AI Summary
- Single-infusion ketamine shows a promising antidepressant signal in older adults with depression and mild cognitive impairment.
- Observed increased falls raise safety concerns, necessitating fall risk assessment and close monitoring in this vulnerable population.
- Cognitive safety remains uncertain and demands rigorous evaluation and longer-term studies before widespread clinical adoption.
Am J Geriatr Psychiatry. 2026 Jul 30:S1064-7481(26)00479-3. doi: 10.1016/j.jagp.2026.07.012. Online ahead of print.
NO ABSTRACT
PMID:42632764 | DOI:10.1016/j.jagp.2026.07.012
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