Schizophrenia – Page 2 – Psychiatry AI: Real-Time AI Scoping Review

RAISR4D Schizophrenia

24/08/2026

Risk of schizophrenia in the offspring of mothers with diabetes during pregnancy: systematic review and meta-analysis

Braz J Psychiatry. 2026 Aug 22. doi: 10.47626/1516-4446-2026-5019. Online ahead of print.ABSTRACTOBJECTIVES: Hyperglycemia during pregnancy is related to adverse obstetric, neonatal, and long-term health outcomes...

RAISR4D Schizophrenia

24/08/2026

Quality of life assessment in individuals with schizophrenia: a COSMIN-based systematic review of S-QoL41 and S-QoL18 incorporating neurobiological support

EClinicalMedicine. 2026 Aug 15;99:104152. doi: 10.1016/j.eclinm.2026.104152. eCollection 2026 Sep.ABSTRACTBACKGROUND: Quality of life is a key outcome in schizophrenia, requiring valid patient-reported outcome measures. We evaluated...

RAISR4D Schizophrenia

24/08/2026

Executive dysfunction and cognitive disorganization in schizophrenia: Case-control and cluster analyses of a Korean Wisconsin Card Sorting Test cohort

Schizophr Res Cogn. 2026 Aug 13;46:100459. doi: 10.1016/j.scog.2026.100459. eCollection 2026 Sep.ABSTRACTOBJECTIVE: Executive dysfunction is a hallmark cognitive deficit in schizophrenia, yet phenotypic heterogeneity within the...

RAISR4D Schizophrenia

24/08/2026

Anticholinergic burden and its predictors among patients with schizophrenia in Northwest Ethiopia: An institutional-based cross sectional study

Ther Adv Psychopharmacol. 2026 Aug 21;16:20451253261481515. doi: 10.1177/20451253261481515. eCollection 2026.ABSTRACTBACKGROUND: Many drugs prescribed for individuals with schizophrenia have anticholinergic effects. When these medications are used...

RAISR4D Schizophrenia

24/08/2026

Machine Learning-Based Discrimination of Treatment-Resistant Schizophrenia Using Structural Brain Imaging: A Multi-Site Proof-of-Concept Study

Biol Psychiatry. 2026 Aug 22:S0006-3223(26)01489-7. doi: 10.1016/j.biopsych.2026.08.009. Online ahead of print.ABSTRACTBACKGROUND: Treatment-resistant schizophrenia (TRS) affects 20-30% of individuals with schizophrenia, with persistent symptoms, functional impairment,...

RAISR4D Schizophrenia

24/08/2026

Recovery through performance: A virtual drama therapy program for clubhouse members with serious mental illness

Psychiatry Res. 2026 Aug 14;365:117390. doi: 10.1016/j.psychres.2026.117390. Online ahead of print.ABSTRACTDespite advancements in psychiatry, individuals with serious mental illness (SMI), such as schizophrenia, major depressive...

RAISR4D Schizophrenia

24/08/2026

Distinctive lexical profiles in Korean-speaking patients with schizophrenia: Analysis of verbal productivity, lexical diversity, and part-of-speech distributions

Psychiatry Res. 2026 Aug 17;365:117402. doi: 10.1016/j.psychres.2026.117402. Online ahead of print.ABSTRACTBACKGROUND: Language disturbance is a core feature of schizophrenia, yet most linguistic research has been...

RAISR4D Schizophrenia

22/08/2026

HD-tDCS modulation of the DLPFC-HPC-EC pathway to enhance working memory in schizophrenia: a TMS-EEG Study

Mol Psychiatry. 2026 Aug 21. doi: 10.1038/s41380-026-03835-6. Online ahead of print.ABSTRACTSchizophrenia (SCZ) is characterized by cognitive impairments, particularly in working memory (WM), which significantly impact...

RAISR4D Schizophrenia

22/08/2026

Writing when writhing with psychosis: a computational linguistic autopsy of Vaslav Nijinsky’s diary

Med Humanit. 2026 Aug 21:medhum-2026-014121. doi: 10.1136/medhum-2026-014121. Online ahead of print.ABSTRACT'God of Dance' Vaslav Nijinsky wrote profusely during a short period in 1918-1919, immediately preceding...

RAISR4D Schizophrenia

21/08/2026

‘I just want an explanation’: A qualitative investigation of how people with psychosis make sense of their visual hallucinations

Psychol Psychother. 2026 Aug 21. doi: 10.1111/papt.70074. Online ahead of print.ABSTRACTOBJECTIVES: Visual hallucinations (visions) in people with psychosis are common and often distressing. Cognitive theory...

RAISR4D Schizophrenia

21/08/2026

Neurological soft signs in patients with treatment-resistant schizophrenia and their relationship with symptoms, premorbid adjustment, and functioning: a comparative study

Nord J Psychiatry. 2026 Aug 21:1-9. doi: 10.1080/08039488.2026.2720107. Online ahead of print.ABSTRACTBACKGROUND AND OBJECTIVES: Motor alterations in schizophrenia are important because they provide measurable, objective...

RAISR4D Schizophrenia

21/08/2026

Improvement of Multifactorial Tremor in Klinefelter Syndrome With Testosterone Replacement Therapy

Case Rep Endocrinol. 2026 Aug 20;2026:8988814. doi: 10.1155/crie/8988814. eCollection 2026.ABSTRACTA man in his 50s with long-standing learning difficulties and schizophrenia currently treated with clozapine presented...

