Category: Substance Use Disorders

J Neurophysiol. 2026 Sep 2. doi: 10.1152/jn.00103.2026. Online ahead of print.ABSTRACTInterneurons in the motor cortex (M1) contribute to key motor functions, which are often altered...

Sante Publique. 2026;38(HS1):181-199. doi: 10.3917/spub.hs1.2026.0181.ABSTRACTINTRODUCTION: In a context in which institutions recommend addressing health challenges through patient engagement, we have chosen to develop and pilot...

BMJ Open. 2026 Aug 31;16(8):e115813. doi: 10.1136/bmjopen-2025-115813.ABSTRACTINTRODUCTION: Autistic children and adolescents (herein, youth) are at 3.5 times greater risk of suicide attempts and deaths than...

Anticancer Res. 2026 Sep;46(9):4859-4865. doi: 10.21873/anticanres.18338.ABSTRACTBACKGROUND/AIM: Approximately 30% of all cancers have mutations in the KRAS proto-oncogene, GTPase (KRAS), and approximately 88% of pancreatic cancer...

Langmuir. 2026 Aug 25;42(33):23931-23942. doi: 10.1021/acs.langmuir.6c02010.ABSTRACTAlthough stainless steel (SS) is widely used for cardiovascular stents, its surface is prone to undesirable biological interactions that contribute...

Neuropharmacology. 2026 Aug 31:111165. doi: 10.1016/j.neuropharm.2026.111165. Online ahead of print.ABSTRACTRelapse triggered by withdrawal memory is the important challenge in addiction therapy, with somatic withdrawal symptoms...

Neuropharmacology. 2026 Aug 31:111160. doi: 10.1016/j.neuropharm.2026.111160. Online ahead of print.ABSTRACTCocaine use disorder is marked by strong interindividual variability, yet the molecular determinants underlying vulnerability in...

Drug Discov Today. 2026 Aug 31:104791. doi: 10.1016/j.drudis.2026.104791. Online ahead of print.ABSTRACTOral drug product development has traditionally been optimized around maximizing mean bioavailability in healthy...

Cell. 2026 Aug 31:S0092-8674(26)00927-X. doi: 10.1016/j.cell.2026.07.058. Online ahead of print.ABSTRACTEndogenous neuropeptides are uniquely poised to regulate neuronal activity and behavior across multiple timescales. Traditional studies...

Eur J Med Chem. 2026 Aug 31;319:119277. doi: 10.1016/j.ejmech.2026.119277. Online ahead of print.ABSTRACTArtificial intelligence (AI) is accelerating antimicrobial peptide (AMP) discovery, but prediction-centered workflows often...

Addict Behav. 2026 Aug 31;184:108844. doi: 10.1016/j.addbeh.2026.108844. Online ahead of print.ABSTRACTMemory loss from alcohol ("blackout") is common among young adults who drink and associated with...

Drug Alcohol Depend. 2026 Aug 27;287:113325. doi: 10.1016/j.drugalcdep.2026.113325. Online ahead of print.ABSTRACTOBJECTIVES: Methamphetamine use disorder (MUD) contributes to postpartum morbidity and mortality. Postpartum progesterone decline...

Nicotine Tob Res. 2026 Aug 31:ntag194. doi: 10.1093/ntr/ntag194. Online ahead of print.ABSTRACTINTRODUCTION: Tobacco and cannabis co-use is an increasingly complex public health challenge shaped by...

Kurume Med J. 2026 Aug 31. doi: 10.2739/kurumemedj.MS7312001. Online ahead of print.ABSTRACTAnger may arise following harmful experiences such as violence, and managing anger may be...

Neuroscience. 2026 Aug 30:S0306-4522(26)00591-9. doi: 10.1016/j.neuroscience.2026.08.049. Online ahead of print.ABSTRACTClassical psychedelics exert therapeutic effects on affective disorders, with serotonin 5-HT2A receptor activation thought to play...

Neuroscience. 2026 Aug 30:S0306-4522(26)00590-7. doi: 10.1016/j.neuroscience.2026.08.047. Online ahead of print.ABSTRACTSubstance use disorder develops in a subset of individuals after repeated drug exposure and is characterized...

