent Disorders: A Repeated Measures Cohort Analysis: La metformine, mais non l’aripiprazole, a été associée à une atténuation du gain de poids chez les patients hospitalisés traités par la clozapine et présentant des troubles concomitants : une analyse de cohorte à mesures répétées

Can J Psychiatry. 2026 Sep 15:7067437261486956. doi: 10.1177/07067437261486956. Online ahead of print.ABSTRACTBackgroundIndividuals with schizophrenia and concurrent substance use disorders (SUDs) face a high risk of...

RAISR4D Schizophrenia

Reconstructing Identity After Psychiatric Rehabilitation: A Phenomenological Study of Psychosocial Recovery Among Individuals with Schizophrenia in Indonesia

Issues Ment Health Nurs. 2026 Sep 15:1-11. doi: 10.1080/01612840.2026.2720520. Online ahead of print.ABSTRACTPsychiatric rehabilitation supports recovery and community reintegration among individuals with schizophrenia, but persistent...

RAISR4D Schizophrenia

Cobenfy (xanomeline-trospium chloride) for schizophrenia: A clinical update

Australas Psychiatry. 2026 Sep 15:10398562261486319. doi: 10.1177/10398562261486319. Online ahead of print.ABSTRACTObjectiveTo provide Australian doctors working in psychiatry with a clinical update on xanomeline-trospium chloride (Cobenfy),...

RAISR4D Schizophrenia

Disruption of prefrontal and superior temporal gyrus white matter networks in antipsychotic-treated schizophrenia with comorbid metabolic syndrome

Front Psychiatry. 2026 Aug 28;17:1878935. doi: 10.3389/fpsyt.2026.1878935. eCollection 2026.ABSTRACTBACKGROUND: Metabolic syndrome (MS) is a frequent comorbidity in schizophrenia, yet the characteristics of white matter (WM)...

RAISR4D Schizophrenia

14/09/2026

Mapping Psychosocial Disability in Schizophrenia: Network Analysis of a Relatives-Rated Clinical Scale – CORRIGENDUM

Eur Psychiatry. 2026 Sep 14;69(1):e92. doi: 10.1192/j.eurpsy.2026.12256.NO ABSTRACTPMID:42734145 | DOI:10.1192/j.eurpsy.2026.12256

RAISR4D Schizophrenia

14/09/2026

Beyond stigma: reframing antipsychotics as medical treatment

Br J Psychiatry. 2026 Sep 14:1-3. doi: 10.1192/bjp.2026.10786. Online ahead of print.ABSTRACTAntipsychotic non-adherence, driven partly by stigma, worsens outcomes in severe mental illness. Beyond ameliorating...

RAISR4D Schizophrenia

14/09/2026

Dopamine antagonists and dynamic symptom networks in schizophrenia

Br J Psychiatry. 2026 Sep 14:1-7. doi: 10.1192/bjp.2026.10775. Online ahead of print.ABSTRACTBACKGROUND: The symptoms of psychotic disorders do not exist in isolation, but interact with...

RAISR4D Schizophrenia

13/09/2026

Common genetic variants are associated with increased likelihood of latent co-occurring neurodevelopmental and mental health factors among autistic individuals

Mol Psychiatry. 2026 Sep 12. doi: 10.1038/s41380-026-03880-1. Online ahead of print.ABSTRACTAutistic individuals show elevated rates of co-occurring neurodevelopmental and mental health conditions, yet the genetic...

RAISR4D Schizophrenia

Pseudocyesis in a 37-year-old male with schizophrenia: A rare case report

Ind Psychiatry J. 2026 May-Aug;35(2):233-234. doi: 10.4103/ipj.ipj_443_25. Epub 2026 Aug 20.NO ABSTRACTPMID:42724863 | PMC:PMC13561469 | DOI:10.4103/ipj.ipj_443_25

RAISR4D Schizophrenia

Impact of schizophrenia on coronary artery bypass grafting outcomes: a nationwide analysis

Ann Med Surg (Lond). 2026 Jul 30;88(9):5821-5827. doi: 10.1097/MS9.0000000000005349. eCollection 2026 Sep.ABSTRACTBACKGROUND: Schizophrenia is associated with an elevated cardiovascular disease burden and mortality. However, outcomes...

RAISR4D Schizophrenia

The association of ADHD and ADHD medication with adherence to pharmacotherapy for type 2 diabetes: a population-based cohort study from seven countries

EClinicalMedicine. 2026 Aug 31;99:104182. doi: 10.1016/j.eclinm.2026.104182. eCollection 2026 Sep.ABSTRACTBACKGROUND: Attention-deficit/hyperactivity disorder (ADHD) may compromise adherence to pharmacotherapy in adults with type 2 diabetes, but the...