RAISR4D Schizophrenia

21/08/2026

Was Kraepelin Prescient Regarding Excitation-Inhibition Imbalance in Schizophrenia?

Schizophr Bull Open. 2026 Aug 5;7(1):sgag032. doi: 10.1093/schizbullopen/sgag032. eCollection 2026.ABSTRACTResearch on schizophrenia increasingly highlights altered excitation-inhibition regulation in cortical circuits. Excitatory Glutamatergic pyramidal cells propagate...

RAISR4D Schizophrenia

21/08/2026

Use of Electroconvulsive Therapy for Treatment-Resistant Schizophrenia in a Patient Unable to Tolerate Clozapine Due to Clozapine-Associated Hyponatremia: A Case Report

Case Rep Psychiatry. 2026 Aug 20;2026:6269931. doi: 10.1155/crps/6269931. eCollection 2026.ABSTRACTClozapine is regarded as the most effective treatment for patients with treatment-resistant schizophrenia (TRS). However, serious...

RAISR4D Schizophrenia

21/08/2026

A vicious cycle of microglial dysfunction: bridging synaptic pruning and neuroinflammation across the neurodevelopmental continuum

Front Immunol. 2026 Aug 6;17:1883650. doi: 10.3389/fimmu.2026.1883650. eCollection 2026.ABSTRACTRather than viewing classical neurodevelopmental disorders (NDDs) such as autism spectrum disorder (ASD) and severe psychiatric illnesses...

RAISR4D Schizophrenia

21/08/2026

Implementing shared decision-making for hospitalized patients with schizophrenia: a qualitative study of nurse and patient perspectives

Front Psychiatry. 2026 Aug 6;17:1873569. doi: 10.3389/fpsyt.2026.1873569. eCollection 2026.ABSTRACTBACKGROUND: Shared decision-making (SDM) is fundamental to person-centered psychiatry, yet its implementation in schizophrenia care remains limited...

RAISR4D Schizophrenia

21/08/2026

Neurophysiological and autonomic effects of Cognitive Remediation Therapy in schizophrenia: a randomized controlled EEG-GSR study

BMC Psychiatry. 2026 Aug 17;26(1):649. doi: 10.1186/s12888-026-08491-2.ABSTRACTBACKGROUND: Cognitive impairment and emotion dysregulation are core features of schizophrenia and remain insufficiently addressed by pharmacological treatment. Cognitive...

RAISR4D Schizophrenia

21/08/2026

Distinguishing different psychiatric disorders using DDx-PRS

Nat Genet. 2026 Aug 20. doi: 10.1038/s41588-026-02684-x. Online ahead of print.ABSTRACTDespite great progress on case-control polygenic prediction, an unmet need remains for a method that...

RAISR4D Schizophrenia

21/08/2026

Atieh Schizophrenia EEG, a novel high-quality dataset designed to advance biomarker and machine learning research

Sci Data. 2026 Jul 31;13(1):1211. doi: 10.1038/s41597-026-07968-9.ABSTRACTObjective, quantifiable electroencephalogram (EEG) biomarkers and machine learning systems for schizophrenia (SZ) research are limited by the scarcity of...

RAISR4D Schizophrenia

20/08/2026

Translating social incentive deficits in treatment-resistant schizophrenia into rehabilitation targets

Psychiatry Clin Neurosci. 2026 Aug 20. doi: 10.1111/pcn.70120. Online ahead of print.ABSTRACTThis article relates to Translating social incentive deficits in treatment-resistant schizophrenia into rehabilitation targets.PMID:42622337...

RAISR4D Schizophrenia

20/08/2026

Comparison of delusional disorder and schizophrenia in cases lacking criminal responsibility: Sociodemographic, clinical and offense-related characteristics

J Forensic Sci. 2026 Aug 20. doi: 10.1111/1556-4029.70454. Online ahead of print.ABSTRACTCriminal responsibility can be significantly impaired by psychotic disorders. Although delusional disorder (DD) is...

RAISR4D Schizophrenia

20/08/2026

Examining the relationship between schizophrenia and substance use disorders

Psychiatr Danub. 2026 Apr;38(1):226.NO ABSTRACTPMID:42621817

RAISR4D Schizophrenia

20/08/2026

Mitochondrial dysfunction in schizophrenia and psychotic disorders: Implications for antipsychotic drug mechanisms

Psychiatr Danub. 2026 Apr;38(1):147-154. doi: 10.24869/psyd.2026.147.ABSTRACTBACKGROUND: Schizophrenia (SCH) is a severe neuropsychiatric disorder associated with complex neurobiological alterations and suboptimal therapeutic outcomes. Increasing evidence indicates...

RAISR4D Schizophrenia

20/08/2026

The Relationship Between Schizotypy and Latent Inhibition and Conditioned Inhibition

Schizophr Bull Open. 2026 Jul 31;7(1):sgag031. doi: 10.1093/schizbullopen/sgag031. eCollection 2026.ABSTRACTThe Salience Hypothesis suggests that people high in symptoms of schizophrenia aberrantly assign salience. Studies of...

RAISR4D Schizophrenia

20/08/2026

Aberrant network topology of cortical-subcortical circuits in schizophrenia and bipolar disorder: a graph theory study

Front Psychiatry. 2026 Aug 5;17:1919266. doi: 10.3389/fpsyt.2026.1919266. eCollection 2026.ABSTRACTBACKGROUND: Schizophrenia (SCH) or bipolar disorder (BD) patients exhibit a variety of abnormalities in brain network organization...

