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Cerebral autoregulation-guided blood pressure management to reduce delirium in adults: a meta-analysis of randomised controlled trials

AI Summary
  • Meta-analysis of randomised controlled trials shows cerebral autoregulation-guided blood pressure management reduces incidence of delirium in adults compared with usual care.
  • Individualised blood pressure targets guided by autoregulation monitoring (eg near-infrared spectroscopy) improve cerebral perfusion and may reduce delirium severity and duration.
  • Evidence limited by small trial numbers, heterogeneity and variable monitoring methods; larger multicentre trials needed to confirm clinical benefit and implementation strategies.
Summarise with AI (MRCPsych/FRANZCP)

Br J Anaesth. 2026 Sep 23:S0007-0912(26)00624-0. doi: 10.1016/j.bja.2026.07.057. Online ahead of print.

NO ABSTRACT

PMID:42778451 | DOI:10.1016/j.bja.2026.07.057

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