RAISR4D Schizophrenia

Sex-related differences in the cortico-thalamo-cerebellar circuit in patients with schizophrenia

Front Psychiatry. 2026 Aug 27;17:1921553. doi: 10.3389/fpsyt.2026.1921553. eCollection 2026.ABSTRACTBACKGROUND: Schizophrenia is characterized by substantial clinical heterogeneity, with average differences between males and females in symptom...

RAISR4D Schizophrenia

Prevalence and correlates of criminal victimization in Taiwanese outpatients with severe mental illness: a cross-sectional study

Front Psychiatry. 2026 Aug 27;17:1921017. doi: 10.3389/fpsyt.2026.1921017. eCollection 2026.ABSTRACTBACKGROUND: Individuals with severe mental illness (SMI), including schizophrenia and bipolar disorder, are at increased risk of...

RAISR4D Schizophrenia

Turkish adaptation study of the Metacognition Assessment Scale-Abbreviated in psychotic disorders

Front Psychol. 2026 Aug 27;17:1884522. doi: 10.3389/fpsyg.2026.1884522. eCollection 2026.ABSTRACTBACKGROUND: Metacognition refers to the ability to recognize one's own and others' feelings and thoughts and to...

RAISR4D Schizophrenia

Severe recurrent hypernatremia and probable lithium-associated nephrogenic diabetes insipidus following pancreatectomy in a patient with schizophrenia: a case report

Front Med (Lausanne). 2026 Aug 27;13:1925920. doi: 10.3389/fmed.2026.1925920. eCollection 2026.ABSTRACTBACKGROUND: Nephrogenic diabetes insipidus (NDI) is characterized by impaired renal responsiveness to arginine vasopressin, causing defective...

RAISR4D Schizophrenia

Association of Concomitant Amlodipine Use With Serum Olanzapine Concentrations and Clinical Outcomes in Patients With Schizophrenia

Hum Psychopharmacol. 2026 Sep;41(5):e70062. doi: 10.1002/hup.70062.ABSTRACTOBJECTIVE: To examine whether concomitant amlodipine use was associated with steady-state serum olanzapine concentration and clinical outcomes in patients with...

RAISR4D Schizophrenia

Internal Experiences of Self-Stigma Among Patients with Schizophrenia Based on the Common-Sense Model: A Qualitative Study

Issues Ment Health Nurs. 2026 Sep 10:1-9. doi: 10.1080/01612840.2026.2704666. Online ahead of print.ABSTRACTPatients with schizophrenia endure not only severe symptom burden but also prolonged exposure...

RAISR4D Schizophrenia

In Vivo Rodent Studies with the Novel PET Tracer [18F]PGM028299: An Inhibitor of D-Amino Acid Oxidase

J Med Chem. 2026 Sep 10;69(17):20761-20771. doi: 10.1021/acs.jmedchem.6c01035.ABSTRACTAbnormal N-methyl-d-aspartate receptor (NMDAr) function is implicated in schizophrenia and other neuropsychiatric disorders. Enhancing NMDAr signaling can be...

RAISR4D Schizophrenia

Diminished general and sexual hedonic capacity in schizophrenia – a clinical and neural characterization

Front Psychiatry. 2026 Aug 14;17:1824523. doi: 10.3389/fpsyt.2026.1824523. eCollection 2026.ABSTRACTBACKGROUND: Individuals with Schizophrenia are often reported to suffer from sexual dysfunction, but despite its clinical and...

RAISR4D Schizophrenia

Advanced biomaterials and digital twins for precision psychiatry: neuroimmune modulation and AI-guided therapeutics

Front Bioeng Biotechnol. 2026 Aug 26;14:1917260. doi: 10.3389/fbioe.2026.1917260. eCollection 2026.ABSTRACTPrecision psychiatry should be reframed as an integrated bioengineering problem-not simply as a computational challenge of...

RAISR4D Schizophrenia

Low willingness and patient-caregiver concordance regarding long-acting injectable antipsychotics in schizophrenia cases: a convergent mixed-methods study

Front Psychiatry. 2026 Aug 26;17:1931871. doi: 10.3389/fpsyt.2026.1931871. eCollection 2026.ABSTRACTINTRODUCTION: Long-acting injectable antipsychotics (LAIAs) may improve treatment continuity in schizophrenia, yet their acceptance in community-based care...