RAISR4D Schizophrenia

20/08/2026

Soluble urokinase plasminogen activator receptor – What are the clinical potentials in psychiatry?

Brain Behav Immun Health. 2026 Aug 10;56:101329. doi: 10.1016/j.bbih.2026.101329. eCollection 2026 Oct.ABSTRACTBACKGROUND: Mental disorders have been associated with systemic chronic inflammation, and conditions such as...

RAISR4D Schizophrenia

20/08/2026

The mechanism of action and clinical efficacy of xanomeline-trospium in schizophrenia: A comprehensive review

Ther Adv Psychopharmacol. 2026 Aug 18;16:20451253261478086. doi: 10.1177/20451253261478086. eCollection 2026.ABSTRACTThis narrative review summarizes the latest clinical evidence on xanomeline-trospium in schizophrenia, a first-in-class centrally acting...

RAISR4D Schizophrenia

20/08/2026

AI-powered cognitive remediation for schizophrenia: a psychologist’s lens on evidence and scalability in India

Front Psychol. 2026 Aug 5;17:1873888. doi: 10.3389/fpsyg.2026.1873888. eCollection 2026.ABSTRACTBACKGROUND: Schizophrenia spectrum disorders (SSDs) are marked by cognitive deficits, functional impairment, and notable treatment gap in...

RAISR4D Schizophrenia

20/08/2026

Prevalence of Childhood Adversity and Its Association with Depression, Anxiety, and Psychotic-like Experiences Among Young Indian Adults: A Cross-sectional Study

Indian J Psychol Med. 2026 Aug 18:02537176261474726. doi: 10.1177/02537176261474726. Online ahead of print.ABSTRACTBACKGROUND: Childhood adversity is very common and strongly linked to poor mental health;...

RAISR4D Schizophrenia

20/08/2026

Exome sequencing and metabolite profiling identifies genetic variants associated with altered metabolism in early-onset schizophrenia

iScience. 2026 Aug 11;29(8):117123. doi: 10.1016/j.isci.2026.117123. eCollection 2026 Aug 21.ABSTRACTEarly-onset schizophrenia (EOS) is a severe psychiatric disorder characterized by strong genetic contribution and metabolic alterations,...

RAISR4D Schizophrenia

20/08/2026

Systematic profiling reveals broad G protein coupling and context-dependent modulation of cyclic AMP by the orphan receptor GPR139

Br J Pharmacol. 2026 Aug 20. doi: 10.1111/bph.70606. Online ahead of print.ABSTRACTBACKGROUND AND PURPOSE: G protein-coupled receptors (GPCRs) are major drug targets, yet many orphan...

RAISR4D Schizophrenia

20/08/2026

Optimization of hospitalization duration and cost structure for chronic schizophrenia patients in psychiatric hospitals

Curr Med Res Opin. 2026 Aug 19:1-13. doi: 10.1080/03007995.2026.2719084. Online ahead of print.ABSTRACTOBJECTIVE: Chronic schizophrenia patients in psychiatric hospitals often have prolonged stays, high insurance...

RAISR4D Schizophrenia

20/08/2026

Trace Elements Genetics: A Potential Role in Treatment-Resistant Major Psychoses and Related Traits?

Am J Med Genet B Neuropsychiatr Genet. 2026 Aug 19. doi: 10.1002/ajmg.b.70030. Online ahead of print.ABSTRACTTrace elements are pivotal to key biological processes, with possible...

RAISR4D Schizophrenia

20/08/2026

Human organoids that mimic brain development grown for years in lab

Nature. 2026 Aug 19. doi: 10.1038/d41586-026-02585-3. Online ahead of print.NO ABSTRACTPMID:42618615 | DOI:10.1038/d41586-026-02585-3

RAISR4D Schizophrenia

19/08/2026

Prevalence and Incidence of Dementia for Schizophrenia and Other Primary Psychotic Disorders: A Systematic Review and Meta-Analysis

Asia Pac Psychiatry. 2026 Sep;18(3):e70033. doi: 10.1111/appy.70033.ABSTRACTPeople with psychotic disorders have higher dementia risk. This study aimed to investigate the prevalence and incidence of dementia...

RAISR4D Schizophrenia

19/08/2026

Potential Mechanisms of Change in Virtual Reality-based Cognitive Behavioural Therapy and Standard Cognitive Behavioural Therapy for Schizophrenia-Related Paranoia: A Mediation Analysis from the FaceYourFears Trial

Schizophr Bull Open. 2026 Jul 21;7(1):sgag028. doi: 10.1093/schizbullopen/sgag028. eCollection 2026.ABSTRACTBACKGROUND AND HYPOTHESIS: Cognitive models conceptualize paranoia in schizophrenia spectrum disorders as driven and maintained by...

RAISR4D Schizophrenia

19/08/2026

Immunometabolic reprogramming of central and peripheral immune cells in mental disorders: mechanisms and therapeutic implications

Front Immunol. 2026 Aug 4;17:1712425. doi: 10.3389/fimmu.2026.1712425. eCollection 2026.ABSTRACTImmune cells are those involved in or related to immune responses, found throughout immune organs and the...

RAISR4D Schizophrenia

19/08/2026

Cariprazine and Lithium Overdose: A Case Report

Cureus. 2026 Jul 19;18(7):e112941. doi: 10.7759/cureus.112941. eCollection 2026 Jul.ABSTRACTCariprazine is a third-generation antipsychotic used in the treatment of schizophrenia and bipolar affective disorder. This case...