Nicotine Tob Res. 2026 Aug 29:ntag189. doi: 10.1093/ntr/ntag189. Online ahead of print.ABSTRACTINTRODUCTION: This study aimed to compare cessation and weight gain among US adults in...

J Mol Histol. 2026 Aug 29;57(5):285. doi: 10.1007/s10735-026-10957-2.ABSTRACTBACKGROUND: Schisandra chinensis polysaccharide (SCP) has demonstrated antidiabetic properties in previous studies; however, the mechanisms underlying its regulation...

ChemMedChem. 2026 Sep 14;21(17):e70442. doi: 10.1002/cmdc.70442.ABSTRACTThe Na+/K+-ATPase (NKA) is a central regulator of cardiac ion homeostasis and a validated target for heart failure. Yet, cardiotonic...

In Vivo. 2026 Sep-Oct;40(5):2663-2669. doi: 10.21873/invivo.14420.ABSTRACTBACKGROUND/AIM: The phosphatidylinositol 3-Kinase (PI3K) pathway is thought to be oncogenic in cancers when it is mutated at various sites....

NASN Sch Nurse. 2026 Aug 28:1942602X261482095. doi: 10.1177/1942602X261482095. Online ahead of print.ABSTRACTExcessive digital technology use among adolescents has become an increasing public health concern, with...

Diabetes Res Clin Pract. 2026 Aug 28:113528. doi: 10.1016/j.diabres.2026.113528. Online ahead of print.ABSTRACTAIMS: To provide evidence-based recommendations for integrating smoking cessation into the prevention and...

J Subst Use Addict Treat. 2026 Aug 28:210103. doi: 10.1016/j.josat.2026.210103. Online ahead of print.ABSTRACTINTRODUCTION: Current best practice is for primary care physicians (PCPs) to screen...

Spectrochim Acta A Mol Biomol Spectrosc. 2026 Aug 26;364(Pt 2):128657. doi: 10.1016/j.saa.2026.128657. Online ahead of print.ABSTRACTThis study successfully synthesized a new zinc-based metal-organic framework material...

Public Health. 2026 Aug 28;259:106470. doi: 10.1016/j.puhe.2026.106470. Online ahead of print.ABSTRACTOBJECTIVES: Limited information is available on anabolic-androgenic steroids (AAS) use among young people. This study...

Cell Calcium. 2026 Aug 20;137:103184. doi: 10.1016/j.ceca.2026.103184. Online ahead of print.ABSTRACTBACKGROUND: The control of lymphatic permeability and flow is essential for homeostatic regulation of tissue...

Biomed Pharmacother. 2026 Aug 28;203:119867. doi: 10.1016/j.biopha.2026.119867. Online ahead of print.ABSTRACTβ2-containing nicotinic acetylcholine receptors (nAChRs) and dopamine D2 receptors (D2Rs) cooperate to shape striatal dopamine...

Am J Emerg Med. 2026 Aug 22;110:197-209. doi: 10.1016/j.ajem.2026.08.031. Online ahead of print.ABSTRACTOBJECTIVE: The objective of this study was to investigate the characteristics and trends...

Cancer Res Commun. 2026 Aug 28. doi: 10.1158/2767-9764.CRC-25-0829. Online ahead of print.ABSTRACTNon-small-cell lung cancer (NSCLC) is responsible for the majority of cancer-related mortality worldwide. Lung...

Drug Alcohol Rev. 2026 Sep;45(6):e70239. doi: 10.1111/dar.70239.ABSTRACTINTRODUCTION: Post-traumatic stress disorder (PTSD) commonly co-occurs with substance use disorders (SUD), yet few community-based SUD programs incorporate evidence-based...

Neuropharmacology. 2026 Aug 26:111154. doi: 10.1016/j.neuropharm.2026.111154. Online ahead of print.ABSTRACTMesolimbic endocannabinoid (eCB) signaling impacts reward-seeking behaviors that rely on incentive salience. We previously showed that...

J Affect Disord. 2026 Aug 26:122433. doi: 10.1016/j.jad.2026.122433. Online ahead of print.ABSTRACTBACKGROUND: Mindfulness-based cognitive therapy (MBCT) may improve sleep in major depressive disorder. This secondary...