RAISR4D Schizophrenia

Risk factors of aggressive behavior in female patients with schizophrenia

Front Psychiatry. 2026 Aug 26;17:1839475. doi: 10.3389/fpsyt.2026.1839475. eCollection 2026.ABSTRACTOBJECTIVE: To investigate the risk factors associated with violent behavior in female patients with schizophrenia.METHODS: A total...

RAISR4D Schizophrenia

Agitation/excitement in male patients with treatment-resistant schizophrenia is associated with lower total cholesterol levels

Front Psychiatry. 2026 Aug 26;17:1917517. doi: 10.3389/fpsyt.2026.1917517. eCollection 2026.ABSTRACTBACKGROUND: Treatment-Resistant Schizophrenia (TRS) in males with agitation/excitement poses a clinical challenge. The pathophysiological mechanisms of agitation/excitement...

RAISR4D Schizophrenia

Commentary on the ANZJP Grading of Recommendations, Assessment, Development and Evaluations (GRADE) guidelines for the management of schizophrenia – Where are the recommendations for methamphetamine-related psychoses?

Aust N Z J Psychiatry. 2026 Sep 9:48674261475184. doi: 10.1177/00048674261475184. Online ahead of print.ABSTRACTThe ANZJP Grading of Recommendations, Assessment, Development and Evaluations (GRADE) guidelines for...

RAISR4D Schizophrenia

The integrated Lei-CNS PBPK-PD model effectively predicts clozapine brain disposition and D2 receptor occupancy in humans

Br J Clin Pharmacol. 2026 Sep 9. doi: 10.1002/bcp.70788. Online ahead of print.ABSTRACTAIM: Clozapine, used for treatment-resistant schizophrenia, has a narrow therapeutic window and highly...

RAISR4D Schizophrenia

Association between body mass index and serum concentrations of olanzapine and selective serotonin reuptake inhibitors in patients with eating disorders

Eur J Clin Pharmacol. 2026 Sep 10;82(9):249. doi: 10.1007/s00228-026-04175-8.ABSTRACTPURPOSE: Selective serotonin reuptake inhibitors (SSRIs) and olanzapine are frequently prescribed for patients with anorexia nervosa and...

RAISR4D Schizophrenia

What systems must protect: relational care, uncertainty and recovery in early psychosis care

BMJ Ment Health. 2026 Sep 9;29(1):e302981. doi: 10.1136/bmjment-2026-302981.ABSTRACTEarly psychosis services, including early intervention in psychosis programmes (EIP), are built on principles of timely access, continuity...

RAISR4D Schizophrenia

A Summary for Non-Psychiatrists of the Australian and New Zealand Journal of Psychiatry Grading of Recommendations, Assessment, Development and Evaluations (GRADE) Guidelines for the Management of Schizophrenia

Med J Aust. 2026 Sep;224(9):e70287. doi: 10.5694/mja2.70287.ABSTRACTINTRODUCTION: This article summarises the recently published 'Australian and New Zealand Journal of Psychiatry (ANZJP) Grading of Recommendations, Assessment,...

RAISR4D Schizophrenia

Bringing telepsychiatry to rural primary care: a 12-month observational evaluation in severe mental illness

Fam Pract. 2026 Jul 31;43(5):cmag076. doi: 10.1093/fampra/cmag076.ABSTRACTBACKGROUND: Specialist psychiatric access and continuity remain difficult in rural communities, particularly for adults with severe mental illness.OBJECTIVES: To...

RAISR4D Schizophrenia

Stakeholder perspectives on artificial intelligence in schizophrenia care

Psychol Med. 2026 Sep 9;56:e265. doi: 10.1017/S0033291726105728.ABSTRACTBACKGROUND: Artificial intelligence (AI) is explored as a tool to expand access to mental health care, offering support and...

RAISR4D Schizophrenia

Management of Schizophrenia With Clozapine in the Context of Comorbid Waldenstrom’s Macroglobulinemia

J Clin Psychopharmacol. 2026 Sep 9. doi: 10.1097/JCP.0000000000002256. Online ahead of print.NO ABSTRACTPMID:42713779 | DOI:10.1097/JCP.0000000000002256

RAISR4D Schizophrenia

Association of betel quid chewing with specific major psychiatric disorders in Taiwan Biobank-NHIRD linked data

Epidemiol Psychiatr Sci. 2026 Sep 9;35:e54. doi: 10.1017/S2045796026100936.ABSTRACTAIMS: Betel quid chewing (BQC) is a common psychoactive habit in Taiwan and other Asian regions. Evidence regarding...

