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Suicidal Ideation and Attempts Among Youth With Sickle Cell Disease Seeking Acute Care

AI Summary
  • 3.08% of youth with sickle cell disease (10 to 18 years) had ≥1 suicidal ideation or attempt; 0.76% of acute encounters included SI/SA.
  • Female sex (p < 0.0001) and public insurance (p = 0.0009) were significantly associated with suicidal ideation or attempts.
  • Findings highlight the need for suicide screening in acute care settings for youth with sickle cell disease.
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Pediatr Blood Cancer. 2026 Jul 27:e70565. doi: 10.1002/1545-5017.70565. Online ahead of print.

ABSTRACT

Suicidal ideation (SI) and suicidal attempt (SA) rates are rising among youth in the United States; however, research on SI/SA in youth with sickle cell disease (Y-SCD) remains limited. Using the Pediatric Health Information System, we examined the prevalence and demographic factors associated with SI/SA among Y-SCD (10-18 years) seeking acute care between 2015 and 2024. Overall, 358 (3.08%) Y-SCD had ≥ 1 SI/SA encounter and 0.76% of all acute encounters among Y-SCD included a code for SI/SA. Female sex (p < 0.0001) and public insurance (p = 0.0009) were significantly associated with SI/SA. Findings highlight the need for suicide screening in acute care settings for Y-SCD.

PMID:42504874 | DOI:10.1002/1545-5017.70565

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