RAISR4D Schizophrenia

19/08/2026

Corrigendum to “exploratory anchor-based analyses to determine minimal clinically important differences for the brief assessment of cognition in schizophrenia and the schizophrenia cognition rating scale” [Schizophr. Res. 2026 July 25. doi:10.1016/j.schres.2026.07.021. Epub ahead of print]

Schizophr Res. 2026 Aug 18:S0920-9964(26)00258-6. doi: 10.1016/j.schres.2026.08.007. Online ahead of print.NO ABSTRACTPMID:42613287 | DOI:10.1016/j.schres.2026.08.007

RAISR4D Schizophrenia

19/08/2026

The impact of the motherhood role on recovery motivation in women with severe mental illness

Ann Med. 2026 Dec;58(1):2714593. doi: 10.1080/07853890.2026.2714593. Epub 2026 Aug 18.ABSTRACTOBJECTIVE: This study aimed to examine the association between maternal role perceptions and subjective recovery motivation...

RAISR4D Schizophrenia

14/08/2026

The Search for Associations of Polymorphic Variants of the COMT and MAOA Genes with Suicide Attempts in Patients with Schizophrenia: A Pilot Study

Mol Biol (Mosk). 2026 May-Jun;60(3):457-473. doi: 10.7868/S3034555326030061.ABSTRACTThe main causes of early mortality in patients with schizophrenia are comorbid somatic diseases (primarily cardiovascular diseases, diabetes, and...

RAISR4D Schizophrenia

14/08/2026

The Search for Associations of Polymorphic Variants of the COMT and MAOA Genes with Suicide Attempts in Patients with Schizophrenia: A Pilot Study

Mol Biol (Mosk). 2026 May-Jun;60(3):457-473. doi: 10.7868/S3034555326030061.ABSTRACTThe main causes of early mortality in patients with schizophrenia are comorbid somatic diseases (primarily cardiovascular diseases, diabetes, and...

RAISR4D Schizophrenia

14/08/2026

From molecules to minds: Integrative multi-omics in psychiatry

J Mood Anxiety Disord. 2026 Jul 29;15:100194. doi: 10.1016/j.xjmad.2026.100194. eCollection 2026 Sep.ABSTRACTPsychiatric disorders are biologically complex conditions arising from interactions across genomic, epigenomic, transcriptomic, proteomic,...

RAISR4D Schizophrenia

14/08/2026

Structure-Affinity Relationship Optimization of SYA16263 Yields New Ligands with Improved Receptor Affinity and Antipsychotic-Like Properties

ACS Omega. 2026 Jul 20;11(31):46009-46029. doi: 10.1021/acsomega.6c02255. eCollection 2026 Aug 11.ABSTRACTCentral nervous system (CNS) disorders are multifactorial in nature. Dopamine (DA) and serotonin (5-HT) receptors...

RAISR4D Schizophrenia

14/08/2026

Temporal Dynamics of Reward Dysfunction in Psychiatric Disorders: Memory-Derived Value, Incentive Salience, Hedonic Impact, and Value Updating

Biol Psychiatry Glob Open Sci. 2026 Jul 4;6(5):100786. doi: 10.1016/j.bpsgos.2026.100786. eCollection 2026 Sep.ABSTRACTReward processing unfolds across time: Prior experiences shape cue valuation and motivation, anticipated...

RAISR4D Schizophrenia

14/08/2026

Persistence targeted smoking cessation for smokers with schizophrenia or schizoaffective disorder: a feasibility study

J Smok Cessat. 2020 Sep;15(3):157-162. doi: 10.1017/jsc.2020.19. Epub 2020 Jul 9.ABSTRACTINTRODUCTION: Individuals with schizophrenia are more likely to smoke and less likely to quit smoking...

RAISR4D Schizophrenia

14/08/2026

Chronic pain and its correlation with quality of life in hospitalized stable patients with schizophrenia: a cross-sectional survey in Southern Sichuan, China

Front Psychiatry. 2026 Jul 30;17:1772799. doi: 10.3389/fpsyt.2026.1772799. eCollection 2026.ABSTRACTThe complex paradox of pain perception in schizophrenia often leads to under recognition of chronic pain in...

RAISR4D Schizophrenia

14/08/2026

Early Changes in Composite Insulin-Resistance Indices After Adjunctive Probiotic Treatment in Olanzapine-Treated Schizophrenia: A Longitudinal Secondary Analysis

Int J Psychiatry Med. 2026 Aug 14:912174261474760. doi: 10.1177/00912174261474760. Online ahead of print.ABSTRACTObjectiveOlanzapine is effective for schizophrenia but commonly causes metabolic dysregulation. This study examined...

RAISR4D Schizophrenia

13/08/2026

Mental illness among persons with and without dementia in continuing care: A multi-jurisdictional, repeated cross-sectional study

J Alzheimers Dis. 2026 Aug 13:13872877261476238. doi: 10.1177/13872877261476238. Online ahead of print.ABSTRACTBackgroundLimited epidemiologic data exists for mental illnesses among at-risk home care (HC) and residential...