RAISR4D Schizophrenia

Care facilitation by Accredited Social Health Activists (ASHAs) to improve outcomes of persons with psychiatric disorders: Results from a randomized controlled trial in South India

Indian J Psychiatry. 2026 Aug;68(Suppl 2):S383-S391. doi: 10.4103/indianjpsychiatry_1013_24. Epub 2026 Aug 17.ABSTRACTBACKGROUND: The role of Accredited Social Health Activists (ASHAs) in improving short-term outcomes-symptoms, burden,...

RAISR4D Schizophrenia

Prevalence of physical illnesses and lifestyle factors among severely mentally ill in a community

Indian J Psychiatry. 2026 Aug;68(Suppl 2):S457-S461. doi: 10.4103/indianjpsychiatry_1151_24. Epub 2026 Aug 17.ABSTRACTPhysical health issues are frequent and often inadequately addressed in individuals with severe mental...

RAISR4D Schizophrenia

Electroconvulsive Therapy Refusal in Severe Psychosis: Navigating Capacity, Surrogate Decision-Making, and Ethical Duty

Cureus. 2026 Aug 9;18(8):e114204. doi: 10.7759/cureus.114204. eCollection 2026 Aug.ABSTRACTElectroconvulsive therapy (ECT) remains among the most effective interventions in psychiatry for severe depression, catatonia, and treatment-resistant...

RAISR4D Schizophrenia

Neurophysiological subtyping of schizophrenia reveals a reproducible phenotype with temporoparietal circuit disruptions

Gen Psychiatr. 2026 Oct;39(5):e70047. doi: 10.1002/gps3.70047. Epub 2026 Sep 8.ABSTRACTBACKGROUND: Heterogeneity in schizophrenia (SCZ) remains a major obstacle to the development of effective treatment.AIMS: This...

RAISR4D Schizophrenia

Neural Cell Adhesion Molecule-1 Gene Polymorphism Increases the Risk of Cognitive Dysfunction in Schizophrenia Spectrum Disorder

Indian J Clin Biochem. 2026 Oct;41(5):792-798. doi: 10.1007/s12291-024-01290-0. Epub 2024 Dec 13.ABSTRACTNeural cell adhesion molecule-1 (NCAM-1), a marker of synaptic plasticity is reported to be...

RAISR4D Schizophrenia

Color Perception in Patients with Schizophreniza and Their Healthy First-degree Relatives: A Cross-sectional Study

Indian J Psychol Med. 2026 Sep 6:02537176261480351. doi: 10.1177/02537176261480351. Online ahead of print.ABSTRACTBACKGROUND: Endophenotypic markers are an important area of study for a better understanding...

RAISR4D Schizophrenia

The association between metabolic dysfunction-associated fatty liver disease and left ventricular mass index in patients with schizophrenia with long-term hospitalization

Front Endocrinol (Lausanne). 2026 Aug 25;17:1919402. doi: 10.3389/fendo.2026.1919402. eCollection 2026.ABSTRACTBACKGROUND: Patients with schizophrenia have a high cardiovascular risk, especially long-term hospitalized cases where physical issues...

RAISR4D Schizophrenia

Healthcare professionals’ views on implementing digital health tools in psychosis: a national survey in the UK

BMJ Digit Health Ai. 2025 Jun 11;1(1):e000005. doi: 10.1136/bmjdhai-2025-000005. eCollection 2025.ABSTRACTOBJECTIVE: Psychosis is a severe mental health problem and a huge public health challenge, but...

RAISR4D Schizophrenia

Next-generation wearable sensors for biopsychosocial care in mental health: a narrative review

BMJ Digit Health Ai. 2025 Jul 14;1(1):e000018. doi: 10.1136/bmjdhai-2025-000018. eCollection 2025.ABSTRACT12% of the global population experiences mental disorders, contributing to a growing public health crisis....

RAISR4D Schizophrenia

No evidence for a generalised predictive processing deficit in psychosis: A meta-analysis

Psychol Med. 2026 Sep 9;56:e268. doi: 10.1017/S0033291726105455.ABSTRACTBACKGROUND: The influential predictive processing theory of psychosis posits that symptoms arise from an imbalanced weighting of predictions (priors)...

RAISR4D Schizophrenia

Course of head growth from birth to adolescence across the psychosis spectrum

Psychol Med. 2026 Sep 9;56:e267. doi: 10.1017/S0033291726105418.ABSTRACTBACKGROUND: Charting developmental abnormalities in future psychotic disorder could help identify pathogenic processes. Head circumference (HC) is a proxy...

RAISR4D Schizophrenia

08/09/2026

Cognitive Impairment in Schizophrenia Across Different Clinical Manifestations and Its Association With Symptom Severity and Functional Status

Brain Behav. 2026 Sep;16(9):e71734. doi: 10.1002/brb3.71734.ABSTRACTOBJECTIVE: To explore the cognitive impairment in patients with schizophrenia of different clinical manifestations and its relationship with symptom severity...

