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Reply to: “Pulmonary Embolism During Clozapine and Olanzapine Treatment: An Underrecognized Clinical Risk Highlighted by Pharmacovigilance Data”

AI Summary
  • Pharmacovigilance data indicate an association between clozapine or olanzapine exposure and pulmonary embolism, warranting clinical awareness.
  • Signal interpretation limited by underreporting, confounding medical risk factors, and inability to establish causality from spontaneous reports.
  • Clinicians should assess venous thromboembolism risk, counsel patients, monitor for symptoms, and support prospective studies to clarify causality.
Summarise with AI (MRCPsych/FRANZCP)

J Clin Psychopharmacol. 2026 Oct 19. doi: 10.1097/JCP.0000000000002285. Online ahead of print.

NO ABSTRACT

PMID:42895188 | DOI:10.1097/JCP.0000000000002285

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