RAISR4D Schizophrenia

13/08/2026

Neutrophil-to-lymphocyte ratio and metabolic syndrome in patients with schizophrenia spectrum disorders

Med Glas (Zenica). 2026 Aug 7;23(2). doi: 10.17392/medglas-2197-23-2.ABSTRACTAIM: To investigate the differences in neutrophil-to-lymphocyte ratio (NLR) between patients with schizophrenia spectrum disorders (SSD) and healthy...

RAISR4D Schizophrenia

13/08/2026

Relapse rates and associated factors in patients with schizophrenia: a retrospective study from Brcko District, Bosnia and Herzegovina

Med Glas (Zenica). 2026 Jul 21;23(2). doi: 10.17392/medglas-2172-23-2.ABSTRACTAIM: To determine the proportion of patients with recorded psychiatric rehospitalisation within one year and examine crude associations...

RAISR4D Schizophrenia

13/08/2026

Deaths in mental health care in Australia: an analysis of coroners’ reports

Psychiatr Psychol Law. 2025 May 25;33(4):1139-1156. doi: 10.1080/13218719.2025.2497788. eCollection 2026.ABSTRACTDeaths in mental health care are often the subject of a coronial inquest, yet they remain...

RAISR4D Schizophrenia

13/08/2026

Reliability of psychiatric diagnoses in the 21st century

Front Psychiatry. 2026 Jul 29;17:1891625. doi: 10.3389/fpsyt.2026.1891625. eCollection 2026.ABSTRACTBACKGROUND: Reliable diagnosis is a cornerstone of medical practice, yet concerns about diagnostic reliability have long haunted...

RAISR4D Schizophrenia

13/08/2026

Possible Improvement of Tardive Dyskinesia and Negative Symptoms With Lurasidone Augmentation in a Treatment-Resistant Schizophrenia Patient

Case Rep Psychiatry. 2026 Aug 11;2026:7121649. doi: 10.1155/crps/7121649. eCollection 2026.ABSTRACTTardive dyskinesia (TD) is a cluster of symptoms affecting orofacial, truncal, and extremity regions following prolonged...

RAISR4D Schizophrenia

13/08/2026

Developing a comprehensive scale for measuring explanatory models of mental disorders among Japanese adults

Front Psychol. 2026 Jul 29;17:1834088. doi: 10.3389/fpsyg.2026.1834088. eCollection 2026.ABSTRACTINTRODUCTION: Individuals differ in their understanding of the causes of illnesses or problems and the appropriate methods...

RAISR4D Schizophrenia

13/08/2026

Intracranial Candida parapsilosis infection occurring 2 years after burr-hole drainage for chronic subdural hematoma: a case report

Br J Biomed Sci. 2026 Jul 29;83:16761. doi: 10.3389/bjbs.2026.16761. eCollection 2026.ABSTRACTBACKGROUND: Chronic subdural hematoma (CSDH) is a common condition affecting patients undergoing neurosurgical treatment for...

RAISR4D Schizophrenia

13/08/2026

DNMT1 as an environmental sensor: epigenetic pathways linking environmental exposures, sex hormone signaling, and vulnerability to neurodevelopmental and neurodegenerative diseases

Front Neurol. 2026 Jul 29;17:1883887. doi: 10.3389/fneur.2026.1883887. eCollection 2026.ABSTRACTDNA methyltransferase 1 (DNMT1) has classically been viewed as the canonical maintenance methyltransferase, yet accumulating evidence positions...

RAISR4D Schizophrenia

13/08/2026

Lurasidone hydrochloride-loaded microparticle-based long-acting injectable: formulation optimisation, characterisation, and payload release kinetics-a proof of concept study

J Microencapsul. 2026 Aug 13:1-16. doi: 10.1080/02652048.2026.2708740. Online ahead of print.ABSTRACTLurasidone hydrochloride is a promising antipsychotic agent. The currently marketed formulation (Latuda®) of lurasidone hydrochloride...

RAISR4D Schizophrenia

12/08/2026

Impact of adjunctive dihydropyridine calcium channel blockers on mental health outcomes in people with severe mental illness: A target trial emulation in English electronic health records

J Psychopharmacol. 2026 Aug 12:2698811261473408. doi: 10.1177/02698811261473408. Online ahead of print.ABSTRACTBACKGROUND: Dihydropyridine calcium channel blockers have been implicated in both symptom improvement and exacerbation in...

RAISR4D Schizophrenia

12/08/2026

Substance Use Patterns in Pediatric Solid Organ Transplant Candidates: Impact After Transplant

Pediatr Transplant. 2026 Aug;30(8):e70427. doi: 10.1111/petr.70427.ABSTRACTBACKGROUND: The prevalence and impact of substance use in pediatric solid organ transplant candidates and how these relate to post-transplant...

RAISR4D Schizophrenia

12/08/2026

Disease-Specific Glycopattern Signatures of Serum Small Extracellular Vesicles in Depression, Schizophrenia, and Glioblastoma

Proteomics. 2026 Aug 12:e70170. doi: 10.1002/pmic.70170. Online ahead of print.ABSTRACTSerum small extracellular vesicles (sEVs) carry glycoproteins that reflect the pathophysiological states of their cells of...

RAISR4D Schizophrenia

12/08/2026

Psychobiotic Strategies for Managing Anxiety, Depression, and Schizophrenia: A Narrative Review

J Restor Med. 2026 Jul;2026. doi: 10.14200/jrm.2026.0002. Epub 2026 Jul 28.ABSTRACTThe gut microbiome exerts significant influence over mental health through the bidirectional communication network of...