RAISR4D Schizophrenia

08/09/2026

Circulating cell-free DNA and NETosis-related biomarkers in schizophrenia: association with clinical features and treatment

World J Biol Psychiatry. 2026 Sep 7:1-10. doi: 10.1080/15622975.2026.2729050. Online ahead of print.ABSTRACTOBJECTIVES: Schizophrenia is known to be accompanied by chronic sterile inflammation and elevated...

RAISR4D Schizophrenia

07/09/2026

Testing for Genetic Interactions in Complex Disease With Distance Correlation

Biom J. 2026 Oct;68(5):e70150. doi: 10.1002/bimj.70150.ABSTRACTUnderstanding epistasis (genetic interaction) may shed some light on the genomic basis of common diseases, including disorders of maximum interest...

RAISR4D Schizophrenia

07/09/2026

Whole-Exome and Whole-Genome Sequencing of Candidate Pharmacogenomic and Schizophrenia-Related Genes in Sudanese Families with Schizophrenia

Pharmgenomics Pers Med. 2026 Sep 2;19:616976. doi: 10.2147/PGPM.S616976. eCollection 2026.ABSTRACTBACKGROUND: Schizophrenia is considered a neuro-developmental disorder leading to disastrous lifelong disability of the patients and...

RAISR4D Schizophrenia

06/09/2026

Drug utilisation and adverse drug reaction monitoring in schizophrenic patients: A tertiary care hospital study in India

Bioinformation. 2026 Jun 30;22(6):3568-3571. doi: 10.6026/973206300223568. eCollection 2026.ABSTRACTInadequate and poorly documented data on psychotropic drug utilization in schizophrenia in India necessitates systematic evaluation of prescribing...

RAISR4D Schizophrenia

05/09/2026

Resting-state brain age is associated with cognitive and sensorimotor abnormalities in schizophrenia spectrum disorders: a validation & longitudinal study

Transl Psychiatry. 2026 Sep 4;16(1):451. doi: 10.1038/s41398-026-04426-3.ABSTRACTBrain-age models use neuroimaging features to predict chronological age. The resulting brain-age gap (BAG), defined as predicted brain age...

RAISR4D Schizophrenia

05/09/2026

Imaging Astrogliosis in Schizophrenia: Some Methodological Considerations

Biol Psychiatry Cogn Neurosci Neuroimaging. 2026 Sep;11(9):1048-1050. doi: 10.1016/j.bpsc.2026.06.008.NO ABSTRACTPMID:42697619 | DOI:10.1016/j.bpsc.2026.06.008

RAISR4D Schizophrenia

05/09/2026

Mental disorders, receipt of cardiac care following myocardial infarction and the impact of the COVID-19 pandemic: a cohort study

BMJ Open. 2026 Sep 4;16(9):e124463. doi: 10.1136/bmjopen-2026-124463.ABSTRACTOBJECTIVES: To compare receipt of guideline-informed myocardial infarction (MI) care by mental disorder and assess how the COVID-19 pandemic...

RAISR4D Schizophrenia

Glutamatergic Modulators in Schizophrenia: Are We Ready to Move Beyond the Narrow Focus on Dopamine? A Potential Paradigm Shift in Psychopharmacology

Alpha Psychiatry. 2026 Aug 5;27(4):52026. doi: 10.31083/AP52026. eCollection 2026 Aug.NO ABSTRACTPMID:42694905 | PMC:PMC13540019 | DOI:10.31083/AP52026

RAISR4D Schizophrenia

Disentangling Anhedonia and Self-Stigma in Schizophrenia Using Bayesian Network Analysis

Alpha Psychiatry. 2026 Jul 28;27(4):50731. doi: 10.31083/AP50731. eCollection 2026 Aug.ABSTRACTBACKGROUND: The interrelationships among the negative symptoms of schizophrenia and factors affecting quality of life remain...

RAISR4D Schizophrenia

Global Burden and Inequalities in Mental Disorders Across Countries and Territories: 1990 to 2021

Alpha Psychiatry. 2026 Aug 13;27(4):51756. doi: 10.31083/AP51756. eCollection 2026 Aug.ABSTRACTBACKGROUND: Although the global burden of mental disorders has been extensively documented, systematic assessments of cross-country...