Neurosci Biobehav Rev. 2026 Aug 26:106934. doi: 10.1016/j.neubiorev.2026.106934. Online ahead of print.ABSTRACTThe intersection of gaming and gambling has gained increasing attention due to their role...

Brain Behav Immun. 2026 Aug 26:106984. doi: 10.1016/j.bbi.2026.106984. Online ahead of print.NO ABSTRACTPMID:42648456 | DOI:10.1016/j.bbi.2026.106984

J Subst Use Addict Treat. 2026 Aug 26:210098. doi: 10.1016/j.josat.2026.210098. Online ahead of print.ABSTRACTINTRODUCTION: Clinicians providing methadone maintenance treatment (MMT) care must repeatedly decide, at...

Addict Behav. 2026 Aug 22;184:108841. doi: 10.1016/j.addbeh.2026.108841. Online ahead of print.ABSTRACTINTRODUCTION: Problematic gaming is recognized in both major diagnostic systems, as Internet Gaming Disorder (IGD)...

Addict Behav. 2026 Aug 23;184:108842. doi: 10.1016/j.addbeh.2026.108842. Online ahead of print.ABSTRACTSexualised drug use (SDU) is the intentional use of psychoactive substances to enhance sexual experiences....

J Addict Med. 2026 Aug 25. doi: 10.1097/ADM.0000000000001768. Online ahead of print.ABSTRACTOpioid use disorder and overdose are significant public health crises. Treatments for opioid overdose...

J Addict Med. 2026 Aug 25. doi: 10.1097/ADM.0000000000001767. Online ahead of print.ABSTRACTManaging substance withdrawal is often a necessary part of addiction care. However, without treatment...

J Addict Med. 2026 Aug 25. doi: 10.1097/ADM.0000000000001763. Online ahead of print.ABSTRACTThe release of the ASAM criteria 4th edition marks a paradigm shift by removing...

R I Med J (2013). 2026 Sep 1;109(9):53-55.ABSTRACTWe report a case of a 30-year-old woman with a history of intravenous drug use, who presented to...

R I Med J (2013). 2026 Sep 1;109(9):50-51.NO ABSTRACTPMID:42647838

Health Promot J Austr. 2026 Oct;37(4):e70240. doi: 10.1002/hpja.70240.ABSTRACTISSUE ADDRESSED: To explore Australian adolescents' perceptions of the risks and health harms associated with vaping and their...

Drug Alcohol Rev. 2026 Sep;45(6):e70245. doi: 10.1111/dar.70245.ABSTRACTInternational evidence increasingly supports integrating smoking cessation services within lung cancer screening programs, yet limited guidance exists for Aotearoa...

Tob Control. 2026 Aug 25:tc-2025-060007. doi: 10.1136/tc-2025-060007. Online ahead of print.ABSTRACTBACKGROUND: Electronic nicotine delivery systems (ENDS) can deliver nicotine at levels that rival or exceed...

Neurosci Biobehav Rev. 2026 Aug 25:106935. doi: 10.1016/j.neubiorev.2026.106935. Online ahead of print.ABSTRACTAs the field more actively recognizes the unique facets of adolescent neural, social, and...

J Endod. 2026 Aug 25:S0099-2399(26)00434-6. doi: 10.1016/j.joen.2026.08.013. Online ahead of print.ABSTRACTINTRODUCTION: Emergency dental pain remains a significant clinical challenge, with many patients experiencing moderate-to-severe pain...

J Subst Use Addict Treat. 2026 Aug 25:210097. doi: 10.1016/j.josat.2026.210097. Online ahead of print.ABSTRACTINTRODUCTION: Peer workers-nonclinical service providers with lived experience of recovery-are a growing...

J Subst Use Addict Treat. 2026 Aug 25:210102. doi: 10.1016/j.josat.2026.210102. Online ahead of print.ABSTRACTINTRODUCTION: Federal legislation requires states to notify child welfare agencies of all...

