- The first 1000 days postconception are a critical sensitive period with high vulnerability to environmental factors affecting short and long term neurobehavioural outcomes.
- Ninety percent of brain development occurs in the first three years through gene and environment interactions shaping neurodevelopment.
- Environmental counselling is underprioritised despite lower cost and greater population impact; public policies should protect early childhood, especially vulnerable groups.
Medicina (B Aires). 2026 Aug;86 Suppl 3:110-116.
ABSTRACT
The first 1000 days postconception are the critical and sensitive period for neurodevelopment, with the greatest exposure and vulnerability to environmental factors with short- and long-term neurobehavioral impact. Ninety percent of the brain is built in the first three years of life through the interaction of genetic and environmental factors. Genetic counseling is erroneously prioritized over environmental counseling, which is less costly and has a greater impact on the population. This paper analyzes the role of some environmental risk and protective factors that influence neurodevelopment and mental health, as inputs for promoting public policies to protect early childhood, especially in vulnerable populations.
PMID:42659560
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