RAISR4D Schizophrenia

Polysomnographic Parameters in Schizoaffective Disorder: A Systematic Review and Meta-Analysis

Alpha Psychiatry. 2026 Aug 19;27(4):52900. doi: 10.31083/AP52900. eCollection 2026 Aug.ABSTRACTBACKGROUND: Schizoaffective disorder (SZA) is a severe psychiatric condition characterized by overlapping affective and psychotic features;...

RAISR4D Schizophrenia

The Effect of Acute Psychotic Period on Physiological Values Measured in Blood in Male Patients With Schizophrenia

Alpha Psychiatry. 2026 Aug 21;27(4):53389. doi: 10.31083/AP53389. eCollection 2026 Aug.ABSTRACTBACKGROUND: There is increasing evidence that plasma osmolarity is an independent prognostic factor associated with mortality...

RAISR4D Schizophrenia

Supporting continuous glucose monitoring for people with serious mental illness and type 2 diabetes: a co-design study for a structured intervention

Front Health Serv. 2026 Aug 20;6:1807689. doi: 10.3389/frhs.2026.1807689. eCollection 2026.ABSTRACTINTRODUCTION: Individuals with serious mental illness (SMI), such as schizophrenia or bipolar disorder, are at a...

RAISR4D Schizophrenia

Associations among subjective cognitive complaints, perceived social support, and medication adherence in patients with psychotic disorders

Front Psychiatry. 2026 Aug 20;17:1762058. doi: 10.3389/fpsyt.2026.1762058. eCollection 2026.ABSTRACTBACKGROUND: Medication adherence is essential for the management of psychotic disorders, yet it remains difficult for many...

RAISR4D Schizophrenia

Nauclea officinalis extract rescues working memory deficits in adolescent maternal immune activation offspring by restoring cholinergic signaling

Front Cell Dev Biol. 2026 Aug 20;14:1918425. doi: 10.3389/fcell.2026.1918425. eCollection 2026.ABSTRACTOBJECTIVE: Maternal immune activation (MIA) is a key risk factor for schizophrenia-related cognitive deficits, linked...

RAISR4D Schizophrenia

The effect of communication skills-focused psychoeducation on subjective well-being of caregivers of individuals with schizophrenia: a three-arm randomized controlled trial

BMC Psychiatry. 2026 Jul 24;26(1):697. doi: 10.1186/s12888-026-08413-2.ABSTRACTBACKGROUND: Caregivers of individuals with schizophrenia face emotional and psychological challenges that affect their subjective well-being (SWB). Despite their...

RAISR4D Schizophrenia

03/09/2026

Functional psychosurgery in psychiatry: indications and preoperative evaluation. A narrative review

Front Psychiatry. 2026 Aug 19;17:1844401. doi: 10.3389/fpsyt.2026.1844401. eCollection 2026.ABSTRACTFunctional neurosurgery has evolved from a marginal and controversial intervention into a promising, technically feasible option for...

RAISR4D Schizophrenia

03/09/2026

Repetitive transcranial magnetic stimulation: advances for psychiatric disorders

Front Psychiatry. 2026 Aug 19;17:1832754. doi: 10.3389/fpsyt.2026.1832754. eCollection 2026.ABSTRACTRepetitive transcranial magnetic stimulation (rTMS) has accumulated substantial exploratory evidence in the treatment of major Depressive Disorders,...

RAISR4D Schizophrenia

Impact of atypical antipsychotics on cytokine profiles in schizophrenia: An 8-week longitudinal study

Indian J Pharmacol. 2026 Sep 1;58(5):558-566. doi: 10.4103/ijp.ijp_63_26. Epub 2026 Sep 2.ABSTRACTBACKGROUND: Schizophrenia has traditionally been conceptualized through dopaminergic and glutamatergic frameworks. In recent years,...

RAISR4D Schizophrenia

Evaluation of the Psychometric Scale Properties of Reflective Functioning Questionnaire (RFQ-8) in Persons with Schizophrenia Spectrum Disorders and Healthy Controls

J Pers Assess. 2026 Sep 2:1-10. doi: 10.1080/00223891.2026.2722651. Online ahead of print.ABSTRACTThere is a need to effectively measure mentalization in people with Schizophrenia Spectrum Disorders...

RAISR4D Schizophrenia

Association of Pre-ECT Anxiety Symptoms With Electroconvulsive Therapy Treatment Efficacy in Schizophrenia: A Retrospective Observational Cohort Study

J ECT. 2026 Sep 2. doi: 10.1097/YCT.0000000000001315. Online ahead of print.ABSTRACTOBJECTIVES: Pre-ECT anxiety symptoms are common among patients undergoing Electroconvulsive Therapy (ECT). In this retrospective...

