Tag: Psychosis

Harm Reduct J. 2026 Sep 7;23(1):146. doi: 10.1186/s12954-026-01517-8.ABSTRACTBACKGROUND: The contemporary landscape of psychoactive substance regulation is characterized by a striking policy paradox. On one hand...

Transl Psychiatry. 2026 Sep 2;16(1):455. doi: 10.1038/s41398-026-04362-2.ABSTRACTAlterations in telomere length (TL), a marker of cellular ageing, have been reported in individuals with severe mental disorders...

Emerg Med Australas. 2026 Oct;38(5):e70336. doi: 10.1111/1742-6723.70336.ABSTRACTOBJECTIVE: Acid-base patterns and their association with clinical outcomes have not been characterised using venous-specific reference ranges in a...

J Child Adolesc Trauma. 2026 Feb 7;19(3):1061-1071. doi: 10.1007/s40653-026-00829-y. eCollection 2026 Sep.ABSTRACTChildhood abuse is still a prevalent problem in modern societies. Adolescents with a history...

J Child Psychol Psychiatry. 2026 Sep 6. doi: 10.1111/jcpp.70224. Online ahead of print.ABSTRACTBACKGROUND: Widespread neurocognitive impairments exist in children at familial high-risk of schizophrenia (FHR-SZ),...

Hum Brain Mapp. 2026 Sep;47(13):e70628. doi: 10.1002/hbm.70628.ABSTRACTElectroencephalography (EEG) provides real-time, dynamic insights into brain function, making it a valuable tool for the screening, diagnosis, and...

Psychiatry Res. 2026 Aug 20;366:117410. doi: 10.1016/j.psychres.2026.117410. Online ahead of print.ABSTRACTOBJECTIVES: Phenotypic heterogeneity between suicidal ideation (SI) only and suicide attempt (SA) in major depressive...

J Behav Ther Exp Psychiatry. 2026 Sep 2;94:102134. doi: 10.1016/j.jbtep.2026.102134. Online ahead of print.ABSTRACTIndividuals with schizophrenia exhibit a range of verbal and nonverbal impairments during...

Sci Rep. 2026 Sep 5;16(1):27818. doi: 10.1038/s41598-026-70148-7.ABSTRACTGlobally, cannabis ranks third in psychoactive substance prevalence after nicotine and alcohol, with heavy use linked to psychosis, anxiety,...

Am J Case Rep. 2026 Sep 5;27:e953812. doi: 10.12659/AJCR.953812.ABSTRACTBACKGROUND Cerebral venous thrombosis (CVT) is an uncommon form of stroke with highly variable clinical manifestations. Although...

BMC Psychiatry. 2026 Sep 3;26(1):698. doi: 10.1186/s12888-026-08587-9.ABSTRACTBACKGROUND: Systemic inflammatory and nutritional indices derived from hematological parameters have emerged as accessible markers of immune imbalance. Although...

Int Clin Psychopharmacol. 2026 Sep 2. doi: 10.1097/YIC.0000000000000634. Online ahead of print.ABSTRACTLong-acting injectable (LAI) antipsychotics are important for improving adherence and preventing relapse. Risperidone in-situ...

Nat Rev Neurol. 2026 Sep 1. doi: 10.1038/s41582-026-01260-5. Online ahead of print.ABSTRACTSymptomatic treatment remains central to the clinical management of Alzheimer disease (AD), even as...

Schizophr Res. 2026 Sep 1;297:314-329. doi: 10.1016/j.schres.2026.08.018. Online ahead of print.ABSTRACTAIM: Cognitive Behavioural Therapy for psychosis (CBTp) is a recommended psychosocial treatment for psychosis, yet...

Trials. 2026 Aug 28;27(1):552. doi: 10.1186/s13063-026-09879-x.ABSTRACTBACKGROUND: Negative symptoms are experienced by up to 60% of the individuals with schizophrenia and represent a stronger indicator of...

BMJ Open. 2026 Aug 28;16(8):e114585. doi: 10.1136/bmjopen-2025-114585.ABSTRACTINTRODUCTION: The course of psychotic disorders typically involves relapses. Early warning signs vary between individuals and are difficult to...