J Subst Use Addict Treat. 2026 Aug 25:210099. doi: 10.1016/j.josat.2026.210099. Online ahead of print.ABSTRACTBACKGROUND: A critical lack of knowledge exists about incarcerated individuals' preferences for...

J Subst Use Addict Treat. 2026 Aug 25:210095. doi: 10.1016/j.josat.2026.210095. Online ahead of print.ABSTRACTINTRODUCTION: Once-monthly (Sublocade®, BUP-SB) and weekly and monthly (Brixadi®, BUP-BX) long-acting injectable...

J Subst Use Addict Treat. 2026 Aug 25:210094. doi: 10.1016/j.josat.2026.210094. Online ahead of print.ABSTRACTLoneliness is highly pervasive among women with opioid use disorder (OUD). Emerging...

J Subst Use Addict Treat. 2026 Aug 25:210101. doi: 10.1016/j.josat.2026.210101. Online ahead of print.ABSTRACTBACKGROUND: The concept of powerlessness is central to the addiction and recovery...

Prog Neuropsychopharmacol Biol Psychiatry. 2026 Aug 25:111904. doi: 10.1016/j.pnpbp.2026.111904. Online ahead of print.ABSTRACTBACKGROUND: Methamphetamine use disorder (MUD) is associated with profound neurobiological alterations involving dopaminergic...

Pneumologie. 2026 Aug 25. doi: 10.1055/a-2847-7259. Online ahead of print.ABSTRACTThe tobacco industry has repeatedly adjusted its product strategy in the past. As soon as the...

Eur J Med Chem. 2026 Aug 21;319:119262. doi: 10.1016/j.ejmech.2026.119262. Online ahead of print.ABSTRACTPurine-derived scaffolds remain important in anticancer and antiviral drug discovery because their electronic...

Perspect Sex Reprod Health. 2026 Aug 21. doi: 10.1111/psrh.70079. Online ahead of print.ABSTRACTINTRODUCTION: Reproductive life planning can be a valuable component of reproductive health promotion....

Int J Ment Health Nurs. 2026 Aug;35(4):e70336. doi: 10.1111/inm.70336.ABSTRACTClinical supervision for health care workers is well established across many disciplines; however, supervision for nurses has...

Am J Clin Nutr. 2026 Aug 21:101489. doi: 10.1016/j.ajcnut.2026.101489. Online ahead of print.ABSTRACTAIM: To evaluate the measurement properties of a targeted nutrition-risk screening tool developed...

Int J Drug Policy. 2026 Aug 21;156:105471. doi: 10.1016/j.drugpo.2026.105471. Online ahead of print.ABSTRACTTrauma has a become a dominant causal explanation in psychological and public health...

Acta Psychol (Amst). 2026 Aug 21;270:107662. doi: 10.1016/j.actpsy.2026.107662. Online ahead of print.ABSTRACTInjuries among ultramarathoners are influenced by training load, recovery characteristics, anthropometric, and biomechanical characteristics....

Psychiatry Res. 2026 Aug 17;365:117404. doi: 10.1016/j.psychres.2026.117404. Online ahead of print.ABSTRACTBACKGROUND: Equality in clinical trial enrollment by sex is important for detecting sex-specific differences in...

Addict Behav. 2026 Aug 19;184:108839. doi: 10.1016/j.addbeh.2026.108839. Online ahead of print.ABSTRACTBACKGROUND: E-cigarette use and pain commonly co-occur in young adulthood, yet little is known about...

Prim Care Companion CNS Disord. 2026 Aug 20;28(4):26m04210. doi: 10.4088/PCC.26m04210.ABSTRACTBackground: Schizophrenia is a chronic and debilitating psychiatric disorder often accompanied by comorbid conditions, notably anxiety,...

Prim Care Diabetes. 2026 Aug 20:S1751-9918(26)00154-3. doi: 10.1016/j.pcd.2026.08.006. Online ahead of print.ABSTRACTAIMS: This study explores the experiences of diabetes distress among young adults, aged 18-29...