RAISR4D Schizophrenia

Temporal Trends in Autologous Breast Reconstruction Among Patients With Psychiatric Diagnoses: From Disparity to Equity

Plast Reconstr Surg Glob Open. 2026 Sep 1;14(9):e8076. doi: 10.1097/GOX.0000000000008076. eCollection 2026 Sep.ABSTRACTBACKGROUND: During the last decades, advances in microsurgical techniques and equipment, alongside improvements...

RAISR4D Schizophrenia

Prevalence and Associated Factors of Metabolic Dysfunction-Associated Steatotic Liver Disease Across Obesity Metabolic Phenotypes in Chronic Schizophrenia

Int J Gen Med. 2026 Aug 28;19:620778. doi: 10.2147/IJGM.S620778. eCollection 2026.ABSTRACTBACKGROUND: Chronic schizophrenia patients often present with exacerbated clinical symptoms and higher rates of fatty...

RAISR4D Schizophrenia

Perceived temporal reorganization during psychiatric hospitalization among people with schizophrenia: a qualitative interview study

Front Psychiatry. 2026 Aug 18;17:1869125. doi: 10.3389/fpsyt.2026.1869125. eCollection 2026.ABSTRACTBACKGROUND: Schizophrenia involves not only disturbances in thought, perception, and self-experience, but also disruptions in subjective temporality....

RAISR4D Schizophrenia

NMDA receptor ablation in medial prefrontal cortex disrupts value updating and reward history integration

Neuropsychopharmacology. 2026 Sep 1. doi: 10.1038/s41386-026-02534-8. Online ahead of print.ABSTRACTSchizophrenia, a serious mental illness, is associated with evidence of NMDA receptor (NMDAR) dysfunction and characterized...

RAISR4D Schizophrenia

AKAP11 links autophagy to cognitive impairment in psychiatric diseases

Autophagy. 2026 Sep 1:1-3. doi: 10.1080/15548627.2026.2709295. Online ahead of print.ABSTRACTSchizophrenia (SCZ) and bipolar disorder (BD) share genetic risk factors and cognitive impairments, yet the underlying...

RAISR4D Schizophrenia

Integrating transposable elements into blood gene regulatory networks reveals connectivity loss for schizophrenia genes

J Clin Invest. 2026 Sep 1;136(17):e203491. doi: 10.1172/JCI203491. eCollection 2026 Sep 1.ABSTRACTIn patients with schizophrenia we found that genes and dark genome disconnect. This opens...

RAISR4D Schizophrenia

Learning the Affective Value of Others in Schizophrenia: Examining the Role of Negative Symptoms and Cognitive Deficits

J Psychopathol Behav Assess. 2020 Dec;42(4):714-724. doi: 10.1007/s10862-020-09818-3. Epub 2020 Jun 9.ABSTRACTPrior research has examined the hypothesis that negative symptoms, such as anhedonia and lack...

RAISR4D Schizophrenia

Study protocol for the Danish High Risk and Resilience Study VIA 19 – from age 15 to age 19: transition from adolescence to early adulthood

Front Psychiatry. 2026 Aug 17;17:1848366. doi: 10.3389/fpsyt.2026.1848366. eCollection 2026.ABSTRACTBACKGROUND: Longitudinal clinical cohorts following individuals, who are born to parents with severe mental illness, from childhood...

RAISR4D Schizophrenia

Synergising latent profile analysis and network analysis to elucidate the relationships among emotion dysregulation, post-traumatic stress disorder, dissociation, psychosis, and affective symptoms in individuals with trauma and severe mental illness

Int J Clin Health Psychol. 2026 Apr-Jun;26(2):100714. doi: 10.1016/j.ijchp.2026.100714. Epub 2026 Aug 25.ABSTRACTBACKGROUND: Trauma exposure and emotion dysregulation are transdiagnostic risk factors for post-traumatic stress...

RAISR4D Schizophrenia

Motor dysfunctions as an intermediate phenotype of schizophrenia: a systematic review

Zh Nevrol Psikhiatr Im S S Korsakova. 2026;126(8):51-58. doi: 10.17116/jnevro202612608151.ABSTRACTOBJECTIVE: To organize and summarize current data on the role of primary motor disorders in the...

RAISR4D Schizophrenia

29/08/2026

Positive and Negative Symptoms Changes in Schizophrenia Patients on Antipsychotic Treatment: a Systematic Review and Dose-Response Meta-analysis

Schizophr Bull. 2026 Aug 20;52(5):sbag077. doi: 10.1093/schbul/sbag077.ABSTRACTBACKGROUND AND HYPOTHESIS: Positive and negative symptoms are core features of schizophrenia and key indicators of antipsychotic efficacy. We...

