Psychological Adjustment and Mental Health Among Those Seeking Pain Rehabilitation Treatment

14/11/2026

AI Summary

Chronic pain strongly linked to psychological distress, functional impairment, and diminished quality of life in rehabilitation seekers and people with disability.
Introduces the neural exposome: a lifespan, integrative model framing pain as cumulative internal, external, and behavioural exposures shaping nervous system function.
Clinical implication: assessment and treatment should address cumulative exposures and mental health to improve rehabilitation outcomes.

TL;DR (AI Generated)

Phys Med Rehabil Clin N Am. 2027 Feb;38(1):155-177. doi: 10.1016/j.pmr.2026.08.009.

This article introduces the neural exposome as an integrative, lifespan-oriented model for understanding pain as the product of cumulative result of internal, external, and behavioral exposures that shape nervous system function over time.

Basic summary

Phys Med Rehabil Clin N Am. 2027 Feb;38(1):155-177. doi: 10.1016/j.pmr.2026.08.009. Epub 2026 Sep 15.

ABSTRACT

Chronic pain is a leading cause of disability worldwide and is strongly intertwined with psychological distress, functional impairment, and reduced quality of life, particularly among individuals seeking pain rehabilitation services and those living with disability. This article introduces the neural exposome as an integrative, lifespan-oriented model for understanding pain as the product of cumulative endogenous, exogenous, behavioral exposures that shape nervous system function over time. This article introduces the neural exposome as an integrative, lifespan-oriented model for understanding pain as the product of cumulative result of internal, external, and behavioral exposures that shape nervous system function over time.

PMID:43025915 | DOI:10.1016/j.pmr.2026.08.009

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