BMJ. 2026 Aug 28;394:e635470. doi: 10.1136/bmj-2026-635470.ABSTRACTSchizophrenia is a common and severe mental condition with onset usually in late adolescence and young adulthood. Schizophrenia is caused...

J Affect Disord. 2026 Aug 28:122429. doi: 10.1016/j.jad.2026.122429. Online ahead of print.ABSTRACTBACKGROUND: Despite availability of antidepressant treatments (ADTs), many patients with depression do not achieve...

Schizophr Res. 2026 Aug 28;297:270-276. doi: 10.1016/j.schres.2026.08.012. Online ahead of print.ABSTRACTAdverse childhood experiences (ACEs) are associated with elevated risk for psychosis-spectrum outcomes, yet less is...

Schizophr Res. 2026 Aug 28;297:263-269. doi: 10.1016/j.schres.2026.08.014. Online ahead of print.ABSTRACTSocial cognitive difficulties among those with schizophrenia and first episode psychosis (FEP) are well-documented, but...

Schizophr Res. 2026 Aug 28;297:254-262. doi: 10.1016/j.schres.2026.08.022. Online ahead of print.ABSTRACTBACKGROUND: Antipsychotic-induced weight gain (AIWG) is a major clinical concern in schizophrenia spectrum disorders. While...

Medicina (Kaunas). 2026 Aug 14;62(8):1564. doi: 10.3390/medicina62081564.ABSTRACTBackground and Objectives: The COVID-19 pandemic and the accompanying containment measures substantially altered everyday life and created conditions that...

Nutrients. 2026 Aug 20;18(16):2726. doi: 10.3390/nu18162726.ABSTRACTBackground/Objectives: Dietary supplements (DSs) and over-the-counter (OTC) medications for mood improvement and stress relief are widely used, but little is...

Nutrients. 2026 Aug 10;18(16):2606. doi: 10.3390/nu18162606.ABSTRACTBackground/Objectives: Long-term recovery following adolescent anorexia nervosa (AN) remains incompletely understood because restoration of nutritional status does not necessarily coincide...

Life (Basel). 2026 Aug 16;16(8):1344. doi: 10.3390/life16081344.ABSTRACTBackground: Translocator Protein (TSPO) is a transmembrane protein located in the mitochondrial outer membrane and highly expressed in the...

Life (Basel). 2026 Aug 12;16(8):1321. doi: 10.3390/life16081321.ABSTRACTIntroduction: Transnasal penetrating intracranial injuries represent an exceptionally rare form of traumatic brain injury, characterized by high mortality and...

J Clin Med. 2026 Aug 18;15(16):6393. doi: 10.3390/jcm15166393.ABSTRACTNonadherence to medications for psychosis is a major challenge in the management of schizophrenia and is associated with...

Int J Environ Res Public Health. 2026 Jul 24;23(8):952. doi: 10.3390/ijerph23080952.ABSTRACTFamily-centred approaches are being increasingly recognized as integral to inclusive mental health care. Although substantial...

Healthcare (Basel). 2026 Aug 14;14(16):2541. doi: 10.3390/healthcare14162541.ABSTRACTBackground: Job stress is a pervasive issue in modern workplaces and is associated with numerous adverse outcomes, including employees'...

Brain Sci. 2026 Aug 16;16(8):867. doi: 10.3390/brainsci16080867.ABSTRACTA pro-inflammatory state, characterized by elevated levels of pro-inflammatory cytokines, is frequently reported among individuals presenting with primary first-episode...

Brain Sci. 2026 Jul 26;16(8):787. doi: 10.3390/brainsci16080787.ABSTRACTBackground/Objectives: Cannabis use is prevalent in first-episode psychosis (FEP) and is associated with poor clinical outcomes. Cariprazine, a dopamine...

Psychiatr Serv. 2026 Aug 27:appips20260106. doi: 10.1176/appi.ps.20260106. Online ahead of print.ABSTRACTOBJECTIVE: Retention in coordinated specialty care (CSC) is critical for optimizing outcomes of first-episode psychosis,...

Eur Arch Psychiatry Clin Neurosci. 2026 Aug 27. doi: 10.1007/s00406-026-02357-0. Online ahead of print.ABSTRACTBACKGROUND: Suicidal ideation (SI) is highly prevalent in patients with depression and...