RAISR4D Schizophrenia

12/08/2026

Oxidative Damage Induced Disruption of Mitochondrial Quality Control Underlying Abnormal Energy Metabolism in Peripheral Leukocytes of Schizophrenia Patients

Schizophr Bull Open. 2026 Jul 26;7(1):sgag029. doi: 10.1093/schizbullopen/sgag029. eCollection 2026.ABSTRACTBACKGROUND AND HYPOTHESIS: Mitochondrial dysfunction is increasingly implicated in schizophrenia (SZ) pathogenesis. To maintain mitochondrial homeostasis...

RAISR4D Schizophrenia

12/08/2026

Genetic variants in purine metabolism and treatment resistance in schizophrenia: evidence supporting the adenosine hypothesis – a pilot study

Front Pharmacol. 2026 Jul 28;17:1876365. doi: 10.3389/fphar.2026.1876365. eCollection 2026.ABSTRACTBACKGROUND: The adenosine hypothesis of schizophrenia provides an integrative framework in which reduced adenosinergic signalling contributes to...

RAISR4D Schizophrenia

12/08/2026

Case Report: Severe adolescent-onset schizophrenia with Capgras syndrome and remission during clozapine-centered treatment after earthquake-related displacement and peer victimization

Front Psychiatry. 2026 Jul 28;17:1887119. doi: 10.3389/fpsyt.2026.1887119. eCollection 2026.ABSTRACTAdolescent first-episode psychosis may combine schizophrenia-spectrum, affective, trauma-related, and developmental features, and Capgras syndrome is uncommon in...

RAISR4D Schizophrenia

12/08/2026

Individual factors associated with physical activity adherence in schizophrenia: an exploratory secondary analysis of two randomized controlled trials

Front Psychol. 2026 Jul 28;17:1878217. doi: 10.3389/fpsyg.2026.1878217. eCollection 2026.ABSTRACTINTRODUCTION: Physical activity is an effective adjunctive therapy in schizophrenia, improving psychiatric symptoms and reducing the mortality...

RAISR4D Schizophrenia

12/08/2026

Retraction notice to “Metabolic effects and clinical outcomes of olanzapine in schizophrenia: A systematic review and meta-analysis” [Heliyon 10 (2024) e40424]

Heliyon. 2025 Dec 18;12(1):e44372. doi: 10.1016/j.heliyon.2025.e44372. eCollection 2026 Jan.ABSTRACT[This retracts the article DOI: 10.1016/j.heliyon.2024.e40424.].PMID:42581924 | PMC:PMC13455927 | DOI:10.1016/j.heliyon.2025.e44372

RAISR4D Schizophrenia

12/08/2026

Institutional and home living status in schizophrenia: Associations with functioning, childhood trauma, and symptom severity

Australas Psychiatry. 2026 Aug 11:10398562261476921. doi: 10.1177/10398562261476921. Online ahead of print.ABSTRACTIntroductionResidential status has been associated with clinical and functional outcomes in schizophrenia, yet its interaction...

RAISR4D Schizophrenia

12/08/2026

Genome-wide meta-analysis with 1,590,596 individuals identifies 12 novel risk loci for systemic lupus erythematosus

Mamm Genome. 2026 Aug 11;37(1):95. doi: 10.1007/s00335-026-10266-9.ABSTRACTSystemic lupus erythematosus (SLE) is a chronic life-threatening and relapsing-remitting multisystem autoimmune disease. However, the genetic susceptibility of SLE...

RAISR4D Schizophrenia

12/08/2026

A Physical Exercise Program Significantly Boosts the Impact of Cognitive Training on Attention Deficits After a First Episode of Schizophrenia

Schizophr Bull. 2026 Jul 3;52(4):sbag136. doi: 10.1093/schbul/sbag136.ABSTRACTBACKGROUND AND HYPOTHESIS: Our initial smaller study and other recent research suggest that adding a physical exercise program to...

RAISR4D Schizophrenia

11/08/2026

Transdiagnostic determinants of Growth Differentiation Factor-15 (GDF-15) in psychiatric in-patients: age, renal indices, interleukin-6 (IL-6) and soluble urokinase plasminogen activator receptor (suPAR)

Brain Behav Immun Health. 2026 Jul 23;56:101312. doi: 10.1016/j.bbih.2026.101312. eCollection 2026 Oct.ABSTRACTGrowth differentiation factor-15 (GDF-15) is a stress-responsive cytokine implicated in systemic inflammatory and renal...

RAISR4D Schizophrenia

11/08/2026

Midlife women miss out: RANZCP treatment guidelines for schizophrenia should consider the lifestage needs of midlife women

Aust N Z J Psychiatry. 2026 Aug 11:48674261476547. doi: 10.1177/00048674261476547. Online ahead of print.ABSTRACTMidlife women are given no specific mention in the recently published Grading...

RAISR4D Schizophrenia

11/08/2026

Spine nanostructure profiling of cultured neurons from mouse models reveals a schizophrenia-linked role for Ecrg4

Elife. 2026 Aug 11;14:RP109083. doi: 10.7554/eLife.109083.ABSTRACTDendritic spine dysfunction may contribute to the etiology and symptom expression of neuropsychiatric disorders. The intimate relationship between spine morphology...

RAISR4D Schizophrenia

11/08/2026

ADAR-mediated RNA editing in CNS disorders: from pathogenic mechanisms to therapeutic opportunities

Cell Mol Biol Lett. 2026 Jul 25;31(1):130. doi: 10.1186/s11658-026-00995-9.ABSTRACTThe adenosine deaminases acting on RNA (ADAR) family of enzymes (ADAR1 and ADAR2) catalyze adenosine-to-inosine (A-to-I) RNA...