Lancet Digit Health. 2026 Aug 20:101057. doi: 10.1016/j.landig.2026.101057. Online ahead of print.NO ABSTRACTPMID:42624705 | DOI:10.1016/j.landig.2026.101057

J Affect Disord. 2026 Aug 19:122399. doi: 10.1016/j.jad.2026.122399. Online ahead of print.ABSTRACTBACKGROUND: Bipolar disorder (BD) is associated with differences in cerebral blood flow (CBF), a...

J Pediatr. 2026 Aug 19:115286. doi: 10.1016/j.jpeds.2026.115286. Online ahead of print.ABSTRACTOBJECTIVE: To evaluate longitudinal changes in diagnoses related to emergency department (ED) utilization and associated...

Addict Behav. 2026 Aug 12;184:108835. doi: 10.1016/j.addbeh.2026.108835. Online ahead of print.ABSTRACTBACKGROUND: The COVID-19 pandemic coincided with disruptions to mental health and substance use behaviors in...

Psychiatry Res. 2026 Aug 11;365:117380. doi: 10.1016/j.psychres.2026.117380. Online ahead of print.ABSTRACTBACKGROUND: Interest in cannabinoids for mental and substance use disorders is increasing. We examined experimental...

Work. 2026 Aug 17:10519815261476065. doi: 10.1177/10519815261476065. Online ahead of print.ABSTRACTBackgroundThe theoretical framework of the study draws on Self-Determination Theory (SDT), Job Demands-Resources (JD-R) theory, and...

Subst Use Misuse. 2026 Aug 11:1-8. doi: 10.1080/10826084.2026.2711947. Online ahead of print.ABSTRACTBackground: Social anxiety is associated with worse cannabis-related outcomes, but the mechanisms underlying this...

Drug Alcohol Rev. 2026 Sep;45(6):e70224. doi: 10.1111/dar.70224.ABSTRACTINTRODUCTION: The Australian Treatment Outcomes Profile (ATOP) is a brief clinical tool assessing substance use, health and well-being used...

Surg Endosc. 2026 Aug 10. doi: 10.1007/s00464-026-13270-x. Online ahead of print.ABSTRACTINTRODUCTION: There is an increased risk of hazardous alcohol use following metabolic and bariatric surgery...

Nat Protoc. 2026 Aug 10. doi: 10.1038/s41596-026-01406-1. Online ahead of print.ABSTRACTDrug self-administration has the greatest construct and predictive validity of the preclinical models for substance...

Addict Biol. 2026 Aug;31(8):e70182. doi: 10.1111/adb.70182.ABSTRACTCraving is one of the most robust proximal predictors of both treatment dropout and relapse during early recovery for alcohol...

Tob Control. 2026 Aug 10:tc-2026-060198. doi: 10.1136/tc-2026-060198. Online ahead of print.NO ABSTRACTPMID:42575700 | DOI:10.1136/tc-2026-060198

BMJ Health Care Inform. 2026 Aug 10;33(1):e102250. doi: 10.1136/bmjhci-2026-102250.NO ABSTRACTPMID:42575543 | DOI:10.1136/bmjhci-2026-102250

Behav Brain Res. 2026 Aug 10:116430. doi: 10.1016/j.bbr.2026.116430. Online ahead of print.ABSTRACTThe neuropeptide orexin/hypocretin regulates adaptive behaviors needed for survival, including food intake, sleep-wake regulation,...

Cancer Cell. 2026 Aug 10;44(8):1525-1532. doi: 10.1016/j.ccell.2026.07.004.ABSTRACTThe BCL-2 inhibitor venetoclax has transformed outcomes for older or frail patients with acute myeloid leukemia (AML), and its...

J Surg Res. 2026 Aug 10;326:619-629. doi: 10.1016/j.jss.2026.07.013. Online ahead of print.ABSTRACTINTRODUCTION: Perioperative opioid exposure remains a public health concern because short-term postoperative prescribing may...

Psychiatry Res. 2026 Jul 26;365:117340. doi: 10.1016/j.psychres.2026.117340. Online ahead of print.ABSTRACTBACKGROUND: A dose-response meta-analysis (DRMA) exploring serum/plasma clozapine and norclozapine concentrations in relation to efficacy...