NPJ Parkinsons Dis. 2026 Jul 28;12(1):203. doi: 10.1038/s41531-026-01474-w.ABSTRACTNon-motor symptoms (NMS) in Parkinson's disease (PD) are clinically impactful and lack reliable blood-based biomarkers. Neural-derived extracellular vesicles...

J Affect Disord. 2026 Aug 26:122430. doi: 10.1016/j.jad.2026.122430. Online ahead of print.NO ABSTRACTPMID:42648554 | DOI:10.1016/j.jad.2026.122430

Schizophr Res. 2026 Aug 26;297:231-240. doi: 10.1016/j.schres.2026.08.009. Online ahead of print.ABSTRACTINTRODUCTION: Social and occupational impairment is common in early psychosis, yet predictors of functional outcome...

J Korean Med Sci. 2026 Aug 24;41(33):e212. doi: 10.3346/jkms.2026.41.e212.ABSTRACTBACKGROUND: Public concern regarding homicides committed by individuals with schizophrenia has intensified in recent years. Although the...

Am J Psychiatry. 2026 Aug 26:appiajp20250473. doi: 10.1176/appi.ajp.20250473. Online ahead of print.ABSTRACTOBJECTIVE: An increasingly compelling body of literature indicates that the glucocorticoid receptor cochaperone FK506-binding...

Brain Behav Immun. 2026 Aug 25:106967. doi: 10.1016/j.bbi.2026.106967. Online ahead of print.ABSTRACTAIMS: Psychotic experiences (PEs) are relatively common in youth and are associated with increased...

Acta Psychol (Amst). 2026 Aug 25;270:107703. doi: 10.1016/j.actpsy.2026.107703. Online ahead of print.ABSTRACTSchizophrenia, characterized by prominent positive and negative symptoms, is associated with disturbances in agency....

Soc Sci Med. 2026 Aug 17;407:119715. doi: 10.1016/j.socscimed.2026.119715. Online ahead of print.ABSTRACTSchizophrenia is unequally distributed across social hierarchies and is associated with stratified pathways of...

Cortex. 2026 Aug 6;204:154-169. doi: 10.1016/j.cortex.2026.07.007. Online ahead of print.ABSTRACTSchizophrenia and related psychoses are characterized by reductions in hippocampal volume and morphometric hippocampal-cortical covariance. No...

Schizophr Res. 2026 Aug 22;297:191-193. doi: 10.1016/j.schres.2026.08.017. Online ahead of print.NO ABSTRACTPMID:42632275 | DOI:10.1016/j.schres.2026.08.017

NPJ Digit Med. 2026 Aug 20;9(1):644. doi: 10.1038/s41746-026-03054-x.ABSTRACTChatbots based on large language models (LLMs) are increasingly used in everyday life. Although concerns about negative impacts...

Clin Psychol Psychother. 2026 Jul-Aug;33(4):e70303. doi: 10.1002/cpp.70303.ABSTRACTINTRODUCTION: This systematic review and meta-analysis aims to examine the relationship between childhood maltreatment and the course and prognosis...

Mol Psychiatry. 2026 Aug 20. doi: 10.1038/s41380-026-03832-9. Online ahead of print.ABSTRACTWhite matter (WM) alterations are well documented in individuals at clinical high-risk for psychosis (CHR-P)...

JAMA Psychiatry. 2026 Aug 19. doi: 10.1001/jamapsychiatry.2026.2510. Online ahead of print.ABSTRACTIMPORTANCE: Mania or hypomania, the pathognomonic feature of bipolar disorder (BD), is associated with reward...

Soc Psychiatry Psychiatr Epidemiol. 2026 Aug 19. doi: 10.1007/s00127-026-03202-4. Online ahead of print.ABSTRACTBACKGROUND: Many caregivers of people with psychosis are at risk of distress, which...

Addiction. 2026 Aug 19. doi: 10.1111/add.70576. Online ahead of print.ABSTRACTBACKGROUND AND AIMS: Use of derived intoxicating cannabinoid products (DICPs) has grown in the United States...