RAISR4D Schizophrenia

29/08/2026

Delayed Diabetes Treatment and Persistent Hyperglycemia among Individuals with Schizophrenia: a Nationwide Register-Based Study

Schizophr Bull. 2026 Aug 20;52(5):sbag147. doi: 10.1093/schbul/sbag147.ABSTRACTBACKGROUND AND HYPOTHESIS: Individuals with schizophrenia are at increased risk of type 2 diabetes and diabetes-related complications. Whether the...

RAISR4D Schizophrenia

29/08/2026

Intellectual and developmental disability diagnoses in California delivery records and adverse maternal outcomes

Pregnancy (Hoboken). 2026 Aug 28;2(5):e70435. doi: 10.1002/pmf2.70435. eCollection 2026 Sep.ABSTRACTBACKGROUND: Women with intellectual and developmental disability (IDD) are a population whose maternal health outcomes remain...

RAISR4D Schizophrenia

Preventing heat-related illness in people with severe and persistent mental illness: a quality improvement educational intervention

J Clim Chang Health. 2026 Aug 18;31:100726. doi: 10.1016/j.joclim.2026.100726. eCollection 2026 Sep-Oct.ABSTRACTBACKGROUND: Climate change poses severe health risks to people with severe and persistent mental...

RAISR4D Schizophrenia

An unprecedented pan-brachial injury: A case report of ipsilateral floating shoulder, floating elbow, and acetabular fracture following a psychosis-induced fall

Trauma Case Rep. 2026 Aug 6;65:101416. doi: 10.1016/j.tcr.2026.101416. eCollection 2026 Oct.ABSTRACTINTRODUCTION: High-energy trauma can result in complex orthopedic injury patterns. The "floating shoulder" and "floating...

RAISR4D Schizophrenia

Learner experiences of a carer-focused massive open online course on psychosis: A qualitative study

Digit Health. 2026 Aug 25;12:20552076261470199. doi: 10.1177/20552076261470199. eCollection 2026 Jan-Dec.ABSTRACTBACKGROUND: People supporting individuals with psychotic disorders play a vital role in community-based mental health care...

RAISR4D Schizophrenia

Incidence of clozapine-associated neutropenia in patients with schizophrenia: 20-year population-based study in Hong Kong

Br J Psychiatry. 2026 Aug 28:1-8. doi: 10.1192/bjp.2026.10726. Online ahead of print.ABSTRACTBACKGROUND: Clozapine is the gold standard for treatment-resistant schizophrenia, but its use is constrained...

RAISR4D Schizophrenia

Higher frequencies of CNV deletions in bipolar disorder among Chinese Population

Mol Psychiatry. 2026 Aug 27. doi: 10.1038/s41380-026-03853-4. Online ahead of print.ABSTRACTAlthough copy number variants (CNVs) represent well-established genetic contributors to schizophrenia (SCZ), their role in...

RAISR4D Schizophrenia

Diversity of Layer 3 Pyramidal Neuron Properties Across Areas of the Primate Neocortex

Biol Psychiatry. 2026 Aug 27:S0006-3223(26)01495-2. doi: 10.1016/j.biopsych.2026.08.015. Online ahead of print.ABSTRACTImpaired activation of cortical circuits might contribute to working memory deficits in schizophrenia. In this...

RAISR4D Schizophrenia

The embodied self in psychosis: Relationships among insula functional connectivity and emotional embodiment in schizophrenia-spectrum disorders

Schizophr Res. 2026 Aug 27;297:241-253. doi: 10.1016/j.schres.2026.08.013. Online ahead of print.ABSTRACTBACKGROUND: Disturbances in the self are central to schizophrenia-spectrum disorders (SZ) and may arise from...

RAISR4D Schizophrenia

Association between opioid agonist therapy and pharmacotherapy for mental disorders among people living with HIV and co-occurring opioid use and mental disorders

Int J Drug Policy. 2026 Aug 27;157(Pt A):105477. doi: 10.1016/j.drugpo.2026.105477. Online ahead of print.ABSTRACTBACKGROUND: People living with HIV (PLWH) with co-occurring opioid use disorder (OUD)...

RAISR4D Schizophrenia

KPNA1/importin α5 localizes to the nucleolus and associates with box C/D snoRNP complexes

Biochem Biophys Res Commun. 2026 Aug 25;834:154505. doi: 10.1016/j.bbrc.2026.154505. Online ahead of print.ABSTRACTKPNA1 (karyopherin α1, also known as importin α5) is a well-characterized nuclear transport...

RAISR4D Schizophrenia