RAISR4D Schizophrenia

10/08/2026

Causes of death and mortality patterns in clozapine-treated patients: 17-year retrospective cohort study

BJPsych Open. 2026 Aug 10;12(5):e213. doi: 10.1192/bjo.2026.12069.ABSTRACTBACKGROUND: Clozapine reduces overall mortality and suicide risk in schizophrenia, but the specific causes and clinical contexts of death...

RAISR4D Schizophrenia

09/08/2026

Apical integration theory provides a neural basis for understanding disorganization and consciousness in the schizophrenias

Curr Res Neurobiol. 2026 Jul 24;11:100165. doi: 10.1016/j.crneur.2026.100165. eCollection 2026 Dec.ABSTRACTRecent discoveries involving pyramidal neurons with two zones of input integration (apical and basal), the...

RAISR4D Schizophrenia

09/08/2026

Investigating the effects of chlorogenic acid on novel object recognition memory impairment, hyperlocomotion, and prefrontal BDNF expression in a sub-chronic ketamine-induced schizophrenia-like rat model

IBRO Neurosci Rep. 2026 Jul 24;21:352-361. doi: 10.1016/j.ibneur.2026.07.010. eCollection 2026 Dec.ABSTRACTSchizophrenia is a severe neuropsychiatric disorder characterized by positive, negative, cognitive, mood-related, and motor symptoms....

RAISR4D Schizophrenia

09/08/2026

Brain-targeted intranasal aripiprazole via modified chitosan nanoparticles: controlled release, pharmacokinetics, and pharmacodynamics

Drug Deliv Transl Res. 2026 Aug 8. doi: 10.1007/s13346-026-02193-8. Online ahead of print.ABSTRACTSchizophrenia remains one of the most disabling mental disorders, and effective therapy is...

RAISR4D Schizophrenia

09/08/2026

Symptom Burden and Quality of Life in Patients With Severe Mental Disorders Initiating Cancer Treatment

Clin Oncol (R Coll Radiol). 2026 Jul 16;58:104301. doi: 10.1016/j.clon.2026.104301. Online ahead of print.ABSTRACTBACKGROUND: Patients with pre-existing severe mental disorders (SMDs), defined as moderate to...

RAISR4D Schizophrenia

09/08/2026

Cognitive-behavioral suicide prevention for psychosis in community mental health: A pilot randomized clinical trial

Schizophr Res. 2026 Aug 8;297:140-148. doi: 10.1016/j.schres.2026.08.001. Online ahead of print.ABSTRACTAdults with schizophrenia spectrum disorders (SSDs) have substantially elevated suicide risk, yet few suicide prevention...

RAISR4D Schizophrenia

09/08/2026

Clinical and Economic Burden of Diseases with Accelerated Approval Therapies: Evidence of Unmet Patient Need

Ther Innov Regul Sci. 2026 Aug 8. doi: 10.1007/s43441-026-01030-x. Online ahead of print.ABSTRACTBACKGROUND: Some US payers delay coverage for non-oncology treatments approved via the Food...

RAISR4D Schizophrenia

09/08/2026

Increased RHOA expression in peripheral blood mononuclear cells of patients with acute schizophrenia

Mol Biol Rep. 2026 Aug 8;53(1):1367. doi: 10.1007/s11033-026-12493-4.ABSTRACTBACKGROUND: RhoA-a member of the Rho family of GTPases-critically regulates synaptic plasticity and immune cell function, which have...

RAISR4D Schizophrenia

08/08/2026

Effect of atenolol versus ivabradine on heart rate variability in patients of schizophrenia with clozapine-induced tachycardia: a randomized controlled trial

Psychiatry Res. 2026 Jul 28;365:117341. doi: 10.1016/j.psychres.2026.117341. Online ahead of print.ABSTRACTBACKGROUND: A third of schizophrenia cases are resistant to antipsychotics, where clozapine is the only...

RAISR4D Schizophrenia

08/08/2026

Thirty years of forensic psychiatric evaluations: Reflections on diagnostic consistency and expert opinion

Leg Med (Tokyo). 2026 Aug 6;85:102951. doi: 10.1016/j.legalmed.2026.102951. Online ahead of print.ABSTRACTForensic psychiatry lacks objective biological markers and relies on clinical methodologies inherently influenced by...

RAISR4D Schizophrenia

08/08/2026

Machine learning-based integration of surface morphometric features identifies diagnostic and symptom-related cortical signatures of schizophrenia

Schizophr Res. 2026 Aug 7;297:120-128. doi: 10.1016/j.schres.2026.07.031. Online ahead of print.ABSTRACTSchizophrenia (SCZ) is associated with widespread cortical abnormalities, however, neuroanatomical markers with robust diagnostic and...

RAISR4D Schizophrenia

08/08/2026

Social functioning and formal thought disorder in schizophrenia: A Bayesian meta-analysis

Schizophr Res. 2026 Aug 7;297:131-139. doi: 10.1016/j.schres.2026.07.028. Online ahead of print.ABSTRACTBACKGROUND: Formal thought disorder (FTD) is a key determinant of social functioning in schizophrenia. However,...