Asia Pac Psychiatry. 2026 Sep;18(3):e70033. doi: 10.1111/appy.70033.ABSTRACTPeople with psychotic disorders have higher dementia risk. This study aimed to investigate the prevalence and incidence of dementia...

Schizophr Bull Open. 2026 Jul 24;7(1):sgag030. doi: 10.1093/schizbullopen/sgag030. eCollection 2026.ABSTRACTBACKGROUND: Previous findings showed decreased frontal left gray matter (FLGM) volume predicted working memory impairments over...

Public Health Chall. 2026 Aug 18;5(3):e70352. doi: 10.1002/puh2.70352. eCollection 2026 Sep.ABSTRACTBACKGROUND: This cross-sectional study examines whether intolerance of uncertainty (IU) is indirectly associated with the...

Schizophr Bull Open. 2026 Jul 21;7(1):sgag028. doi: 10.1093/schizbullopen/sgag028. eCollection 2026.ABSTRACTBACKGROUND AND HYPOTHESIS: Cognitive models conceptualize paranoia in schizophrenia spectrum disorders as driven and maintained by...

Case Rep Psychiatry. 2026 Aug 18;2026:4635562. doi: 10.1155/crps/4635562. eCollection 2026.ABSTRACTINTRODUCTION: Paliperidone palmitate 3-monthly (PP3M) is a long-acting Injection (LAI) formulation of the anti-psychotic medication paliperidone,...

Front Mol Neurosci. 2026 Aug 4;19:1903770. doi: 10.3389/fnmol.2026.1903770. eCollection 2026.ABSTRACTThe gut microbiota exhibits diurnal oscillations that are increasingly recognized as important modulators of host physiology,...

Australas Psychiatry. 2026 Aug 18:10398562261479310. doi: 10.1177/10398562261479310. Online ahead of print.ABSTRACTIt is increasingly understood that rare genetic variation confers significant risk for various psychiatric phenotypes,...

Psychiatry Investig. 2026 Aug;23(8):1071-1079. doi: 10.30773/pi.2026.0038. Epub 2026 Aug 4.ABSTRACTOBJECTIVE: Psychotic symptoms are common in Parkinson's disease (PD), yet it remains unclear whether these manifestations...

Lancet HIV. 2026 Aug 18:S2352-3018(26)00147-5. doi: 10.1016/S2352-3018(26)00147-5. Online ahead of print.ABSTRACTBACKGROUND: Despite a general improvement in the HIV burden over the past two decades, gendered...

Diabetes Care. 2026 Aug 18:dc260861. doi: 10.2337/dc26-0861. Online ahead of print.ABSTRACTOBJECTIVE: The epidemiology of diabetes and its complications is changing due to increasingly younger ages...

Biol Psychiatry. 2026 Aug 18:S0006-3223(26)01385-5. doi: 10.1016/j.biopsych.2026.06.025. Online ahead of print.ABSTRACTBACKGROUND: Increases in cannabis use, potency, and legal liberalization have raised concerns about psychiatric consequences....

Harv Rev Psychiatry. 2026 Jul 17. doi: 10.1097/HRP.0000000000000474. Online ahead of print.ABSTRACTInsight in psychiatry has historically been defined through symptom awareness, illness attribution, and recognition...

Br J Clin Psychol. 2026 Aug 14. doi: 10.1111/bjc.70092. Online ahead of print.ABSTRACTOBJECTIVES: People who hear voices commonly experience high levels of shame. This study...

J Smok Cessat. 2020 Sep;15(3):157-162. doi: 10.1017/jsc.2020.19. Epub 2020 Jul 9.ABSTRACTINTRODUCTION: Individuals with schizophrenia are more likely to smoke and less likely to quit smoking...

J Taibah Univ Med Sci. 2026 Aug 3;21(4):856-862. doi: 10.1016/j.jtumed.2026.07.010. eCollection 2026 Aug.ABSTRACTRoutine urine toxicology screening may be misleading when adolescents present with acute psychotic...

Pregnancy (Hoboken). 2026 May 19;2(3):e70305. doi: 10.1002/pmf2.70305. eCollection 2026 May.ABSTRACTOBJECTIVE: Previous research has shown that preventive counseling for women at high risk of perinatal depression...