Eur Arch Psychiatry Clin Neurosci. 2026 Aug 10. doi: 10.1007/s00406-026-02343-6. Online ahead of print.ABSTRACTBACKGROUND: With the widespread popularity of online gaming, gaming addiction has come...

Sci Rep. 2026 Aug 9;16(1):24552. doi: 10.1038/s41598-026-64265-6.ABSTRACTA sensitive and environmentally friendly spectrofluorimetric method was developed for the determination of guanfacine in pharmaceutical formulations. The method...

Addiction. 2026 Aug 9. doi: 10.1111/add.70578. Online ahead of print.NO ABSTRACTPMID:42571995 | DOI:10.1111/add.70578

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2026 Aug 7:1-12. doi: 10.3724/zdxbyxb-2025-0887. Online ahead of print.ABSTRACTMethamphetamine (METH) is highly addictive and can cause neurotoxicity...

Am J Dent. 2026 Aug;39(4):173-176.ABSTRACTPURPOSE: This cross-sectional study was to assess the prevalence of acute PAs in fibromyalgia patients.METHODS: Nine years of data from 2,108,676...

Addiction. 2026 Aug 9. doi: 10.1111/add.70569. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: United States (US) sales of oral nicotine pouches (ONPs) more than tripled from...

Drug Alcohol Rev. 2026 Sep;45(6):e70221. doi: 10.1111/dar.70221.ABSTRACTINTRODUCTION: Co-use of tobacco and cannabis is common among young adults and is associated with higher dependence and quitting...

Drug Alcohol Rev. 2026 Sep;45(6):e70228. doi: 10.1111/dar.70228.ABSTRACTINTRODUCTION: Older adults exhibit unique risks associated with poor mental health and substance use. The Beyond 50 study is...

Bone. 2026 Aug 9:118043. doi: 10.1016/j.bone.2026.118043. Online ahead of print.ABSTRACTAlcohol use disorder (AUD) is the most commonly diagnosed substance use disorder in the United States,...

J Affect Disord. 2026 Aug 9:122347. doi: 10.1016/j.jad.2026.122347. Online ahead of print.ABSTRACTINTRODUCTION: Electroconvulsive therapy (ECT) is the most effective intervention for depression, yet no validated...

Br J Anaesth. 2026 Aug 8:S0007-0912(26)00528-3. doi: 10.1016/j.bja.2026.06.040. Online ahead of print.NO ABSTRACTPMID:42570917 | DOI:10.1016/j.bja.2026.06.040

Eur J Pharmacol. 2026 Aug 8:179212. doi: 10.1016/j.ejphar.2026.179212. Online ahead of print.ABSTRACTAlprazolam (Alp) is a clinically common benzodiazepine (BZD) with a potential risk of abuse,...

Phytomedicine. 2026 Aug 3;160:158681. doi: 10.1016/j.phymed.2026.158681. Online ahead of print.ABSTRACTObesity exacerbates pathological injury in chronic kidney disease and ultimately leads to end-stage renal fibrosis. Extensive...

Drug Alcohol Depend. 2026 Jul 30;287:113290. doi: 10.1016/j.drugalcdep.2026.113290. Online ahead of print.ABSTRACTBACKGROUND: Peer recovery support services (PRS) delivered by individuals with lived experience of substance...

Addict Behav. 2026 Aug 7;183:108828. doi: 10.1016/j.addbeh.2026.108828. Online ahead of print.ABSTRACTBACKGROUND: Even with the most effective smoking cessation pharmacotherapies (i.e., varenicline or combination nicotine replacement...

Dev Cogn Neurosci. 2026 Jul 23;81:101784. doi: 10.1016/j.dcn.2026.101784. Online ahead of print.ABSTRACTABCD is an observational study of development and health from childhood through young adulthood....

Bioorg Chem. 2026 Aug 5;181:110335. doi: 10.1016/j.bioorg.2026.110335. Online ahead of print.ABSTRACTA library of N6-modified adenosine derivatives (compounds 7-36) was synthesized via a one-step reaction of...

J Drug Educ. 2026 Aug 8:472379261476179. doi: 10.1177/00472379261476179. Online ahead of print.ABSTRACTDescriptive norms are strongly related to college students' alcohol use; however, less is known...