RAISR4D Schizophrenia

07/08/2026

The intervention targets of family functioning and cognitive insight in community-dwelling individuals with schizophrenia: a simulated network analysis

Front Psychiatry. 2026 Jul 23;17:1843768. doi: 10.3389/fpsyt.2026.1843768. eCollection 2026.ABSTRACTBACKGROUND: This study aimed to explore core and bridge elements in the network structure linking family functioning...

RAISR4D Schizophrenia

07/08/2026

Associations among stress perception, clinical symptoms, and hippocampal subfield volumes in first-episode patients with schizophrenia

Front Psychiatry. 2026 Jul 23;17:1885091. doi: 10.3389/fpsyt.2026.1885091. eCollection 2026.ABSTRACTBACKGROUND: Hippocampal neurogenesis shapes adaptation and improves responses to stress. Patients with schizophrenia show marked functional impairment...

RAISR4D Schizophrenia

07/08/2026

From observation to evidence: harnessing the mental status examination as a real-world data source in clinical research

Front Health Serv. 2026 Jul 23;6:1784842. doi: 10.3389/frhs.2026.1784842. eCollection 2026.ABSTRACTBACKGROUND: Electronic health record (EHR) based research using psychiatric real-world data is limited by a lack...

RAISR4D Schizophrenia

06/08/2026

Delusional themes and forensic status in schizophrenia spectrum disorders: a machine learning based discriminative study

Front Psychol. 2026 Jul 22;17:1840906. doi: 10.3389/fpsyg.2026.1840906. eCollection 2026.ABSTRACTBACKGROUND: Schizophrenia spectrum disorders (SSD) are associated with an elevated risk of violent and offending behavior; however,...

RAISR4D Schizophrenia

06/08/2026

Colour preferences among individuals with common mental health disorders: a scoping review

Front Psychol. 2026 Jul 22;17:1832200. doi: 10.3389/fpsyg.2026.1832200. eCollection 2026.ABSTRACTINTRODUCTION: Colours have been used as a complementary aid in the treatment of physical and mental disorders...

RAISR4D Schizophrenia

06/08/2026

Cancer-related mortality among individuals with schizophrenia: systematic review and meta-analysis of cohort studies

BJPsych Open. 2026 Aug 6;12(5):e206. doi: 10.1192/bjo.2026.12068.ABSTRACTBACKGROUND: Individuals with schizophrenia have shown distinct cancer incidence patterns.AIMS: We aimed to assess whether their cancer-related mortality differs...

RAISR4D Schizophrenia

06/08/2026

Dopamine Receptor D2 gene Polymorphisms rs2005313, rs4274224, and rs4938019 in Pakistani Patients with Schizophrenia:a Diagnostic Tool for Schizophrenia

J Mol Neurosci. 2026 Aug 5;76(3):125. doi: 10.1007/s12031-026-02582-1.ABSTRACTBACKGROUND: This study was designed to evaluate the genetic association of three specific intronic Single Nucleotide Polymorphisms (SNPs)...

RAISR4D Schizophrenia

06/08/2026

Accelerated DMN-targeted cTBS improves processing speed deficits in schizophrenia

Mol Psychiatry. 2026 Aug 5. doi: 10.1038/s41380-026-03798-8. Online ahead of print.ABSTRACTCognitive deficits are a leading cause of disability in schizophrenia and are linked to poor...

RAISR4D Schizophrenia

06/08/2026

Reducing mental health stigmatisation among healthcare workers and students using a virtual reality protocol: the VIRTUS protocol, a randomised controlled trial

BMJ Open. 2026 Aug 5;16(8):e111884. doi: 10.1136/bmjopen-2025-111884.ABSTRACTINTRODUCTION: Schizophrenia is a chronic psychiatric disorder, frequently associated with stigma, including within healthcare settings that significantly impairs quality...

RAISR4D Schizophrenia

01/08/2026

Prenatal cannabis exposure affects human fetal neurodevelopment: an integrated multi-omics study

bioRxiv [Preprint]. 2026 Jul 20:2026.07.15.738779. doi: 10.64898/2026.07.15.738779.ABSTRACTPrenatal cannabis use is on the rise, and observational studies suggest that such use results in neurodevelopmental deficits in...

RAISR4D Schizophrenia

31/07/2026

Increased Activity of the Glymphatic System in First-Episode Psychosis: Relationship With Cortical Thinning

JAACAP Open. 2026 Apr 23;4(4):691-700. doi: 10.1016/j.jaacop.2026.04.004. eCollection 2026 Aug.ABSTRACTOBJECTIVE: First-episode psychosis (FEP) in pediatric onset is a pivotal window for preventing chronic disability and...

RAISR4D Schizophrenia

31/07/2026

Holodysphrenia and acute schizophrenia: Professor Barahona Fernandes’s pioneering contribution to the nosology of acute transient psychoses – Psychiatry in history

Br J Psychiatry. 2026 Aug;229(2):252. doi: 10.1192/bjp.2025.10510. Epub 2026 Jul 31.NO ABSTRACTPMID:42533784 | DOI:10.1192/bjp.2025.10510

RAISR4D Schizophrenia

31/07/2026

A Case Report: Cobenfy in a Middle-Aged Man with Schizophrenia

J Am Psychiatr Nurses Assoc. 2026 Jul 31:10783903261473927. doi: 10.1177/10783903261473927. Online ahead of print.ABSTRACTOBJECTIVE: Schizophrenia is a serious mental illness with symptoms that impact mood,...

RAISR4D Schizophrenia

31/07/2026