Expert Rev Neurother. 2026 Aug 14:1-20. doi: 10.1080/14737175.2026.2718395. Online ahead of print.ABSTRACTINTRODUCTION: Psychosis is increasingly understood as a disorder of brain systems that are also...

J Geriatr Psychiatry Neurol. 2026 Aug 11:8919887261470005. doi: 10.1177/08919887261470005. Online ahead of print.ABSTRACTBackgroundAlzheimer's Disease (AD) is characterised by progressive cognitive decline. Cholinesterase inhibitors (ChEI) (donepezil,...

Curr Neuropharmacol. 2026 Jul 30. doi: 10.2174/011570159X480041260722224459. Online ahead of print.ABSTRACTOBJECTIVE: Major Depressive Disorder (MDD) with atypical features, briefly named Atypical Depression (AFD), exhibits affective...

Neuropsychopharmacology. 2026 Aug 10. doi: 10.1038/s41386-026-02522-y. Online ahead of print.ABSTRACTDespite growing evidence from magnetic resonance spectroscopy studies of glutamatergic and GABAergic abnormalities in schizophrenia, in...

Psychogeriatrics. 2026 Sep;26(5):e70205. doi: 10.1111/psyg.70205.ABSTRACTBACKGROUND: Very late-onset schizophrenia-like psychosis (VLOSLP) is clinically heterogeneous, and its relationship with dementia-related neurodegenerative disease remains unresolved. We examined whether...

J Affect Disord. 2026 Aug 10:122363. doi: 10.1016/j.jad.2026.122363. Online ahead of print.ABSTRACTBACKGROUND: The present study aimed to address the gap between treatment guidelines and real-world...

Cureus. 2026 Jul 9;18(7):e112367. doi: 10.7759/cureus.112367. eCollection 2026 Jul.ABSTRACTThe intersection of pediatric psychiatry and infectious disease can present complex diagnostic challenges, particularly when symptoms of...

Neurosci Biobehav Rev. 2026 Aug 9:106897. doi: 10.1016/j.neubiorev.2026.106897. Online ahead of print.ABSTRACTPsychosis is increasingly conceptualized as a disorder of distributed neural circuits rather than focal...

Aust N Z J Psychiatry. 2026 Aug 7:48674261471316. doi: 10.1177/00048674261471316. Online ahead of print.ABSTRACTBACKGROUND: Young people with first-episode psychosis experience high rates of disruption in...

J Oral Facial Pain Headache. 2026 Jul;40(4):76-83. doi: 10.22514/jofph.2026.050. Epub 2026 Jul 12.ABSTRACTBACKGROUND: Making a measure of orofacial pain available for use among Arabic-speakers might...

Mol Psychiatry. 2026 Aug 3. doi: 10.1038/s41380-026-03749-3. Online ahead of print.ABSTRACTLate-onset psychosis (LOP) exhibits distinct clinical features compared with younger-onset psychosis. Although postmortem and epidemiological...

NPJ Digit Med. 2026 Aug 3;9(1):594. doi: 10.1038/s41746-026-03053-y.ABSTRACTLanguage is central to psychosis, making it a key focus for both clinical evaluation and research. Many automated...

Schizophr Bull. 2026 Jul 3;52(4):sbag086. doi: 10.1093/schbul/sbag086.ABSTRACTBACKGROUND: People taking antipsychotic medicines and those with severe mental illness experience elevated cardiovascular risk compared to the general...

Schizophr Bull. 2026 Jul 3;52(4):sbag056. doi: 10.1093/schbul/sbag056.ABSTRACTBACKGROUND AND HYPOTHESIS: Processing speed and verbal learning are linked to functioning in people at clinical high-risk for psychosis...

Cureus. 2026 Jul 3;18(7):e111997. doi: 10.7759/cureus.111997. eCollection 2026 Jul.ABSTRACTParasocial attachments are one-sided emotional relationships with public figures that are generally benign and may provide emotional...

Cureus. 2026 Jun 29;18(6):e111781. doi: 10.7759/cureus.111781. eCollection 2026 Jun.ABSTRACTNeuropsychiatric symptoms of Marfan syndrome (MFS) are rarely described, yet accumulating evidence suggests a possible association with...